A new southwestern chemistry-based ELISA for detection of aryl hydrocarbon receptor transformation: Application to the screening of its receptor agonists and antagonists

Journal of Immunological Methods

Volumn 287, Issue 1-2, 2004, Pages 187-201

  Fukuda, Itsuko ^a   Nishiumi, Shin ^a   Yabushita, Yoshiyuki ^a   Mukai, Rie ^a   Kodoi, Rie ^a   Hashizume, Kaoru ^b   Mizuno, Masashi ^a   Hatanaka, Yutaka ^a,b   Ashida, Hitoshi ^a  

^a KOBE UNIVERSITY   (Japan)

^b DakoCytomation Co Ltd   (Japan)

Author keywords

AhR; AhR nuclear translocator; Arnt; Aryl hydrocarbon receptor; Dioxin responsive element; Dioxins; DRE; ELISA; HAH; Hapten antibody; Southwestern chemistry; Southwestern chemistry based enzyme linked immunosorbent assay; SW ELISA

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON; AROMATIC HYDROCARBON RECEPTOR; DIOXIN; FLAVANOID; FLUORESCEIN ISOTHIOCYANATE;

ANALYTIC METHOD; ARTICLE; CHEMICAL ANALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT;

ANIMALS; ANTIBODIES; BLOTTING, SOUTHWESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; HYDROCARBONS, HALOGENATED; POLYCYCLIC HYDROCARBONS, AROMATIC; RECEPTORS, ARYL HYDROCARBON; SENSITIVITY AND SPECIFICITY;

EID: 1942455860     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2004.02.003     Document Type: Article

References (48)

1. Asaka Y., Watanabe J., Kanamura S. Localization of xenobiotic-responsive element binding protein in rat hepatocyte nuclei after methylcholanthrene administration as revealed by in situ southwestern hybridization. J. Histochem. Cytochem. 46:1998;825.
2. Ashida H., Fukuda I., Yamashita T., Kanazawa K. Flavones and flavonols at dietary levels inhibit a transformation of aryl hydrocarbon receptor induced by dioxin. FEBS Lett. 476:2000;213.
3. Ball H.J., Finlay D. Diagnostic application of monoclonal antibody (MAb)-based sandwich ELISAs. Methods Mol. Biol. 104:1998;127.
4. Behnisch P.A., Hosoe K., Sakai S. Bioanalytical screening methods for dioxin-like compounds: a review of bioassay/biomarker technology. Environ. Int. 27:2001;413.
5. Castillo L., Milano G., Santini J., Demard F., Pierrefite V. Analysis of retinoic acid receptor beta expression in normal and malignant laryngeal mucosa by a sensitive and routine applicable reverse transcription-polymerase chain reaction enzyme-linked immunosorbent assay method. Clin. Cancer Res. 3:1997;2137.
6. Clement R.E. Ultratrace dioxin and dibenzofuran analysis: thirty years of advances. Anal. Chem. 63:1991;1130.
7. Davis D., Safe S. Dose-response immunotoxicities of commercial polychlorinated biphenyls (PCBs) and their interaction with 2,3,7,8- tetrachlorodibenzo-p-dioxin. Toxicol. Lett. 48:1989;35.
8. Davis D., Safe S. Immunosuppressive activities of polychlorinated biphenyls in C57BL/6N mice: structure-activity relationships as Ah receptor agonists and partial antagonists. Toxicology. 63:1990;97.
9. Denison M.S., Fisher J.M., Whitlock J.P. Jr. Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer. Proc. Natl. Acad. Sci. U. S. A. 85:1988;2528.
10. Denison M.S., Fisher J.M., Whitlock J.P. Jr. The DNA recognition site for the dioxin-Ah receptor complex: nucleotide sequence and functional analysis. J. Biol. Chem. 263:1988;17221.
11. Denison M.S., Yao E.F. Characterization of the interaction of transformed rat hepatic cytosolic Ah receptor with a dioxin responsive transcriptional enhancer. Arch. Biochem. Biophys. 284:1991;158.
12. Denison M.S., Phelan D., Elferink C.J. The Ah receptor signal transduction pathway. Denison M.S., Helferich W.G. Toxicant-Receptor Interactions. 1998;3 Taylor and Francis, Philadelphia.
13. De Vito M.J., Birnbaum L.S. Toxicology of the dioxins and related chemicals. Schecter A. Dioxins and Health. 1994;139 Plenum, New York.
14. El-Fouly M.H., Richter J.P., Giesy J.P., Denison M.S. Production of a novel recombinant cell line for use as a bioassay system for detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. Environ. Toxicol. Chem. 13:1994;1581.
15. Ferrario J., Byrne C., McDaniel D., Dupuy A.E. Jr., Harless R. Determination of 2,3,7,8-chlorine-substituted dibenzo-p-dioxins and -furans at the part per trillion level in United States beef fat using high-resolution gas chromatography/high-resolution mass spectrometry. Anal. Chem. 68:1996;647.
16. Ferrario J., Byrne C., McDaniel D., Dupuy A.E. Jr. Background contamination by coplanar polychlorinated biphenyls (PCBs) in trace level high-resolution gas chromatography/high-resolution mass spectrometry (HRGC/HRMS) analytical procedures. Chemosphere. 34:1997;2451.
17. Garrison P.M., Tullis K., Aarts J.M.M.J.G., Brouwer A., Giesy J.P., Denison M.S. Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. Fundam. Appl. Toxicol. 30:1996;194.
18. Giesy J.P., Ludwig J.P., Tillitt D.E. Dioxins, dibenzofurans, PCBs and colonial fish-eating water birds. Schecter A. Dioxins and Health. 1994;249 Plenum, New York.
19. Hankinson O. The aryl hydrocarbon receptor complex. Annu. Rev. Pharmacol. Toxicol. 35:1995;307.
20. Hashimoto T., Furuyashiki T., Sano T., Kihara K., Fukuda I., Ito W., Park P., Kanazawa K., Danno G., Ashida H. Apoptosis in the thymus after intraperitoneal injection of rats with Trp-P-1. Environ. Mol. Mutagen. 40:2002;175.
21. Heath-Pagliuso S., Rogers W.J., Tullis K., Seidel S.D., Cenijn P.H., Brouwer A., Denison M.S. Activation of the Ah receptor by tryptophan and tryptophan metabolites. Biochemistry. 37:1998;11508.
22. Helferich W.G., Denison M.S. Ultraviolet photoproducts of tryptophan can act as dioxin agonists. Mol. Pharmacol. 40:1991;674.
23. Kinoshita N., Suzuki S., Matsuda Y., Taniguchi N. Alpha-fetoprotein antibody-lectin enzyme immunoassay to characterize sugar chains for the study of liver diseases. Clin. Chim. Acta. 179:1989;143.
24. Koji T., Komuta K., Nozawa M., Yamada S., Nakane P.K. Localization of cyclic adenosine 3′,5′-monophosphate-responsive element (CRE)-binding proteins by southwestern histochemistry. J. Histochem. Cytochem. 42:1994;1399.
25. Korkalainen M., Tuomisto J., Pohjanvirta R. The Ah receptor of the most dioxin-sensitive species, guinea pig, is highly homologous to the human Ah receptor. Biochem. Biophys. Res. Commun. 285:2001;1121.
26. Lee J.-E., Safe S. 3′,4′-Dimethoxyflavone as an aryl hydrocarbon receptor antagonist in human breast cancer cells. Toxicol. Sci. 58:2000;235.
27. Lusska A., Shen E., Whitlock J.P. Jr. Protein-DNA interactions at a dioxin-responsive enhancer. J. Biol. Chem. 268:1993;6575.
28. Nagy S.R., Sanborn J.R., Hammock B.D., Denison M.S. Development of a green fluorescent protein-based cell bioassay for the rapid and inexpensive detection and characterization of Ah receptor agonists. Toxicol. Sci. 65:2002;200.
29. Nagy S.R., Liu G., Lam K.S., Denison M.S. Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay. Biochemistry. 41:2002;861.
30. Nelson D.R., Kamataki T., Waxman D.J., Guengerich F.P., Estabrook R.W., Feyereisen R., Gonzales F.J., Coon M.J., Gunsalus I.C., Gotoh O., Okuda K., Nebert D.W. The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes and nomenclature. DNA Cell Biol. 12:1993;1.
31. Phelan D., Winter G.M., Rogers W.J., Lam J.C., Denison M.S. Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin. Arch. Biochem. Biophys. 357:1998;155.
32. Poland A., Knutson J.C. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22:1982;517.
33. Probst M.R., Reisz-Porszasz S., Agbunag R.V., Ong M.S., Hankinson O. Role of the aryl hydrocarbon receptor nuclear translocator protein in aryl hydrocarbon (dioxin) receptor action. Mol. Pharmacol. 44:1993;511.
34. Richter C.A., Tieber V.L., Denison M.S., Giesy J.P. An in vitro rainbow trout cell bioassay for aryl hydrocarbon receptor-mediated toxins. Environ. Toxicol. Chem. 16:1997;543.
35. Safe S.H. Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). CRC Crit. Rev. Toxicol. 21:1990;51.
36. Safe S.H. Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. CRC Crit. Rev. Toxicol. 24:1994;87.
37. Seidel S.D., Li V., Winter G.M., Rogers W.J., Martinez E.I., Denison M.S. Ah receptor-based chemical screening bioassays: application and limitations for the detection of Ah receptor agonists. Toxicol. Sci. 55:2000;107.
38. Stephens R.D., Rappe C., Hayward D.G., Nygren M., Startin J., Esboll A., Carle J., Yrjanheikki E.J. World Health Organization international intercalibration study on dioxins and furans in human milk and blood. Anal. Chem. 64:1992;3109.
39. Tanabe S., Kannan N., Subramanian A., Watanabe S., Tatsukawa R. High toxic PCBs: occurrence, source persistency and toxic implications to wildlife and humans. Environ. Pollut. 27:1987;147.
40. Van den Berg M., Birnbaum L., Bosveld A.T.C., Brunström B., Cook P., Feeley M., Giesy J.P., Hanberg A., Hasegawa R., Kennedy A.W., Kubiak T., Larsen J.C., Rolaf van Leeuwen F.X., Liem A.K.D., Nolt C., Peterson R.E., Poellinger L., Safe S., Schrenk D., Tillitt D., Tysklind M., Younes M., Waern F., Zacharewski T. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for human and wildlife. Environ. Health Perspect. 106:1998;775.
41. Versteeg H.H., Nijhuis E., van den Brink G.R., Evertzen M., Pynaert G.N., van Deventer S.J., Coffer P.J., Peppelenbosch M.P. A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein. Biochem. J. 350:2000;717.
42. Voller A., Bartlett A., Bidwell D.E. Enzyme immunoassays with special reference to ELISA techniques. J. Clin. Pathol. 31:1978;507.
43. Webster T., Commoner B. The dioxin debate. Schecter A. Dioxins and Health. 1994;1 Plenum, New York.
44. Wheelock G.D., Hurst K.R., Babish J.G. Bioimmunoassay of aryl hydrocarbon (Ah) receptor transformation in vitro by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol. Methods. 6:1996;41.
45. Whitlock J.P. Jr. Genetic and molecular aspects of 2,3,7,8- tetrachlorodibenzo-p-dioxin action. Annu. Rev. Pharmacol. Toxicol. 30:1990;251.
46. Whitlock J.P. Jr. Mechanistic aspects of dioxin action. Chem. Res. Toxicol. 6:1993;745.
47. Zhou J.-G., Henry E.C., Palermo C.M., Dertinger S.D., Gasiewicz T.A. Species-specific transcriptional activity of synthetic flavonoids in guinea pig and mouse cells as a result of differential activation of the aryl hydrocarbon receptor to interact with dioxin-responsive elements. Mol. Pharmacol. 63:2003;915.
48. Zhu Z., Andrisani O.M., Pot D.A., Dixon J.E. Purification and characterization of a 43-kDa transcription factor required for rat somatostatin gene expression. J. Biol. Chem. 264:1989;6550.