Evolution of Function in the Crotonase Superfamily: (3S)-Methylglutaconyl-CoA Hydratase from Pseudomonas putida

Biochemistry

Volumn 43, Issue 16, 2004, Pages 4646-4654

  Wong, Brian J ^a   Gerlt, John A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLATION; CATALYSIS; COENZYMES; ENZYME INHIBITION; ESTERS; GENES; GLUCOSE; HOLE MOBILITY; HYDRATION; NEGATIVE IONS; SCAFFOLDS;

ACYL ESTERS; CROTONASE; MITOCHONDRIAL; OXYANION HOLE; STRUCTURAL SCAFFOLD;

BIOCHEMISTRY;

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; CARBOXYLIC ACID DERIVATIVE; ENOYL COENZYME A HYDRATASE; GLUTAMIC ACID; GLUTAMINE; HYDROLYASE; LEUCINE; METHYLGLUTACONYL COENZYME A HYDRATASE; UNCLASSIFIED DRUG;

ARTICLE; CATABOLISM; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; MAMMAL; NONHUMAN; OPERON; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS PUTIDA;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BACTERIAL PROTEINS; BINDING SITES; CATALYSIS; EVOLUTION, MOLECULAR; GENOME, BACTERIAL; GLUTAMIC ACID; HYDRO-LYASES; KINETICS; MOLECULAR SEQUENCE DATA; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS PUTIDA; RATS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); EUKARYOTA; MAMMALIA; NEGIBACTERIA; PROKARYOTA; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS PUTIDA;

EID: 1942534655     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0360307     Document Type: Article

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