GABA Receptors in the Region of the Dorsomedial Hypothalamus of Rats Are Implicated in the Control of Melatonin and Corticosterone Release

Neuroendocrinology

Volumn 63, Issue 1, 1996, Pages 69-78

  Kalsbeek, Andries ^a   Drijfhout, Willem Jan ^c   Westerink, Ben H C ^c   Van Heerikhuize, Joop J ^b   Van de Woude, Tjitske P ^b   Van der Vliet, Jan ^b   Buijs, Ruud M ^b  

^a Netherlands Institute for Brain Research ^*

^b NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Adrenal steroids; Circadian; GABA; Melatonin; Pineal gland; Rhythms; Suprachiasmatic nucleus

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; CORTICOSTERONE; MELATONIN; MUSCIMOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; CORTICOSTERONE RELEASE; GABAERGIC SYSTEM; HORMONE RELEASE; HYPOTHALAMUS; MALE; MICRODIALYSIS; NEUROANATOMY; NEUROPHYSIOLOGY; NEUROTRANSMISSION; NONHUMAN; PINEAL BODY; PRIORITY JOURNAL; RAT; SUPRACHIASMATIC NUCLEUS;

ANIMALS; CIRCADIAN RHYTHM; CORTICOSTERONE; GABA AGONISTS; HYPOTHALAMUS, MIDDLE; MALE; MELATONIN; MUSCIMOL; RATS; RATS, WISTAR; RECEPTORS, GABA; SUPRACHIASMATIC NUCLEUS;

EID: 0030059622     PISSN: 00283835     EISSN: 14230194     Source Type: Journal    
DOI: 10.1159/000126937     Document Type: Article

References (75)

1. Klein DC, Moore RY, Reppert SM: Supra-chiasmatic Nucleus, The Mind's Clock, New York, Oxford University Press, 1991.
2. Reiter RJ: Melatonin: That ubiquitously acting pineal hormone, N Phvs Sci 1991:6:223-227.
3. Wever RA: Light effects on human circadian rhythms: A review of recent Andechs experiments, J Biol Rhythms 1989:4:161-185.
4. Van Cauter E, Sturis J, Byrne MM, Blackman JD, Leproult R, Ofek G, L'llcrmite-Baleriaux M, Refetoff S, Turek FW, Van Recth O: Demonstration of rapid light-induced advances and delays of the human circadian clock using hormonal phase markers, Am J Physiol 1994:266: E953-E963.
5. Klein DC, Smoot R, Weller JL, Higa S, Markcy SP, Creed GJ, Jacobowitz DM: Lesions of the paraventricular nucleus area of the hypothalamus disrupt the suprachiasmalic-spinal cord circuit in the melatonin rhythm generating system, Brain Res Bull 1983:10:647-652.
6. Hastings MH, Herbert J: Ncurotoxic lesions of the paravcntriculo-spinal projection block the nocturnal rise in pineal melatonin synthesis in the Syrian hamster, Neurosci Lett 1986:69:1-6.
7. Bittman EL, Crandell RG, Lehman MN: Influences of the paraventricular and suprachias-matic nuclei and olfactory bulbs on melatonin responses in the golden hamster, Biol Reprod 1989:40:118-126.
8. Lehman MN, Bittman EL, Newman SW: Role of the hypothalamic paraventricular nucleus in neuroendocrine responses to daylength in the golden hamster, Brain Res 1984:308:25-32.
9. Wolfe DE, Potter LT, Richardson KC, Axelrod J: Localizing tritiated norepinephrine in sympathetic axons by electron microscopic autoradiography, Science 1962:138:440-442.
10. Johnson RF, Smale L, Moore RY, Morin LP: Paraventricular nucleus efferents mediating photoperiodism in male golden hamsters, Neurosci Lett 1989:98:85-90.
11. Inouye SIT, Turek FW: Horizontal knife cuts either ventral or dorsal to the hypothalamic paraventricular nucleus block testicular regression in golden hamsters maintained in short days, Brain Res 1986;370:102-107.
12. Pickard GE, Turek FW: The hypothalamic paraventricular nucleus mediates the photo-periodic control of reproduction but not the effects of light on the circadian rhythm of activity, Neurosci Lett 1983:43:67-72.
13. Smalc L, Cassone VM, Moore RY, Morin LP: Paraventricular nucleus projections mediating pineal melatonin and gonadal responses to photoperiod in the hamster, Brain Res Bull 1989:22:263-269.
14. Eskes GA, Rusak B: Horizontal knife cuts in the suprachiasmatic area prevent hamster gonadal responses to photoperiod, Neurosci Lett 1985;61:261-266.
15. Hoomeman EMD, Buijs RM: Vasopressin fiber pathways in the rat brain following suprachiasmatic nucleus lesioning, Brain Res 1982; 243:235-241.
16. Watts AG, Swanson LW: Efferent projections of the suprachiasmatic nucleus, II, Studies using retrograde transport of fluorescent dyes and simultaneous peptide immunohistochemistry in the rat, J Comp Neurol 1987;258:230-252.
17. Kalsbeck A, Teclcmariam-Mesbah R, Pevel P: Efferent projections of the suprachiasmatic nucleus in the golden hamster (Mesocricetus aura-ms), J Comp Neurol 1993;332:293-314.
18. Kalsbeck A, Rikkcrs M, Vivien-Rocls B, Pevet P: Vasopressin and vasoactive intestinal peptide infused in the paraventricular nucleus of the hypothalamus elevate plasma melatonin levels, J Pineal Res 1993;15:46-52.
19. Schröder H, Reuss S, Stehle J, Vollrath L: Intra-arterially administered vasopressin inhibits nocturnal pineal melatonin synthesis in the rat, Comp Biochem Physiol 1988:4:651-653.
20. Schröder H, Stehle J, Möller M: Stimulation of serotonin-N-acetvltransferase activity in the pineal gland of the mongolian gerbil (Meriones ungiiiciilalus) by intracerebroventricular injection of vasoactive intestinal polypeptide, J Pineal Res 1989;7:393-399.
21. Buijs RM, Hou YX, Shinn S, Renaud LP: Ultrastructural evidence for intra-and extranu-clear projections of GABAergic neurons of the suprachiasmatic nucleus, J Comp Neurol 1994; 340:381-391.
22. Martin DS, Segura T, Haywood JR: Cardiovascular responses to Bicucullinc in the paraventricular nuclcus of the rat, Hypertension 1991; 18:48-55.
23. Shekhar A, Sims LS, Bowsher RR: GABA receptors in the region of the dorsomedial hypothalamus of rats regulate anxiety in the elevated plus-maze test, II, Physiological measures, Brain Res 1993;627:17-24.
24. Singewald N, Guo L, Philippu A: Release of endogenous GABA in the posterior hypothalamus of the conscious rat: Effects of drugs and experimentally induced blood pressure changes, Naunyn-Schmiedebergs Arch Pharmacol 1993:347:402-406.
25. Martin DS, Haywood JR: Hemodynamic responses to paraventricular nucleus disinhibi-tion with bicuculline in conscious rats, Am J Physiol 1993;265:H1727-H1733.
26. Waldrop TG, Bauer RM, Iwamoto GA: Microinjection of GABA antagonists into the posterior hypothalamus elicits locomotor activity and a cardiorespiratory activation, Brain Res 1988:444:84-94.
27. Drijfhout WJ, Grol CJ, Westerink BHC: Mi-crodialvsis of melatonin in the rat pineal gland: Methodology and pharmacological applications, J Neurochem 1993;61:936-942.
28. Steffens AB: A method for frequent sampling of blood and continuous infusion of fluids in the rat without disturbing the animal, Physiol Behav 1969:4:833-836.
29. Drijfhout WJ, Grol CJ, Westerink BHC: Microdialysis in the rat pineal gland, monitoring the innervation and hormonal response of a peripheral gland: in Louilot A, Durkin T, Spampinato U, Cador M (cds): Monitoring Molecules in Neuroscience, Proc 6th Int Conf in vivo Methods, Seignosc, 1994, pp 367-368.
30. Dccavel C, Van Den Pol AN: GABA: A dominant neurotransmittcr in the hypothalamus, J Comp Neurol 1990:302:1019-1037.
31. Roland BL, Sawchenko PE: Local origins of sonic GABAergic projections to the paraventricular and supraoptic nuclei of the hypothalamus in the rat, J Comp Neurol 1993:332:123-143.
32. Cullinan WE, Herman JP, Watson SJ: Ventral subicular interaction with the hypothalamic paraventricular nucleus: Evidence for a relay in the bed nucleus of the stria terminalis, J Comp Neurol 1993;332:1-20.
33. Gritti I, Mainville L, Jones BE: Projections of GABAergic and cholinergic basal forcbrain and GABAergic preoptic-anterior hypothalamic neurons to the posterior lateral hypothalamus of the rat, J Comp Neurol 1994:339:251-268.
34. Laakso MJ, Porkka-Hciskancn T, Alila A, Pe-dcr M, Johansson G: Twenty-four-hour patterns of pineal melatonin and pituitary and plasma prolactin in male rats under 'natural' and artificial lighting conditions, Ncurocndo-crinology 1988;48:308-313.
35. Laakso ML, Porkka-Heiskanen T, Alila A, Ka-jandcr S, Stenberg D, Johansson G: Effect of different nocturnal illuminances on melatonin, prolactin, and gonadotropins in male rats, J Pineal Res 1989;7:355-364.
36. Ho AK, Grota IJ, Brown GM: Relationship between pineal N-acetyltransfcrase activity, pineal melatonin and serum melatonin in rats under different lighting conditions, Neuroen-docrinologv 1984:39:465-470.
37. Klein DC, Moore RY: Pineal N-acetvltransfer-asc and hydroxyindolc-o-methyl-transferase: Control by the retinohypothalamic tract and the suprachiasmatic nucleus, Brain Res 1979: 174:245-262.
38. Moore RY, Klein DC: Visual pathways and the central neural control of a circadian rhythm in pineal serotonin N-acetyltransferase activity, Brain Res 1974:71:17-33.
39. Reppert SM, Perlow MJ, Ungerleider LG, Mishkin M, Tamarkin L, OrloffDG, Hoffman HJ, Klein DC: Effects of damage to the suprachiasmatic area of the anterior hypothalamus on the daily melatonin and cortisol rhythms in the rhesus monkey, J Neurosci 1981:1:1414-1425.
40. Tcssonneaud A, Locatelli A, Caldani M, Vi-guicr-Martinez MC: Bilateral lesions of the suprachiasmatic nuclei alter the nocturnal melatonin secretion in sheep, J Neuroendocrinol 1995;7:145-152.
41. Inouyc SIT, Shinohara K, Tominaga K, Takeu-chi J, Nagasaki H, Isobe Y, Fukuhara C, Otori Y, Yang J, Cagampang FRA, Yamazaki S, To-kumasu A: Circadian rhythms in peptides and ihcir precursor messenger RNAs in the supra-chiasmatic nucleus; in Nakagawa H, Oomura Y, Nagai K (eds): New Functional Aspects of the Suprachiasmatic Nucleus of the Hypothalamus, London, Libbey, 1993, pp 219-233.
42. Kanterewicz BI, Bolombek DA, Roscnstein RE, Cardinali DP: Diurnal changes of GABA turnover rate in brain and pineal gland of Syrian hamsters, Brain Res Bull 1993:31:661-666.
43. Cattabeni F, Maggi A, Monduzzi M, De Ange-lis L., Racagni G: GABA: Circadian fluctuations in rat hypothalamus, J Neurochcm 1978: 31:565-567.
44. Aguilar-Roblero R, Vcrduzco-Carbajal L, Rodriguez C, Mcndez-Franco J, Moran J, de la Mora MP: Circadian rhythmicity in the GABAergic system in the suprachiasmatic nuclei of the rat, Ncurosci Lett 1993:157:199-202.
45. Janssen BJA, Tysscn CM, Duindam H, Rict-veld WJ: Suprachiasmatic lesions eliminate 24-h blood pressure variability in rats, Physiol Behav 1994;55:307-311.
46. Warren WS, Champncy TH, Casonc VM: The suprachiasmatic nucleus controls the circadian rhythm of heart rate via the sympathetic nervous system, Physiol Behav 1994:55:1091-1099
47. McIntyre IM, Norman TR, Burrows GD, Ann-strong SM: Alterations to plasma melatonin and cortisol after evening alprazolam administration in humans, Chronobiol lnt 1993; 10: 205-213.
48. Monteleone P, Forziati D, Orazzo C, Maj M: Preliminary observations on the suppression of nocturnal plasma melatonin levels by shortterm administration of diazepam in humans, J Pineal Res 1989:6:253-258.
49. Kabuto M, Namura I, Saitoh Y: Nocturnal enhancement of plasma melatonin could be suppressed by benzodiazepines in humans, Endocrinol Jpn 1986;33:405-414.
50. Allen NHP, Smythe PJ, Martin N, Plaskett E, Osola K, Childs P, Thompson C: The effect of temazepam on melatonin secretion and light sensitivity, J Psychopharmacol 1994;8:94-97.
51. Copinschi G, Van Ondcrbergcn A, L’Hermite-Baleriaux M, Szyper M, Caufriez A, Bosson D, L’Hermitc M, Robyn C, Turek FW, Van Cau-ter E: Effects of the short-acting benzodiazepine Triazolam, taken at bedtime, on circadian and sleep-related hormonal profiles in normal men, Sleep 1990;13:232-244.
52. Morin LP: Neural control of circadian rhythms as revealed through the use of benzodiazepines: in Klein DC, Moore RY, Rcppert SM (eds): Suprachiasmatic Nucleus, The Mind’s Clock, New York, Oxford University Press, 1991, pp 324-338.
53. Van Reeth O, Losee-OIson S, Turek FW: Phase shifts in the circadian activity rhythm induced by triazolam arc not mediated by the eyes or the pineal gland in the hamster, Ncurosci Lett 1987;80:185-190.
54. Zatz M, Brownstein MJ: Central depressants rapidly reduce nocturnal serotonin N-acetyl-transferase activity in the rat pineal gland, Brain Res 1979:160:381-385.
55. Bisset GW, Chowdrcy HS, Fairhall KM, Gunn LK: Central inhibition by gamma-aminobutvr-ic acid and muscimol of the release of vasopressin and oxytocin by an osmotic stimulus in the rat, BrJ Pharmacol 1990;99:529-535.
56. Plotsky PM, Otto S, Sutton S: Neurotransmitter modulation of corticotropin releasing factor secretion into the hypophvsial-portal circulation, Life Sei 1987:41:1311-1317.
57. Willoughby JO, Jervois PM, Menadue MF, Blessing WW: Activation of GABA receptors in the hypothalamus stimulates secretion of growth hormone and prolactin, Brain Res 1986;347:119-125.
58. Mäkinen M, Ahtcc L, Rosenqvist K, Tuomi-nen RK, Männistö P: Effects of intraventricu-lar taurine, homotaurinc and gaba on serum prolactin and thyrotropin levels in female and in male rats, J Neural Transm Gen Sect 1993: 94:155-163.
59. Kalsbeek A, Buijs RM, Van Heerikhuize JJ, Arts M, Van Der Woude TP: Vasoprcssin-con-taining neurons of the suprachiasmatic nuclei inhibit corticosterone release, Brain Res 1992: 580:62-67.
60. Buijs RM, Kalsbeek A, Van Der Woude TP, Van Heerikhuize JJ, Shinn S: Suprachiasmatic nucleus lesion increases corticosterone secretion, Am J Physiol 1993;264:R1186-R1192.
61. Kalsbeek A, Buijs RM: Peptidergic transmitters of the suprachiasmatic nuclei and the control of circadian rhythmicity; in Joosse J, Buijs RM, Tilders FJH (eds): Progress in Brain Research: The Peptidergic Neuron, Amsterdam, Elsevier, 1992, vol 92, pp 321-333.
62. Miguez I, Aldegundc A: Effect of gamma-ami-nobutyric acid on corticosterone secretion: involvement of the noradrenergic system, Life Sei 1990;46:875-880.
63. Jones MT, Gillham B, Altahcr ARH, Nicholson SA, Campbell EA, Watts SM, Thody A: Clinical and experimental studies on the role of GABA in the regulation of ACrH secretion: A review, Psychoneurocndocrinologv 1984:9: 107-123.
64. Makara GB, Stark E: Effect of Gamma-amino-butyric acid (GABA) and GABA antagonist drugs on ACTH release, Neuroendocrinology 1974;16:178-190.
65. Levin MC, Sawchenko PE, Howe PRC, Bloom SR, Polak JM: Organization of galanin-immu-noreactive inputs to the paraventricular nucleus with special reference to their relationship to catccholaminergic affcrents, J Comp Neurol 1987:261:562-582.
66. Tempel DL, Lcibowitz SF: Galanin inhibits insulin and corticosterone release after injection into the PVN, Brain Res 1990:536:353-357.
67. Hooi SC, Mailer DM, Martin JB, Koenig Jl: Galanergic mechanisms are involved in the regulation of corticotropin and thyrotropin secretion in the rat, Endocrinology 1990:127: 2281-2289.
68. Nicot A, Berod A, Gully D, Rowe W, Quirion R, De Kloet ER, Rostenc W: Blockade of neurotensin binding in the rat hypothalamus and of the central action of neurotensin on the hypoihalamic-pituitarv-adrenal axis with non-peptide receptor antagonists, Neurocndocri-nology 1994;59:572-578.
69. Gudelsky GA, Berry SA, Meltzcr HY: Neurotensin activates tuberoinfundibular dopamine neurons and increases serum corticosterone concentrations in the rat, Neuroendocrinology 1989:49:604-609.
70. Rowe W, Viau V, Meancy MJ, Quirion R: Central administration of neurotensin stimulates hypoihalamic-pituitary-adrcnal activity: The paraventricular CRF neuron as a critical site of action, Ann NY Acad Sci 1992;668:365-367.
71. Fuxe K, Agnati LF, Andersson K, Eneroth P, Harfstrand A, Goldstein M, Zoli M: Studies on neurotensin-catecholaminc interactions in the hypothalamus and in the forebrain of the male rat, Neurochcm lnt 1984:6:737-750.
72. Whitnall MH: Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system, Prog Neurobiol 1993:40:573-629.
73. Stobie KM, Wcick RF: Effects of lesions of the suprachiasmatic and paraventricular nuclei on the inhibition of pulsatile luteinizing hormone release by exogenous vasoactivc intestinal peptide in the ovariectomized rat, Neuroendocri-nologv 1990;51:649-657.
74. Van Der Beek EM, Wiegant VM, Van Der Donk HA, Van Den Hurk R, Buijs RM: Lesions of the suprachiasmatic nucleus indicate the presence of a direct vasoactive intestinal polypeptide-containing projection to gonadotrophin-releasing hormone neurons in the female rat, J Neuroendocrinol 1993:5:137-144.
75. Van Der Beek EM, Van Oudheusen HJC, Buijs RM, Van Der Donk HA, Van Den Hurk R, Wiegam VM: Preferential induction of c-Jos immunoreactivity in vasoactive intestinal pol-ypep:ide-innervated gonadotropin-releasing hormone neurons during a steroid-induced luteinizing hormone surge in the female rat, Endocrinology 1994;134:2636-2644.