Inhibition of glucose-induced electrical activity in rat pancreatic β-cells by DCPIB, a selective inhibitor of volume-sensitive anion currents

European Journal of Pharmacology

Volumn 489, Issue 1-2, 2004, Pages 13-19

  Best, Leonard ^a,d   Yates, Allen P ^a   Decher, Neils ^b   Steinmeyer, Klaus ^c   Nilius, Bernd ^c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

DCPIB; Insulin release; Islet; KATP channel; Pancreatic cell; Volume sensitive anion channel

Indexed keywords

4 (2 BUTYL 6,7 DICHLORO 2 CYCLOPENTYLINDAN 1 ON 5 YL)OXOBUTYRIC ACID; ETACRYNIC ACID; GLUCOSE; TOLBUTAMIDE; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CELL MEMBRANE POTENTIAL; CELL METABOLISM; CELL SECRETION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG INHIBITION; ELECTRIC ACTIVITY; ELECTRIC CONDUCTIVITY; GLUCOSE METABOLISM; GLUCOSE OXIDATION; HYPERPOLARIZATION; IC 50; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT;

ANIMALS; CELL MEMBRANE; CYCLOPENTANES; ELECTROPHYSIOLOGY; GLUCOSE; HYPOGLYCEMIC AGENTS; INDANS; INSULIN; ION CHANNEL GATING; ION CHANNELS; ISLETS OF LANGERHANS; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; TOLBUTAMIDE;

EID: 1942420342     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.02.030     Document Type: Article

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