Morphine Prevents Glutamate-Induced Death of Primary Rat Neonatal Astrocytes Through Modulation of Intracellular Redox

Immunopharmacology and Immunotoxicology

Volumn 26, Issue 1, 2004, Pages 17-28

  Lee, Jienny ^a   Kim, Myung Sunny ^a,c   Park, Channy ^a   Jung, Eun Bae ^a   Choi, Duk Hwa ^a   Kim, Tae Yo ^a   Moon, Sung Keun ^b   Park, Raekil ^a  

^a Wonkwang University   (South Korea)

^b Wonkwang University   (South Korea)

^c Korea Food Research Institute   (South Korea)

Author keywords

Glutamate; Mitochondrial permeability transition; Morphine; Oxidative damage

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; GLUTAMIC ACID; GLUTATHIONE; MORPHINE; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; NALOXONE; OPIATE RECEPTOR; RECEPTOR SUBTYPE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL CULTURE; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL VIABILITY; CONTROLLED STUDY; CYTOLYSIS; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; GLIA CELL; MITOCHONDRION; NEUROPROTECTION; NEWBORN; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ACETYLCYSTEINE; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; ASTROCYTES; BENZENEACETAMIDES; BENZIMIDAZOLES; BISBENZIMIDE; CARBOCYANINES; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; DIZOCILPINE MALEATE; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALIN, D-PENICILLAMINE (2,5)-; GLUTAMIC ACID; GLUTATHIONE; HYDROGEN PEROXIDE; ION CHANNELS; MICROSCOPY, FLUORESCENCE; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MORPHINE; NALOXONE; NEUROGLIA; OXIDATION-REDUCTION; OXIDATIVE STRESS; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, OPIOID; RHODAMINE 123;

ANIMALIA;

EID: 1942519883     PISSN: 08923973     EISSN: None     Source Type: Journal    
DOI: 10.1081/IPH-120029941     Document Type: Article

References (33)

1. Fonnum, F. Glutamate: a neurotransmitter in mammalian brain. J. Neurochem. 1984, 42, 1-11.
2. Choi, D.W. Glutamate neurotoxicity and disease of nervous system. Neuron 1988, 1, 623-634.
3. Nichols, D.G.; Attwell, D. The release and uptake of excitatory amino acids. Trends Pharmacol. Sci. 1990, 11, 462-468.
4. Bondy, S.C.; LeBel, C.P. The relationship between excitotoxicity and oxidative stress in the central nervous system. Free Radic. Biol. Med. 1993, 14, 633-642.
5. Coyle, J.T.; Puttfarcken, P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 1993, 262, 689-695.
6. Murphy, T.H.; Miyamoto, M.; Sastre, A.; Schnaar, R.L.; Coyle, J.T. Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 1989, 2, 1547-1558.
7. Bannai, S. Exchange of cystine and gluramate across a plasma membrane of human fibroblasts. J. Biol. Chem. 1986, 261, 2256-2263.
8. Cho, Y.; Bannai, S. Uptake of glutamate and cystein in C6 glioma cells and in cultured astrocytes. J. Neurochem. 1990, 55, 2091-2097.
9. Kato, S.; Negishi, K.; Mawatari, K.; Kuo, C.H. A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion. Neuroscience 1992, 48, 903-914.
10. Froissard, P.; Duval, D. Cytotoxic effects of glutamic acid on PC12 cells. Neurochem. Int. 1994, 24, 485-493.
11. Oka, A.; Belliveau, M.J.; Rosenberg, P.A.; Volpe, J.J. Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention. J. Neurosci. 1993, 13, 1441-1453.
12. McCay, P.B.; Powell, S.R. Relationship between glutathione and chemically induced lipid peroxidation. In Glutathione Chemical, Biochemical and Medical Aspects. Part B; Dolphin, D., Poulson, D., Arvamovic, O., Eds.; Wiley-Liss, Inc.: New York; 1989; 111-151.
13. Meister, A.; Anderson, M.E. Glutathione. Annu. Rev. Biochem. 1983, 49, 5870-5878.
14. Nestler, E.J. Under siege. The brain on opiate. Neuron 1996, 16, 897-900.
15. Nestler, E.J.; Aghajanian, G.K. Molecular and cellular basis of addiction. Science 1997, 278, 58-63.
16. Koob, G.F.; Sanna, P.P.; Bloom, F.E. Neuroscience of addiction. Neuron 1998, 21, 467-476.
17. Koichi, T.; Eric, H.; Yuji, Y.; Sten, G.E. Effects of neuroactive substances on the morphine-induced respiratory depression; an in vitro study. Brain Res. 2000, 884, 201-205.
18. MacKay, K.B.; Patel, T.R.; Galbraith, S.L.; Woodruff, G.N.; McCulloch, J. The relationship between glutamate release and cerebral blood flow after focal cerebral ischemia in the cat: effect of pretreatment with enadoline (a kappa receptor agonist). Brain Res. 1996, 712, 329-334.
19. Tomohiko, K.; Makio, S.; Yasuhiro, O.; Motoo, S.; Ken, M.; Masayoshi, S. ; Kihachi, S.; Sadaaki, M. Morphine prevents peroxynitrite-induced death of human neuroblastoma SH-SY5Y cells through a direct scavenging action. EJP 1999, 372, 319-324.
20. Kim, M.S.; Cheong, Y.P.; So, H.S.; Lee, K.M.; Kim, T.Y.; Oh, J.; Chung, Y.T.; Son, Y.; Kim, B.R.; Park, R. Protective effects of morphine in peroxynitrite-induced apoptosis of primary rat neonatal astrocytes: potential involvement of G protein and PI3 kinase. Biochem. Pharmacol. 2001, 61, 779-786.
21. Alberto, B. Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria. In Method in Enzymology; Sidney, P.C., Nathan, O.K., Eds.; Academic Press, Inc.: New York, 1990; 429-435.
22. Tieze, F. Enzymic method of quantitive determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 1969, 27, 502-522.
23. 2+ overload induced by endogenous excitatory amino acid following glutamate pulse. FEBS lett. 1996, 393, 135-138.
24. Nieminen, A.L.; Petrie, T.G.; Lemasters, J.J.; Selman, W.R. Cyclosporin A delays mitochondrial depolarization induced by NMDA in cortical neurons: evidence of the mitochondrial permeability transition. Neuroscience 1996, 75, 993-997.
25. Schinder, A.F.; Olson, E.C.; Spitzer, N.C.; Monital, M. Mitochondrial dysfunction is a primary event in glutamate neurotoxicity. J. Neurosci. 1996, 16, 6125-6133.
26. White, R.J.; Reynolds, J.J. Mitochondrial depolarization in glutamate-stimulated neurons. J. Neurosci. 1996, 16, 5688-5697.
27. Bannai, S.; Kitamura, E. Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture. J. Biol. Chem. 1980, 255, 2372-2376.
28. Mawatari, K.; Yasui, Y.; Sugitani, K.; Takadera, T.; Kato, S. Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via XC antiporter system. Neuroscience 1996, 73, 201-208.
29. Scanlon, J.M.; Reynolds, I.J. Effects of oxidants and glutamate receptor activation on mitochondrial membrane potential in rat forebrain neurons. J. Neurochem. 1998, 71, 2392-2400.
30. Thor, H.; Moldeus, P.; Orrenius, S. Metabolic activation and hepatotoxicity: effect of cystein, N-acetylcysteine, and methionine on glutathione biosynthesis and bromobenzene toxicity in isolated rat hepatocytes. Arch. Biochem. Biophys. 1979, 192, 405-413.
31. 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J. 1993, 12, 2005-2015.
32. Hoyt, K.R.; Sharma, T.A.; Reynolds, I.J. Trifluoperazine and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurons. Br. J. Pharmacol. 1997, 122, 803-808.
33. Minamikawa, T.; Williams, D.A.; Bowser, D.N.; Nagley, P. Mitochondrial permeability transition and swelling can occur reversibly without inducing cell death in intact human cells. Exp. Cell Res. 1999, 10, 26-37.