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Volumn 38, Issue 2, 2004, Pages 285-297

Molecular cloning of the potato Gro1-4 gene conferring resistance to pathotype Ro1 of the root cyst nematode Globodera rostochiensis, based on a candidate gene approach

Author keywords

Candidate gene family; Globodera rostochiensis; Nematodes; Resistance gene; Solanum tuberosum

Indexed keywords

AMINO ACIDS; CROPS; CULTIVATION; GENES; PLANTS (BOTANY);

EID: 1942443113     PISSN: 09607412     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-313X.2004.02047.x     Document Type: Article
Times cited : (192)

References (50)
  • 1
    • 0028973128 scopus 로고
    • Marker enrichment and high-resolution map of the segment of potato chromosome VII harbouring the nematode resistance gene Gro1
    • Ballvora, A., Hesselbach, J., Niewöhner, J., Leister, D., Salamini, F. and Gebhardt, C. (1995) Marker enrichment and high-resolution map of the segment of potato chromosome VII harbouring the nematode resistance gene Gro1. Mol. Gen. Genet. 249, 82-90.
    • (1995) Mol. Gen. Genet. , vol.249 , pp. 82-90
    • Ballvora, A.1    Hesselbach, J.2    Niewöhner, J.3    Leister, D.4    Salamini, F.5    Gebhardt, C.6
  • 2
    • 0036112532 scopus 로고    scopus 로고
    • The R1 gene for potato resistance to late blight (Phytophthora infestans) belongs to the leucine zipper/NBS/LRR class of plant resistance genes
    • Ballvora, A., Ercolano, M.R., Weiß, J., Meksem, K., Bormann, C.A., Oberhagemann, P., Salamini, F. and Gebhardt C. (2002) The R1 gene for potato resistance to late blight (Phytophthora infestans) belongs to the leucine zipper/NBS/LRR class of plant resistance genes. Plant J. 30, 361-371.
    • (2002) Plant J. , vol.30 , pp. 361-371
    • Ballvora, A.1    Ercolano, M.R.2    Weiß, J.3    Meksem, K.4    Bormann, C.A.5    Oberhagemann, P.6    Salamini, F.7    Gebhardt, C.8
  • 3
    • 0025606334 scopus 로고
    • Localization by restriction fragment length polymorphism mapping in potato of a major dominant gene conferring resistance to the potato cyst nematode Globodera rostochiensis
    • Barone, A., Ritter, E., Schachtschnabel, U., Debener, T., Salamini, F. and Gebhardt, C. (1990) Localization by restriction fragment length polymorphism mapping in potato of a major dominant gene conferring resistance to the potato cyst nematode Globodera rostochiensis. Mol. Gen. Genet. 224, 177-182.
    • (1990) Mol. Gen. Genet. , vol.224 , pp. 177-182
    • Barone, A.1    Ritter, E.2    Schachtschnabel, U.3    Debener, T.4    Salamini, F.5    Gebhardt, C.6
  • 4
    • 0033133572 scopus 로고    scopus 로고
    • The Rx gene from potato controls separate virus resistance and cell death responses
    • Bendahmane, A., Kanyuka, K. and Baulcombe, D.C. (1999) The Rx gene from potato controls separate virus resistance and cell death responses. Plant Cell, 11, 781-791.
    • (1999) Plant Cell , vol.11 , pp. 781-791
    • Bendahmane, A.1    Kanyuka, K.2    Baulcombe, D.C.3
  • 6
    • 0032202153 scopus 로고    scopus 로고
    • Three genes of the Arabidopsis RPP1 complex resistance locus recognize distinct Peronospora parasitica avirulence determinants
    • Botella, M.A., Parker, J.E., Frost, L.N., Bittner-Eddy, P.D., Beynon, J.L, Daniels, M.J., Holub, E.B. and Jones, J.D.G. (1998) Three genes of the Arabidopsis RPP1 complex resistance locus recognize distinct Peronospora parasitica avirulence determinants. Plant Cell, 10, 1847-1860.
    • (1998) Plant Cell , vol.10 , pp. 1847-1860
    • Botella, M.A.1    Parker, J.E.2    Frost, L.N.3    Bittner-Eddy, P.D.4    Beynon, J.L.5    Daniels, M.J.6    Holub, E.B.7    Jones, J.D.G.8
  • 7
    • 0001667978 scopus 로고
    • An isozyme marker for resistance to race 3 of Fusarium oxysporum f. sp. lycopersici in tomato
    • Bournival, B.L., Vallejos, C.E. and Scott, J.W. (1989) An isozyme marker for resistance to race 3 of Fusarium oxysporum f. sp. lycopersici in tomato. Theor. Appl. Genet. 78, 489-494.
    • (1989) Theor. Appl. Genet. , vol.78 , pp. 489-494
    • Bournival, B.L.1    Vallejos, C.E.2    Scott, J.W.3
  • 8
    • 0031853175 scopus 로고    scopus 로고
    • Identification of AFLP and SSR markers associated with quantitative resistance to Globodera pallida (Stone) in tetraploid potato (Solanum tuberosum subsp. tuberosum) with a view to marker-assisted selection
    • Bradshaw, J.E., Hackett, C.A., Meyer, R.C., Milbourne, D., McNicol, J.W., Phillips, M.S. and Waugh, R. (1998) Identification of AFLP and SSR markers associated with quantitative resistance to Globodera pallida (Stone) in tetraploid potato (Solanum tuberosum subsp. tuberosum) with a view to marker-assisted selection. Theor. Appl. Genet. 97, 202-210.
    • (1998) Theor. Appl. Genet. , vol.97 , pp. 202-210
    • Bradshaw, J.E.1    Hackett, C.A.2    Meyer, R.C.3    Milbourne, D.4    McNicol, J.W.5    Phillips, M.S.6    Waugh, R.7
  • 9
    • 0004215796 scopus 로고
    • Nematode parasites of potato
    • (Nickle, W.R., ed.). New York: Marcel Dekker
    • Brodie, B.B. (1984) Nematode parasites of potato. In Plant and Insect Nematodes (Nickle, W.R., ed.). New York: Marcel Dekker, pp. 167-212.
    • (1984) Plant and Insect Nematodes , pp. 167-212
    • Brodie, B.B.1
  • 10
    • 0032701034 scopus 로고    scopus 로고
    • Classical and molecular approaches for managing nematodes affecting potato
    • Brodie, B.B. (1999) Classical and molecular approaches for managing nematodes affecting potato. Can. J. Plant Pathol. 21, 222-230.
    • (1999) Can. J. Plant Pathol. , vol.21 , pp. 222-230
    • Brodie, B.B.1
  • 11
    • 14444268507 scopus 로고    scopus 로고
    • Positional cloning of a gene for nematode resistance in sugar beet
    • Cai, D., Kleine, M., Kifle, S. et al. (1997) Positional cloning of a gene for nematode resistance in sugar beet. Science, 275, 832-834.
    • (1997) Science , vol.275 , pp. 832-834
    • Cai, D.1    Kleine, M.2    Kifle, S.3
  • 12
    • 0035859020 scopus 로고    scopus 로고
    • Plant pathogens and integrated defence responses to infection
    • Dangl, J.L. and Jones, J.D.G. (2001) Plant pathogens and integrated defence responses to infection. Nature, 411, 826-833.
    • (2001) Nature , vol.411 , pp. 826-833
    • Dangl, J.L.1    Jones, J.D.G.2
  • 13
    • 0036320058 scopus 로고    scopus 로고
    • The broad-spectrum potato cyst nematode resistance gene (Hero) from tomato is the only member of a large gene family of NBS-LRR genes with an unusual amino acid repeat in the LRR region
    • Ernst, K., Kumar, A., Kriseleit, D., Kloos, D.-U., Phillips, M.S. and Ganal, M.W. (2002) The broad-spectrum potato cyst nematode resistance gene (Hero) from tomato is the only member of a large gene family of NBS-LRR genes with an unusual amino acid repeat in the LRR region. Plant J. 31, 127-136.
    • (2002) Plant J. , vol.31 , pp. 127-136
    • Ernst, K.1    Kumar, A.2    Kriseleit, D.3    Kloos, D.-U.4    Phillips, M.S.5    Ganal, M.W.6
  • 14
    • 0003319272 scopus 로고
    • The origin and distribution of the golden nematode and its potential in the U.S.A.
    • Evans, K. and Brodie, B.B. (1980) The origin and distribution of the golden nematode and its potential in the U.S.A. Am. Potato J. 57, 79-89.
    • (1980) Am. Potato J. , vol.57 , pp. 79-89
    • Evans, K.1    Brodie, B.B.2
  • 15
    • 0001994721 scopus 로고
    • Pest aspects of potato production. Part 1. The nematode pests of potatoes
    • (Harris, P., ed.). London: Chapman & Hall
    • Evans, K. and Trudgill, D.L. (1992) Pest aspects of potato production. Part 1. The nematode pests of potatoes. In The Potato Crop, 2nd edn (Harris, P., ed.). London: Chapman & Hall, pp. 438-475.
    • (1992) The Potato Crop, 2nd Edn , pp. 438-475
    • Evans, K.1    Trudgill, D.L.2
  • 16
    • 0034792463 scopus 로고    scopus 로고
    • Organization of genes controlling disease resistance in the potato genome
    • Gebhardt, C. and Valkonen, J.P.T. (2001) Organization of genes controlling disease resistance in the potato genome. Annu. Rev. Phytopathol. 39, 79-102.
    • (2001) Annu. Rev. Phytopathol. , vol.39 , pp. 79-102
    • Gebhardt, C.1    Valkonen, J.P.T.2
  • 18
    • 0032918558 scopus 로고    scopus 로고
    • Plant cis-acting regulatory DNA elements (PLACE) database: 1999
    • Higo, K., Ugawa, Y., Iwamoto, M., and Korenaga, T. (1999) Plant cis-acting regulatory DNA elements (PLACE) database: 1999. Nucl. Acids Res. 27, 297-300.
    • (1999) Nucl. Acids Res. , vol.27 , pp. 297-300
    • Higo, K.1    Ugawa, Y.2    Iwamoto, M.3    Korenaga, T.4
  • 20
    • 77956742948 scopus 로고    scopus 로고
    • The role of leucine-rich repeat proteins in plant defense
    • Jones, D.A. and Jones, J.D.G. (1997) The role of leucine-rich repeat proteins in plant defense. Adv. Bot. Res. 24, 89-167.
    • (1997) Adv. Bot. Res. , vol.24 , pp. 89-167
    • Jones, D.A.1    Jones, J.D.G.2
  • 21
    • 0026951225 scopus 로고
    • Effective vectors for transformation, expression of heterologous genes, and assaying transposon excision in transgenic plants
    • Jones, J.D.G., Shlumukov, L., Carland, F., English, J., Scofield, S.R., Bishop, G.J. and Harrison, K. (1992) Effective vectors for transformation, expression of heterologous genes, and assaying transposon excision in transgenic plants. Transgenic Res. 1, 285-297.
    • (1992) Transgenic Res. , vol.1 , pp. 285-297
    • Jones, J.D.G.1    Shlumukov, L.2    Carland, F.3    English, J.4    Scofield, S.R.5    Bishop, G.J.6    Harrison, K.7
  • 22
    • 0025792297 scopus 로고
    • Structural features in eukaryotic mRNAs that modulate the initiation of translation
    • Kozak, M. (1991) Structural features in eukaryotic mRNAs that modulate the initiation of translation. J. Biol. Chem. 266, 19867-19870.
    • (1991) J. Biol. Chem. , vol.266 , pp. 19867-19870
    • Kozak, M.1
  • 23
    • 0029844894 scopus 로고    scopus 로고
    • A PCR-based approach for isolating pathogen resistance genes from potato with potential for wide application in plants
    • Leister, D., Ballvora, A., Salamini, F. and Gebhardt, C. (1996) A PCR-based approach for isolating pathogen resistance genes from potato with potential for wide application in plants. Nat. Genet. 14, 421-429.
    • (1996) Nat. Genet. , vol.14 , pp. 421-429
    • Leister, D.1    Ballvora, A.2    Salamini, F.3    Gebhardt, C.4
  • 24
    • 0028274821 scopus 로고
    • Quantitative resistance to Phytophthora infestans in potato: A case study for QTL mapping in an allogamous plant species
    • Leonards-Schippers, C., Gieffers, W., Schäfer-Pregl, R., Ritter, E., Knapp, S.J., Salamini, F. and Gebhardt, C. (1994) Quantitative resistance to Phytophthora infestans in potato: a case study for QTL mapping in an allogamous plant species. Genetics, 137, 67-77.
    • (1994) Genetics , vol.137 , pp. 67-77
    • Leonards-Schippers, C.1    Gieffers, W.2    Schäfer-Pregl, R.3    Ritter, E.4    Knapp, S.J.5    Salamini, F.6    Gebhardt, C.7
  • 25
    • 0037753391 scopus 로고
    • Worldwide distribution of potato-cyst nematodes and their importance in crop production
    • Mai, W.F. (1977) Worldwide distribution of potato-cyst nematodes and their importance in crop production. J. Nematol. 9, 30-34.
    • (1977) J. Nematol. , vol.9 , pp. 30-34
    • Mai, W.F.1
  • 26
    • 0031154028 scopus 로고    scopus 로고
    • Retrotransposon insertion into the maize waxy gene results in tissue-specific RNA processing
    • Marillonnet, S. and Wessler, S.R. (1997) Retrotransposon insertion into the maize waxy gene results in tissue-specific RNA processing. Plant Cell, 9, 967-978.
    • (1997) Plant Cell , vol.9 , pp. 967-978
    • Marillonnet, S.1    Wessler, S.R.2
  • 27
    • 0031716027 scopus 로고    scopus 로고
    • A simple method for the production of highly competent cells of Agrobacterium for transformation via electroporation
    • McCormac, A.C., Elliott, M.C. and Chen, D.F. (1998) A simple method for the production of highly competent cells of Agrobacterium for transformation via electroporation. Mol. Biotechnol. 9, 155-159.
    • (1998) Mol. Biotechnol. , vol.9 , pp. 155-159
    • McCormac, A.C.1    Elliott, M.C.2    Chen, D.F.3
  • 28
    • 0033792906 scopus 로고    scopus 로고
    • Two large-insert soybean genomic libraries constructed in a binary vector: Applications in chromosome walking and genome wide physical mapping
    • Meksem, K., Zobrist, K., Ruben, E., Hyten, D., Quanzhou, T., Zhang, H.-B. and Lightfoot, D.A. (2000) Two large-insert soybean genomic libraries constructed in a binary vector: applications in chromosome walking and genome wide physical mapping. Theor. Appl. Genet. 101, 747-755.
    • (2000) Theor. Appl. Genet. , vol.101 , pp. 747-755
    • Meksem, K.1    Zobrist, K.2    Ruben, E.3    Hyten, D.4    Quanzhou, T.5    Zhang, H.-B.6    Lightfoot, D.A.7
  • 29
    • 0032144421 scopus 로고    scopus 로고
    • The root knot nematode resistance gene Mi from tomato is a member of the leucine zipper, nucleotide binding, leucine-rich repeat family of plant genes
    • Milligan, S.B., Bodeau, J., Yaghoobi, J., Kaloshian, I., Zabel, P. and Williamson, V.M. (1998) The root knot nematode resistance gene Mi from tomato is a member of the leucine zipper, nucleotide binding, leucine-rich repeat family of plant genes. Plant Cell, 10, 1307-1319.
    • (1998) Plant Cell , vol.10 , pp. 1307-1319
    • Milligan, S.B.1    Bodeau, J.2    Yaghoobi, J.3    Kaloshian, I.4    Zabel, P.5    Williamson, V.M.6
  • 30
    • 0027989564 scopus 로고
    • The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats
    • Mindrinos, M., Katagiri, F., Yu, G.-L. and Ausubel, F.M. (1994) The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats. Cell, 78, 1089-1099.
    • (1994) Cell , vol.78 , pp. 1089-1099
    • Mindrinos, M.1    Katagiri, F.2    Yu, G.-L.3    Ausubel, F.M.4
  • 32
    • 84982358134 scopus 로고
    • A revised medium for rapid growth and bioassay with tobacco tissue culture
    • Murashige, T. and Skoog, F. (1962) A revised medium for rapid growth and bioassay with tobacco tissue culture. Plant Physiol. 15, 473-479.
    • (1962) Plant Physiol. , vol.15 , pp. 473-479
    • Murashige, T.1    Skoog, F.2
  • 34
    • 0034014008 scopus 로고    scopus 로고
    • Comparative genetics of NBS-LRR resistance gene homologues in the genomes of two dicotyledons: Tomato and Arabidopsis
    • Pan, Q., Liu, Y.-S., Budai-Hadrian, O., Sela, M., Carmel-Goren, L., Zamir, D. and Fluhr, R. (2000) Comparative genetics of NBS-LRR resistance gene homologues in the genomes of two dicotyledons: tomato and Arabidopsis. Genetics, 155, 309-322.
    • (2000) Genetics , vol.155 , pp. 309-322
    • Pan, Q.1    Liu, Y.-S.2    Budai-Hadrian, O.3    Sela, M.4    Carmel-Goren, L.5    Zamir, D.6    Fluhr, R.7
  • 35
    • 0032210884 scopus 로고    scopus 로고
    • Identification of tomato Lhc promoter regions necessary for circadian expression
    • Piechulla, B., Merforth, N. and Rudolph, B. (1998) Identification of tomato Lhc promoter regions necessary for circadian expression. Plant Mol. Biol. 38, 655-662.
    • (1998) Plant Mol. Biol. , vol.38 , pp. 655-662
    • Piechulla, B.1    Merforth, N.2    Rudolph, B.3
  • 36
    • 0002534261 scopus 로고
    • Both developmental and metabolic signals activate the promoter of a class I patatin gene
    • Rocha-Sosa, M., Sonnewald, U., Frommer, W., Stratmann, M., Schell, J. and Willmitzer, L. (1989) Both developmental and metabolic signals activate the promoter of a class I patatin gene. EMBO J. 8, 23-29.
    • (1989) EMBO J. , vol.8 , pp. 23-29
    • Rocha-Sosa, M.1    Sonnewald, U.2    Frommer, W.3    Stratmann, M.4    Schell, J.5    Willmitzer, L.6
  • 37
    • 0003013196 scopus 로고
    • Über die Vererbung der Resistenz gegen den Kartoffelnematoden (Heterodera rostochiensis Woll.) in Kreuzungen von Solanum famatinae Bitt. et Wittm. mit Solanum tuberosum L. und mit S. chacoense Bitt
    • Ross, H. (1962) Über die Vererbung der Resistenz gegen den Kartoffelnematoden (Heterodera rostochiensis Woll.) in Kreuzungen von Solanum famatinae Bitt. Et Wittm. mit Solanum tuberosum L. und mit S. chacoense Bitt. Der Züchter, 32, 74-80.
    • (1962) Der Züchter , vol.32 , pp. 74-80
    • Ross, H.1
  • 38
    • 0001966685 scopus 로고
    • Potato breeding: Problems and perspectives
    • Horn, W. and Röbbelen, G., eds.
    • Ross, H. (1986) Potato breeding: problems and perspectives. (Horn, W. and Röbbelen, G., eds.) J. Plant. Breed. (Suppl. 13).
    • (1986) J. Plant. Breed. , Issue.13 SUPPL.
    • Ross, H.1
  • 40
    • 0025048136 scopus 로고
    • The P-loop - A common motif in ATP- and GTP-binding proteins
    • Saraste, M., Sibbald, P.R. and Wittinghofer, A. (1990) The P-loop - a common motif in ATP- and GTP-binding proteins. Trends Biochem. Sci. 15, 430-434.
    • (1990) Trends Biochem. Sci. , vol.15 , pp. 430-434
    • Saraste, M.1    Sibbald, P.R.2    Wittinghofer, A.3
  • 41
    • 0001934460 scopus 로고
    • RFLP mapping of I1, a new locus in tomato conferring resistance against Fusarium oxysporum f. sp. lycopersici race 1
    • Sarfatti, M., Abu-Abied, M., Katan, J. and Zamir, D. (1991) RFLP mapping of I1, a new locus in tomato conferring resistance against Fusarium oxysporum f. sp. lycopersici race 1. Theor. Appl. Genet. 82, 22-26.
    • (1991) Theor. Appl. Genet. , vol.82 , pp. 22-26
    • Sarfatti, M.1    Abu-Abied, M.2    Katan, J.3    Zamir, D.4
  • 42
    • 0027731047 scopus 로고
    • Plant-nematode interactions
    • Sijmons, P.C. (1993) Plant-nematode interactions. Plant Mol. Biol. 23, 917-931.
    • (1993) Plant Mol. Biol. , vol.23 , pp. 917-931
    • Sijmons, P.C.1
  • 43
    • 0000719012 scopus 로고
    • Arabidopsis thaliana as a new model host for plant-parasitic nematodes
    • Sijmons, P.C., Grundler, F.M.W., von Mende, N., Burrows, P.R. and Wyss, U. (1991) Arabidopsis thaliana as a new model host for plant-parasitic nematodes. Plant J. 1, 245-254.
    • (1991) Plant J. , vol.1 , pp. 245-254
    • Sijmons, P.C.1    Grundler, F.M.W.2    Von Mende, N.3    Burrows, P.R.4    Wyss, U.5
  • 44
    • 1942446655 scopus 로고
    • Potato root eelworm
    • (Southey, J.F, ed.). Norwich: Ministry of Agriculture, Fisheries and Food, Her Majesty's Stationery Office, Technical Bulletin 7
    • Southey, J.F. (1965) Potato root eelworm. In Plant Nematology, 2nd edn (Southey, J.F, ed.). Norwich: Ministry of Agriculture, Fisheries and Food, Her Majesty's Stationery Office, pp. 171-188 (Technical Bulletin 7).
    • (1965) Plant Nematology, 2nd Edn , pp. 171-188
    • Southey, J.F.1
  • 45
    • 0032159287 scopus 로고    scopus 로고
    • The two genes encoding starch-branching enzymes IIa and IIb are differentially expressed in barley
    • Sun, C., Sathish, P., Ahlandsberg, S. and Jansson, C. (1998) The two genes encoding starch-branching enzymes IIa and IIb are differentially expressed in barley. Plant Physiol. 118, 37-49.
    • (1998) Plant Physiol. , vol.118 , pp. 37-49
    • Sun, C.1    Sathish, P.2    Ahlandsberg, S.3    Jansson, C.4
  • 46
    • 0026482438 scopus 로고
    • High density molecular linkage maps of the tomato and potato genomes
    • Tanksley, S.D., Ganal, M.W., Prince, J.P. et al. (1992) High density molecular linkage maps of the tomato and potato genomes. Genetics, 132, 1141-1160.
    • (1992) Genetics , vol.132 , pp. 1141-1160
    • Tanksley, S.D.1    Ganal, M.W.2    Prince, J.P.3
  • 48
    • 0001607723 scopus 로고
    • Distantly related sequences in the α- and β-subunits of ATP synthetase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
    • Walker, J.E., Saraste, M., Runswick, M.J. and Gay, N.J. (1982) Distantly related sequences in the α- and β-subunits of ATP synthetase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1, 945-951.
    • (1982) EMBO J. , vol.1 , pp. 945-951
    • Walker, J.E.1    Saraste, M.2    Runswick, M.J.3    Gay, N.J.4
  • 49
    • 0027931646 scopus 로고
    • The product of the tobacco mosaic virus resistance gene N: Similarity to Toll and the Interleukin-1 receptor
    • Whitham, S., Dinesh-Kumar, S.P., Choi, D., Hehl, R., Corr, C. and Baker, B. (1994) The product of the tobacco mosaic virus resistance gene N: similarity to Toll and the Interleukin-1 receptor. Cell, 78, 1101-1115.
    • (1994) Cell , vol.78 , pp. 1101-1115
    • Whitham, S.1    Dinesh-Kumar, S.P.2    Choi, D.3    Hehl, R.4    Corr, C.5    Baker, B.6
  • 50
    • 0030266290 scopus 로고    scopus 로고
    • Nematode pathogenesis and resistance in plants
    • Williamson, V.M. and Hussey, R.S. (1996) Nematode pathogenesis and resistance in plants. Plant Cell, 8, 1735-1745.
    • (1996) Plant Cell , vol.8 , pp. 1735-1745
    • Williamson, V.M.1    Hussey, R.S.2


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