-
1
-
-
0012473279
-
The nuclear receptor superfamily: The second decade
-
D.J. Mangelsdorf, C. Thummel, M. Beato, P. Herrlich, G. Schutz, K. Umesono, B. Blumberg, P. Kastner, M. Mark, P. Chambon, and R.M. Evans The nuclear receptor superfamily: the second decade Cell 83 1995 835 839
-
(1995)
Cell
, vol.83
, pp. 835-839
-
-
Mangelsdorf, D.J.1
Thummel, C.2
Beato, M.3
Herrlich, P.4
Schutz, G.5
Umesono, K.6
Blumberg, B.7
Kastner, P.8
Mark, M.9
Chambon, P.10
Evans, R.M.11
-
2
-
-
0029731662
-
Peroxisome proliferator-activated receptors: A nuclear receptor signaling pathway in lipid physiology
-
T. Lemberger, B. Desvergne, and W. Wahli Peroxisome proliferator- activated receptors: a nuclear receptor signaling pathway in lipid physiology Ann. Rev. Cell. Dev. Biol. 12 1996 335 363
-
(1996)
Ann. Rev. Cell. Dev. Biol.
, vol.12
, pp. 335-363
-
-
Lemberger, T.1
Desvergne, B.2
Wahli, W.3
-
3
-
-
0030297919
-
Adipogenesis and obesity: Rounding out the big picture
-
B.M. Spiegelman, and J.S. Flier Adipogenesis and obesity: rounding out the big picture Cell 84 1996 377 389
-
(1996)
Cell
, vol.84
, pp. 377-389
-
-
Spiegelman, B.M.1
Flier, J.S.2
-
4
-
-
0031671246
-
Differentiation and reversal of malignant changes in colon cancer through PPARγ
-
P. Sarraf, E. Mueller, D. Jones, F. King, D.J. DeAngelo, J.B. Partridge, S.A. Holden, L.B. Chen, S. Singer, C. Fletcher, and B.M. Spiegelman Differentiation and reversal of malignant changes in colon cancer through PPARγ Nat. Med. 4 1998 1046 1052
-
(1998)
Nat. Med.
, vol.4
, pp. 1046-1052
-
-
Sarraf, P.1
Mueller, E.2
Jones, D.3
King, F.4
Deangelo, D.J.5
Partridge, J.B.6
Holden, S.A.7
Chen, L.B.8
Singer, S.9
Fletcher, C.10
Spiegelman, B.M.11
-
5
-
-
0031595670
-
Activation of PPARγ leads to inhibition of anchorage-independent growth of human colorectal cancer cells
-
J.A. Brockman, R.A. Gupta, and R.N. DuBois Activation of PPARγ leads to inhibition of anchorage-independent growth of human colorectal cancer cells Gastroenterology 115 1998 1049 1055
-
(1998)
Gastroenterology
, vol.115
, pp. 1049-1055
-
-
Brockman, J.A.1
Gupta, R.A.2
Dubois, R.N.3
-
6
-
-
0033006938
-
Peroxisome proliferator-activated receptor γ induces growth arrest and differentiation markers of human colon cancer cells
-
S. Kitamura, Y. Miyazaki, Y. Shinomura, S. Kondo, S. Kanayama, and Y. Matsuzawa Peroxisome proliferator-activated receptor γ induces growth arrest and differentiation markers of human colon cancer cells Jpn. J. Cancer Res. 90 1999 75 80
-
(1999)
Jpn. J. Cancer Res.
, vol.90
, pp. 75-80
-
-
Kitamura, S.1
Miyazaki, Y.2
Shinomura, Y.3
Kondo, S.4
Kanayama, S.5
Matsuzawa, Y.6
-
7
-
-
12644265334
-
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptorγ and the retinoid X receptor
-
P. Tontonoz, S. Singer, B.M. Forman, P. Sarraf, J.A. Fletcher, C.D. Fletcher, R.P. Burn, E. Mueller, S. Altiok, H. Oppenheim, R.M. Evans, and B.M. Spiegelman Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptorγ and the retinoid X receptor Proc. Natl. Acad. Sci. USA 94 1997 237 241
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 237-241
-
-
Tontonoz, P.1
Singer, S.2
Forman, B.M.3
Sarraf, P.4
Fletcher, J.A.5
Fletcher, C.D.6
Burn, R.P.7
Mueller, E.8
Altiok, S.9
Oppenheim, H.10
Evans, R.M.11
Spiegelman, B.M.12
-
8
-
-
0032145363
-
Ligand for peroxisome proliferator-activated receptor γ (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo
-
T. Kubota, K. Koshizuka, E.A. Williamson, H. Asou, J.W. Said, S. Holden, I. Miyoshi, and H.P. Koeffler Ligand for peroxisome proliferator-activated receptor γ (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo Cancer Res. 58 1998 3344 3352
-
(1998)
Cancer Res.
, vol.58
, pp. 3344-3352
-
-
Kubota, T.1
Koshizuka, K.2
Williamson, E.A.3
Asou, H.4
Said, J.W.5
Holden, S.6
Miyoshi, I.7
Koeffler, H.P.8
-
9
-
-
0032555196
-
Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
-
E. Elstner, C. Muller, K. Koshizuka, E.A. Williamson, D. Park, H. Asou, P. Shintaku, J.W. Said, D. Heber, and H.P. Koeffler Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice Proc. Natl. Acad. Sci. USA 95 1998 8806 8811
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8806-8811
-
-
Elstner, E.1
Muller, C.2
Koshizuka, K.3
Williamson, E.A.4
Park, D.5
Asou, H.6
Shintaku, P.7
Said, J.W.8
Heber, D.9
Koeffler, H.P.10
-
10
-
-
0031993322
-
Terminal differentiation of human breast cancer through PPARγ
-
E. Mueller, P. Sarraf, P. Tontonoz, R.M. Evans, K.J. Martin, M. Zhang, C. Fletcher, S. Singer, and B.M. Spiegelman Terminal differentiation of human breast cancer through PPARγ Mol. Cell 1 1998 465 470
-
(1998)
Mol. Cell
, vol.1
, pp. 465-470
-
-
Mueller, E.1
Sarraf, P.2
Tontonoz, P.3
Evans, R.M.4
Martin, K.J.5
Zhang, M.6
Fletcher, C.7
Singer, S.8
Spiegelman, B.M.9
-
11
-
-
0032586875
-
Activation of PPARγ inhibits cell growth and induces apoptosis in human gastric cancer cells
-
N. Takahashi, T. Okumura, W. Motomura, Y. Fujimoto, I. Kawabata, and Y. Kohgo Activation of PPARγ inhibits cell growth and induces apoptosis in human gastric cancer cells FEBS Lett. 455 1999 135 139
-
(1999)
FEBS Lett.
, vol.455
, pp. 135-139
-
-
Takahashi, N.1
Okumura, T.2
Motomura, W.3
Fujimoto, Y.4
Kawabata, I.5
Kohgo, Y.6
-
12
-
-
0034652462
-
Induction of differentiation and apoptosis by ligands of peroxisome proliferator activated receptor gamma in non-small cell lung cancer
-
T.H. Chang, and E. Szabo Induction of differentiation and apoptosis by ligands of peroxisome proliferator activated receptor gamma in non-small cell lung cancer Cancer Res. 60 2000 1129 1138
-
(2000)
Cancer Res.
, vol.60
, pp. 1129-1138
-
-
Chang, T.H.1
Szabo, E.2
-
14
-
-
0033546710
-
WAF/CIP1 cyclin-dependent kinase inhibitor
-
WAF/CIP1 cyclin-dependent kinase inhibitor Biochem. Biophys. Res. Commun. 261 1999 833 837
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.261
, pp. 833-837
-
-
Sugimura, A.1
Kiriyama, Y.2
Nochi, H.3
Tsuchiya, H.4
Tamoto, K.5
Sakurada, Y.6
Ui, M.7
Tokumitsu, Y.8
-
16
-
-
0028176483
-
Kip1, a cyclin-Cdk inhibitor and potential mediator of extracellular antimitogenic signals
-
Kip1, a cyclin-Cdk inhibitor and potential mediator of extracellular antimitogenic signals Cell 78 1994 59 66
-
(1994)
Cell
, vol.78
, pp. 59-66
-
-
Polyak, K.1
Lee, M.H.2
Erdjument-Bromage, M.3
Koff, A.4
Roberts, J.M.5
Tempst, P.6
Massague, J.7
-
17
-
-
0028363519
-
P27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
-
H. Toyoshima, and T. Hunter p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21 Cell 78 1994 67 74
-
(1994)
Cell
, vol.78
, pp. 67-74
-
-
Toyoshima, H.1
Hunter, T.2
-
18
-
-
0037513312
-
PPARγ ligand-induced apoptosis through a p53 dependent mechanism in human gastric cancer cell
-
M. Nagamine, T. Okumura, S. Tanno, M. Sawamukai, W. Motomura, N. Takahashi, and Y. Kohgo PPARγ ligand-induced apoptosis through a p53 dependent mechanism in human gastric cancer cell Cancer Sci. 94 2003 338 343
-
(2003)
Cancer Sci.
, vol.94
, pp. 338-343
-
-
Nagamine, M.1
Okumura, T.2
Tanno, S.3
Sawamukai, M.4
Motomura, W.5
Takahashi, N.6
Kohgo, Y.7
-
19
-
-
0031900740
-
Signal transduction through MAP kinase cascades
-
T.S. Lewis, P.S. Shapiro, and N.G. Ahn Signal transduction through MAP kinase cascades Adv. Cancer Res. 74 1998 49 139
-
(1998)
Adv. Cancer Res.
, vol.74
, pp. 49-139
-
-
Lewis, T.S.1
Shapiro, P.S.2
Ahn, N.G.3
-
20
-
-
0031754323
-
Cyclic-GMP-dependent protein kinase inhibits the Ras/mitogen-activated protein kinase pathway
-
M. Suhasini, H. Li, S.M. Lohmann, G.R. Boss, and R.B. Pilz Cyclic-GMP-dependent protein kinase inhibits the Ras/mitogen-activated protein kinase pathway Mol. Cell Biol. 18 1998 6983 6994
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 6983-6994
-
-
Suhasini, M.1
Li, H.2
Lohmann, S.M.3
Boss, G.R.4
Pilz, R.B.5
-
21
-
-
0032984348
-
Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
-
J.S. Sebolt-Leopold, D.T. Dudley, R. Herrera, K.V. Becelaere, A. Wiland, R.C. Gowan, H. Tecle, S.D. Barrett, A. Bridges, S. Przybranowski, W. Leopold, and A.R. Saltiel Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo Nat. Med. 5 1999 810 816
-
(1999)
Nat. Med.
, vol.5
, pp. 810-816
-
-
Sebolt-Leopold, J.S.1
Dudley, D.T.2
Herrera, R.3
Becelaere, K.V.4
Wiland, A.5
Gowan, R.C.6
Tecle, H.7
Barrett, S.D.8
Bridges, A.9
Przybranowski, S.10
Leopold, W.11
Saltiel, A.R.12
-
22
-
-
0033081066
-
Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry
-
A. Brunet, R.D. Roux, P. Lenormand, S. Dowd, S. Keyse, and J. Pouyssegur Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry EMBO J. 18 1999 664 674
-
(1999)
EMBO J.
, vol.18
, pp. 664-674
-
-
Brunet, A.1
Roux, R.D.2
Lenormand, P.3
Dowd, S.4
Keyse, S.5
Pouyssegur, J.6
-
23
-
-
0029786329
-
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38 MAPK pathway
-
J.N. Lavoie, G. L'Allemain, A. Brunet, R. Muller, and J. Pouyssegu Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38 MAPK pathway J. Biol. Chem. 271 1996 20608 20616
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20608-20616
-
-
Lavoie, J.N.1
L'Allemain, G.2
Brunet, A.3
Muller, R.4
Pouyssegu, J.5
-
24
-
-
0021237975
-
Establishment of a human pancreatic cancer cell line and detection of pancreatic associated antigen
-
M. Kobori, S. Matsuno, T. Sato, M. Kan, and T. Tachibana Establishment of a human pancreatic cancer cell line and detection of pancreatic associated antigen Tohoku J. Exp. Med. 143 1984 33 46
-
(1984)
Tohoku J. Exp. Med.
, vol.143
, pp. 33-46
-
-
Kobori, M.1
Matsuno, S.2
Sato, T.3
Kan, M.4
Tachibana, T.5
-
25
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma
-
J.M. Lehmann, L.B. Moore, T.A. Smith-Oliver, W.O. Wilkison, T.M. Willson, and S.A. Kliewer An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma J. Biol. Chem. 270 1995 12953 12956
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
26
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
M.F. Favata, K.Y. Horiuchi, E.J. Manos, A.J. Daulerio, D.A. Stradley, W.S. Feeser, D.E. Van Dyk, W.J. Pitts, R.A. Earl, F. Hobbs, R.A. Copeland, R.L. Magolda, P.A. Scherle, and K.M. Trzaskos Identification of a novel inhibitor of mitogen-activated protein kinase kinase J. Biol. Chem. 273 1998 18623 18632
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
Daulerio, A.J.4
Stradley, D.A.5
Feeser, W.S.6
Van Dyk, D.E.7
Pitts, W.J.8
Earl, R.A.9
Hobbs, F.10
Copeland, R.A.11
Magolda, R.L.12
Scherle, P.A.13
Trzaskos, K.M.14
-
27
-
-
0029166667
-
A synthetic inhibitor of the mitogen-activated protein kinase cascade
-
D.T. Dudley, L. Pang, S.J. Decker, A.J. Bridges, and A.R. Saltiel A synthetic inhibitor of the mitogen-activated protein kinase cascade Proc. Natl. Acad. Sci. USA 92 1995 7686 7689
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7686-7689
-
-
Dudley, D.T.1
Pang, L.2
Decker, S.J.3
Bridges, A.J.4
Saltiel, A.R.5
-
28
-
-
0036053466
-
Troglitazone induces G1 arrest by p27Kip1 induction that is mediated by inhibition of proteasome in human gastric cancer cells
-
S. Takeuchi, T. Okumura, W. Motomura, M. Nagamine, N. Takahashi, and Y. Kohgo Troglitazone induces G1 arrest by p27Kip1 induction that is mediated by inhibition of proteasome in human gastric cancer cells Jpn. J. Cancer Res. 93 2002 774 782
-
(2002)
Jpn. J. Cancer Res.
, vol.93
, pp. 774-782
-
-
Takeuchi, S.1
Okumura, T.2
Motomura, W.3
Nagamine, M.4
Takahashi, N.5
Kohgo, Y.6
-
29
-
-
0030773524
-
Regulation of gastric epithelial cell growth by Helicobacter pylori: Evidence for a major role of apoptosis
-
S. Wagner, W. Bell, J. Westermann, R.P. Logan, C.T. Bock, C. Trautwein, J.S. Bleck, and M.P. Manns Regulation of gastric epithelial cell growth by Helicobacter pylori: evidence for a major role of apoptosis Gastroenterology 113 1997 1836 1847
-
(1997)
Gastroenterology
, vol.113
, pp. 1836-1847
-
-
Wagner, S.1
Bell, W.2
Westermann, J.3
Logan, R.P.4
Bock, C.T.5
Trautwein, C.6
Bleck, J.S.7
Manns, M.P.8
-
30
-
-
3042569217
-
Inhibition of cell invasion and morphological change by troglitazone in cultured human pancreatic cancer cells
-
W. Motomura, M. Nagamine, S. Tanno, M. Sawamukai, N. Takahashi, Y. Kohgo, and T. Okumura Inhibition of cell invasion and morphological change by troglitazone in cultured human pancreatic cancer cells J. Gastroenterol. 39 2004 461 468
-
(2004)
J. Gastroenterol.
, vol.39
, pp. 461-468
-
-
Motomura, W.1
Nagamine, M.2
Tanno, S.3
Sawamukai, M.4
Takahashi, N.5
Kohgo, Y.6
Okumura, T.7
-
31
-
-
0032984348
-
Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
-
J.S. Sebolt-Leopold, D.T. Dudley, R. Herrera, K. Van Becelaere, A. Wiland, R.C. Gowan, H. Tecle, S.D. Barrett, A. Bridges, S. Przybranowski, W.R. Leopold, and A.R. Saltiel Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo Nat. Med. 7 1999 810 816
-
(1999)
Nat. Med.
, vol.7
, pp. 810-816
-
-
Sebolt-Leopold, J.S.1
Dudley, D.T.2
Herrera, R.3
Van Becelaere, K.4
Wiland, A.5
Gowan, R.C.6
Tecle, H.7
Barrett, S.D.8
Bridges, A.9
Przybranowski, S.10
Leopold, W.R.11
Saltiel, A.R.12
-
32
-
-
0035866338
-
Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites
-
P.L. Rice, R.J. Goldberg, E.C. Ray, L.J. Driggers, and D.J. Ahnen Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites Cancer Res. 61 2001 1541 1547
-
(2001)
Cancer Res.
, vol.61
, pp. 1541-1547
-
-
Rice, P.L.1
Goldberg, R.J.2
Ray, E.C.3
Driggers, L.J.4
Ahnen, D.J.5
-
33
-
-
0242349249
-
MEK inhibition of pancreatic carcinoma cells by U0126 and its effect in combination with sulindac
-
M.T. Yip-Schneider, and C.M. Schmidt MEK inhibition of pancreatic carcinoma cells by U0126 and its effect in combination with sulindac Pancreas 27 2003 337 344
-
(2003)
Pancreas
, vol.27
, pp. 337-344
-
-
Yip-Schneider, M.T.1
Schmidt, C.M.2
-
34
-
-
0034618369
-
MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells
-
M.J. Boucher, J. Morisset, P.H. Vachon, J.C. Reed, J. Laine, and N. Rivard MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells J. Cell. Biochem. 79 2000 355 369
-
(2000)
J. Cell. Biochem.
, vol.79
, pp. 355-369
-
-
Boucher, M.J.1
Morisset, J.2
Vachon, P.H.3
Reed, J.C.4
Laine, J.5
Rivard, N.6
-
35
-
-
19644397029
-
Adhesion control of cyclin D1 and p27(Kip1) levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling
-
K.V. Bhatt, L.S. Spofford, G. Aram, M. McMullen, K. Pumiglia, and A.E. Aplin Adhesion control of cyclin D1 and p27(Kip1) levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling Oncogene 23 2005 1 13
-
(2005)
Oncogene
, vol.23
, pp. 1-13
-
-
Bhatt, K.V.1
Spofford, L.S.2
Aram, G.3
McMullen, M.4
Pumiglia, K.5
Aplin, A.E.6
|