Nef induces apoptosis by activating JNK signaling pathway and inhibits NF-κB-dependent immune responses in Drosophila

Journal of Cell Science

Volumn 118, Issue 9, 2005, Pages 1851-1859

  Lee, Sung Bae ^a   Park, Jeehye ^a   Jung, Jae U ^b   Chung, Jongkyeong ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Drosophila; JNK; Nef; NF B

Indexed keywords

CASPASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; NEF PROTEIN; PEPTIDE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MEMBRANE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVATION; FORELIMB; GENETIC ANALYSIS; GENETIC CONSERVATION; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MAMMAL; MODULATION; MYRISTYLATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TARGET CELL; TRANSGENIC ANIMAL; WILD TYPE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; BLOTTING, NORTHERN; BROMODEOXYURIDINE; CASPASES; CELL MEMBRANE; CELL PROLIFERATION; CLONING, MOLECULAR; DROSOPHILA; GENE PRODUCTS, NEF; HIV-1; IMMUNE SYSTEM; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LAC OPERON; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MODELS, BIOLOGICAL; MYRISTIC ACIDS; NF-KAPPA B; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSGENES;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; JANUS; MAMMALIA;

EID: 19444381774     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02312     Document Type: Article

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