Cellular retinol-binding protein-1 expression in normal and fibrotic/cirrhotic human liver: Different patterns of expression in hepatic stellate cells and (myo)fibroblast subpopulations

Journal of Hepatology

Volumn 40, Issue 5, 2004, Pages 774-780

  Lepreux, Sébastien ^a,b   Bioulac Sage, Paulette ^a,b   Gabbiani, Giulio ^c   Sapin, Vincent ^d   Housset, Chantal ^d   Rosenbaum, Jean ^a   Balabaud, Charles ^a   Desmoulière, Alexis ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b HÔPITAL PELLEGRIN   (France)

^c UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^d INSERM   (France)

Author keywords

Biliary epithelial cell; Cellular retinol binding protein 1; Cirrhosis; Fibrosis; Hepatic stellate cell; Liver; Myofibroblast; Portal fibroblast; Smooth muscle actin

Indexed keywords

ALPHA ACTIN; CD34 ANTIGEN; CD68 ANTIGEN; CELLULAR RETINOL BINDING PROTEIN; CELLULAR RETINOL BINDING PROTEIN 1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CELL ACTIVATION; CELL SUBPOPULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KUPFFER CELL; LIVER CELL; LIVER CIRRHOSIS; LIVER FIBROSIS; MALE; MYOFIBROBLAST; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STELLATE CELL;

EID: 1942471045     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2004.01.008     Document Type: Article

References (36)

1. Hendriks H.F., Verhoofstad W.A., Broower A., de Leeuw A.M., Knook D.L. Perisinusoidal fat-storing cells are the main vitamin A storage sites in rat liver. Exp Cell Res. 160:1985;138-149.
2. Blomhoff R., Wake K. Perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis. FASEB J. 5:1991;271-277.
3. Blomhoff R., Rasmussen M., Nilsson A., Norum K., Berg T., Blaner W., et al. Hepatic retinol metabolism. Distribution of retinoids, enzymes, and binding proteins in isolated rat liver cells. J Biol Chem. 260:1985;13560-13565.
4. Xu G., Redard M., Gabbiani G., Neuville P. Cellular retinol-binding protein-1 is transiently expressed in granulation tissue fibroblasts and differentially expressed in fibroblasts cultured from different organs. Am J Pathol. 151:1997;1741-1749.
5. Uchio K., Tuchweber B., Manabe N., Gabbiani G., Rosenbaum J., Desmoulière A. Cellular retinol-binding protein-1 expression and modulation during in vivo and in vitro myofibroblastic differentiation of rat hepatic stellate cells and portal fibroblasts. Lab Invest. 82:2002;619-628.
6. Bhunchet E., Wake K. Role of mesenchymal cell populations in porcine serum-induced rat liver fibrosis. Hepatology. 16:1992;1452-1473.
7. Knittel T., Kobold D., Piscaglia F., Saile B., Neubauer K., Mehde M., Timpl R., et al. Localization of liver myofibroblasts and hepatic stellate cells in normal and diseased rat livers: distinct roles of (myo)fibroblast subpopulations in hepatic tissue repair. Histochem Cell Biol. 112:1999;387-401.
8. Knittel T., Kobold D., Saile B., Grundmann A., Neubauer K., Piscaglia F., Ramadori G. Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential. Gastroenterology. 117:1999;1205-1221.
9. Ramadori G., Saile B. Mesenchymal cells in the liver - one cell type or two? Liver. 22:2002;283-294.
10. Tuchweber B., Desmoulière A., Bochaton-Piallat M., Rubbia-Brandt L., Gabbiani G. Proliferation and phenotypic modulation of portal fibroblasts in the early stages of cholestatic fibrosis in the rat. Lab Invest. 74:1996;265-278.
11. Schmitt-Graff A., Kruger S., Bochard F., Gabbiani G., Denk H. Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers. Am J Pathol. 138:1991;1233-1242.
12. Enzan H., Himeno H., Iwamura S., Saibara T., Onishi S., Yamamoto Y., Hara H. Immunohistochemical identification of Ito cells and their myofibroblastic transformation in adult human liver. Virchows Arch. 424:1994;249-256.
13. Bedossa P., Poynard T. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Hepatology. 24:1996;289-293.
14. Neuville P., Geinoz A., Benzonana G., Redard M., Gabbiani F., Ropraz P., Gabbiani G. Cellular retinol-binding protein-1 is expressed by distinct subsets of rat arterial smooth muscle cells in vitro and in vivo. Am J Pathol. 150:1997;509-521.
15. Skalli O., Ropraz P., Trzeciak A., Benzonana G., Gillessen D., Gabbiani G. A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol. 103:1986;2787-2796.
16. Ballet F., Bouma M.E., Wang S.R., Amit N., Marais J., Infante R. Isolation, culture and characterization of adult human hepatocytes from surgical liver biopsies. Hepatology. 4:1984;849-854.
17. Mennone A., Alvaro D., Cho W., Boyer J.L. Isolation of small polarized bile duct units. Proc Natl Acad Sci USA. 92:1995;6527-6531.
18. Kinnman N., Hultcrantz R., Barbu V., Rey C., Wendum D., Poupon R., Housset C. PDGF-mediated chemoattraction of hepatic stellate cells by bile duct segments in cholestatic liver injury. Lab Invest. 80:2000;697-707.
19. Housset C., Carayon A., Housset B., Legendre C., Hannoun L., Poupon R. Endothelin-1 secretion by human gallbladder epithelial cells in primary culture. Lab Invest. 69:1993;750-755.
20. Sauvant P., Sapin V., Abergel A., Schmidt C.K., Blanchon L., Alexandre-Gouabau M.C., Rosenbaum J., et al. PAV-1, a new rat hepatic stellate cell line converts retinol into retinoic acid, a process altered by ethanol. Int J Biochem Cell Biol. 34:2002;1017-1029.
21. Takase S., Leo M., Nouchi T., Lieber C. Desmin distinguishes cultured fat-storing cells from myofibroblasts, smooth muscle cells and fibroblasts in the rat. J Hepatol. 6:1988;267-276.
22. Yokoi Y., Namihisa T., Kuroda H., Komatsu I., Miyazaki A., Watanabe S., Usui K. Immunocytochemical detection of desmin in fat-storing cells (Ito cells). Hepatology. 4:1984;709-714.
23. Niki T., De Bleser P., Xu G., Van den Berg K., Wisse E., Geerts A. Comparison of glial fibrillary acidic protein and desmin staining in normal and CCl4-induced fibrotic rat liver. Hepatology. 23:1996;1538-1545.
24. Knittel T., Aurish S., Neubauer K., Eichhorst S., Ramadori G. Cell-type-specific expression of neural cell adhesion molecule (N-CAM) in Ito cells of rat liver. Am J Pathol. 149:1996;449-462.
25. Niki T., Pekny M., Hellemans K., Bleser P., Berg K., Vaeyens F., et al. Class VI intermediate filament protein nestin is induced during activation of rat hepatic stellate cells. Hepatology. 29:1999;520-527.
26. Ballardini G., Groff P., Badiali de Giorgi L., Schuppan D., Bianchi F.B. Ito cell heterogeneity: desmin-negative Ito cells in normal rat liver. Hepatology. 19:1994;440-446.
27. Kato M., Kato K., Goodman D. Immunocytochemical studies on the localization of plasma and of cellular retinol-binding proteins and of transthyretin (prealbumin) in rat liver and kidney. J Cell Biol. 98:1984;1696-1704.
28. Cassiman D., Van Pelt J., De Vos R., Van Lommel F., Desmet V., Yap S.H., Roskams T. Synaptophysin: a novel marker for human and rat hepatic stellate cells. Am J Pathol. 155:1999;1831-1839.
29. Cassiman D., Denef C., Desmet V., Roskams T. Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors. Hepatology. 33:2001;148-158.
30. Kawai S., Enzan H., Hayashi Y., Jin Y.L., Guo L.M., Miyazaki E., Toi M., et al. Vinculin: a novel marker for quiescent and activated hepatic stellate cells in human and rat livers. Virchows Arch. 443:2003;78-86.
31. Sztark F., Dubroca J., Latry P., Quinton A., Balabaud C., Bioulac-Sage P. Perisinusoidal cells in patients with normal liver histology. A morphometric study. J Hepatol. 2:1986;358-369.
32. Cassiman D., Libbrecht L., Desmet V., Denef C., Roskams T. Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers. J Hepatol. 36:2002;200-209.
33. Mak K.M., Leo M.A., Lieber C.S. Alcoholic liver injury in baboons: transformation of lipocytes to transitional cells. Gastroenterology. 87:1984;188-200.
34. Schmitt-Gräff A., Ertelt V., Allgaier H.P., Koelble K., Olschewski M., Nitschke R., et al. Cellular retinol-binding protein-1 in hepatocellular carcinoma correlates with beta-catenin. Ki-67 index, and patient survival. Hepatology. 38:2003;470-480.
35. Frolick C.A. Metabolism of retinoids. Sporn M.B., Roberts A.B., Goodman D.E. The retinoids. 1984;177-208 Academic Press, New York, NY.
36. Olson J.A. Vitamin A. Ziegler E.E., Filer L.J. Jr. Present knowledge in nutrition. 7th ed:1996;109-119 International Life Sciences Institute Press, Washington, DC.