Induction of leukemia-specific CD8+ cytotoxic t cells with autologous myeloid leukemic cells maturated with a fiber-modified adenovirus encoding TNF-α

Molecular Therapy

Volumn 11, Issue 6, 2005, Pages 950-959

  Saudemont, Aurore ^a,b   Corm, Selim ^a,b,c   Wickham, Thomas ^d   Hetuin, Dominique ^a,b   Quesnel, Bruno ^a,b,c  

^a Institut de Recherche sur le Cancer de Lille   (France)

^b Institut Fédéatif de Recherche 114   (France)

^c LILLE UNIVERSITY HOSPITAL   (France)

^d GENVEC INC   (United States)

Author keywords

Acute; Adenovirus; Antigen presenting cells; Cytotoxic T lymphocytes; Dendritic cells; Fiber protein; Myeloid leukemia; Tumor necrosis factor

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOVIRUS VECTOR; B7 ANTIGEN; CD8 ANTIGEN; CD86 ANTIGEN; CYTOKINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; RAPAMYCIN; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; T6 ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; WORTMANNIN;

ACUTE GRANULOCYTIC LEUKEMIA; ADENOVIRUS; ADOPTIVE IMMUNOTHERAPY; ANTIGEN PRESENTING CELL; ARTICLE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL GROWTH; CELL MATURATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; INHIBITION KINETICS; LEUKEMIA CELL; MONOCYTE; PROTEIN EXPRESSION; REPRODUCIBILITY; SIGNAL TRANSDUCTION; VIRAL GENE DELIVERY SYSTEM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACUTE DISEASE; ADENOVIRIDAE; ANTIGEN-PRESENTING CELLS; CAPSID PROTEINS; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; CYTOTOXICITY, IMMUNOLOGIC; HUMANS; LEUKEMIA, MYELOID; PHENOTYPE; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC; TRANSDUCTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

ADENOVIRIDAE;

EID: 19444383562     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2004.12.016     Document Type: Article

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