Evidence that glucose-induced electrical activity in rat pancreatic β-cells does not require KATP channel inhibition

Journal of Membrane Biology

Volumn 185, Issue 3, 2002, Pages 193-200

  Best, L ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Electrical activity; Islet; KATP channel; Pancreatic cell; Volume sensitive anion channel

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANION CHANNEL; GLUCOSE; POTASSIUM CHANNEL; POTASSIUM ION; SULFONYLUREA DERIVATIVE; TOLBUTAMIDE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE CONDUCTANCE; ELECTRIC ACTIVITY; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; RAT; VOLTAGE CLAMP;

ADENOSINE TRIPHOSPHATE; ANIMALS; GLUCOSE; ISLETS OF LANGERHANS; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RATS; TETRAETHYLAMMONIUM; TOLBUTAMIDE;

ANIMALIA;

EID: 0036468497     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-001-0114-1     Document Type: Article

References (34)

1. Glucose action 'beyond ionic events' in the pancreatic beta-cell
2. 2+ concentration in pancreatic β-cells
3. Properties of single potassium channels modulated by glucose in rat pancreatic β-cells
4. Electrophysiology of the pancreatic β-cell
5. Glucose and 2-ketoisocaproate induce transient inward currents in rat pancreatic beta cells
6. Cell-attached recordings of the volume-sensitive anion channel in rat pancreatic β-cells
7. Glucose-sensitive conductances in rat pancreatic beta-cells: Contribution to electrical activity
8. Inhibition of glucose-induced electrical activity by 4-hydroxytamoxifen in rat pancreatic β-cells
9. Selective inhibition of glucose-stimulated beta-cell activity by an anion channel inhibitor
10. Activation of an anion conductance and depolarization during hypotonically-induced insulin release
11. A volume-activated anion conductance in insulin-secreting cells
12. Functional characterization of the volume-sensitive anion channel in rat pancreatic β-cells
13. +) permeability
14. + channels that are inhibited by ATP in an insulin-secreting cell line
15. + channel from venom of the scorpion Buthus tamulus
16. + channels in mouse B-cells
17. + channels in mouse B-cells
18. Tolbutamide stimulation and inhibition of insulin release: Studies of the underlying ionic mechanisms in isolated rat islets
19. A minimum of fuel is necessary for tolbutamide to mimic the effects of glucose on electrical activity in pancreatic β-cells
20. Triggering and amplifying pathways of regulation of insulin secretion by glucose
21. An ATP-sensitive C-channel current that is activated by cell swelling, cAMP and glyburide in insulin-secreting cells
22. 2+: New insights into stimulus-secretion coupling
23. Insulin release: The fuel hypothesis
24. 1 changes in single rat pancreatic islets and correlation with simultaneously measured insulin release
25. Regulation of a volume-sensitive anion channel in rat pancreatic β-cells by intracellular adenine nucleotides
26. Glucose-induced swelling in rat pancreatic beta-cells
27. Interaction of stilbene disulphonates with cloned K(ATP) channels
28. Low access resistance perforated patch recordings using amphotericin B
29. The pancreatic beta-cell as a fuel sensor: An electrophysiologist's viewpoint
30. +-channels in pancreatic β- cells are regulated by intracellular ATP
31. + currents in isolated mouse pancreatic β-cells
32. Glucose activates both K(ATP) channel-dependent and K(ATP) channel-independent signalling pathways in human islets
33. The sulfonylurea receptor may be an ATP-sensitive potassium channel
34. Glucose-regulated pulsatile insulin release from mouse islets via the K(ATP) channel-independent pathway