Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library

PLoS Biology

Volumn 2, Issue 4, 2004, Pages

  Crawford, Frances ^a,b   Huseby, Eric ^a,b   White, Janice ^a   Marrack, Philippa ^a,b   Kappler, John W ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN; PEPTIDE; PEPTIDE LIBRARY; T LYMPHOCYTE ANTIGEN; T LYMPHOCYTE RECEPTOR; VIRUS DNA; B7 ANTIGEN; HLA ANTIGEN CLASS 1; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY; OLIGONUCLEOTIDE;

ALLOIMMUNITY; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN ANTIBODY COMPLEX; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CONTROLLED STUDY; FLUORESCENCE; INSECT CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; METHODOLOGY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FAMILY; PROTEIN INTERACTION; SOLUBILITY; T LYMPHOCYTE; VIRUS INFECTION; ANIMAL; BACULOVIRUS; C57BL MOUSE; CELL LINE; CHEMISTRY; DNA SEQUENCE; FLOW CYTOMETRY; GENE LIBRARY; GENETICS; HYBRIDOMA; IMMUNOLOGY; INSECT; METABOLISM; MOLECULAR GENETICS; SEQUENCE HOMOLOGY;

ANIMALIA; DNA VIRUSES; INSECTA; UNIDENTIFIED BACULOVIRUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD80; BACULOVIRIDAE; CELL LINE; DNA, VIRAL; EPITOPES; EPITOPES, T-LYMPHOCYTE; FLOW CYTOMETRY; GENE LIBRARY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HYBRIDOMAS; INSECTS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-2; LIGANDS; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; PEPTIDE LIBRARY; PEPTIDES; RECEPTORS, ANTIGEN, T-CELL; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; T-LYMPHOCYTES;

EID: 19344375899     PISSN: 15449173     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pbio.0020090     Document Type: Article

References (48)

1. Boder ET, Wittrup KD (2000) Yeast surface display for directed evolution of protein expression, affinity, and stability. Methods Enzymol 328: 430-444. Find this article online
2. Brock R, Wiesmuller KH, Jung G, Walden P (1996) Molecular basis for the recognition of two structurally different major histocompatibility complex/peptide complexes by a single T-cell receptor. Proc Natl Acad Sci U S A 93: 13108-13113. Find this article online
3. Brophy SE, Holler PD, Kranz DM (2003) A yeast display system for engineering functional peptide-MHC complexes. J Immunol Methods 272: 235-246. Find this article online
4. + T cells. Proc Natl Acad Sci U S A 93: 14736-14741. Find this article online
5. Crawford F, Kozono H, White J, Marrack P, Kappler J (1998) Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity 8: 675-682. Find this article online
6. Dongre AR, Kovats S, deRoos P, McCormack AL, Nakagawa T, et al. (2001) In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses. Eur J Immunol 31: 1485-1494. Find this article online
7. Ernst WJ, Grabherr RM, Katinger HW (1994) Direct cloning into the Autographa californica nuclear polyhedrosis virus for generation of recombinant baculoviruses. Nucleic Acids Res 22: 2855-2856. Find this article online
8. Ernst W, Grabherr R, Wegner D, Borth N, Grassauer A, et al. (1998) Baculovirus surface display: Construction and screening of a eukaryotic epitope library. Nucleic Acids Res 26: 1718-1723. Find this article online
9. Evavold BD, Allen PM (1992) Dissection of the Hb(64-76) determinant reveals that the T cell receptor may have the capacity to differentially signal. Adv Exp Med Biol 323: 17-21. Find this article online
10. Evavold BD, Sloan-Lancaster J, Allen PM (1993) Tickling the TCR: Selective T-cell functions stimulated by altered peptide ligands. Immunol Today 14: 602-609. Find this article online
11. Garcia KC, Teyton L, Wilson IA (1999) Structural basis of T cell recognition. Annu Rev Immunol 17: 369-397. Find this article online
12. Gavin MA, Dere B, Grandea AG, Hogquist KA, Bevan MJ (1994) Major histocompatibility complex class I allele-specific peptide libraries: Identification of peptides that mimic an H-Y T cell epitope. Eur J Immunol 24: 2124-2133. Find this article online
13. Guimezanes A, Barrett-Wilt GA, Gulden-Thompson P, Shabanowitz J, Engelhard VH, et al. (2001) Identification of endogenous peptides recognized by in vivo or in vitro generated alloreactive cytotoxic T lymphocytes: Distinct characteristics correlated with CD8 dependence. Eur J Immunol 31: 421-432. Find this article online
14. Hiemstra HS, Drijfhout JW, Roep BO (2000) Antigen arrays in T cell immunology. Curr Opin Immunol 12: 80-84. Find this article online
15. Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, et al. (1994) T cell receptor antagonist peptides induce positive selection. Cell 76: 17-27. Find this article online
16. Huseby ES, Crawford F, White J, Kappler J, Marrack P (2003) Negative selection imparts peptide specificity to the mature T cell repertoire. Proc Natl Acad Sci U S A 100: 11565-11570. Find this article online
17. Ignatowicz L, Kappler J, Marrack P (1996) The repertoire of T cells shaped by a single MHC/peptide ligand. Cell 84: 521-529. Find this article online
18. + B cell hybridomas to H-2-restricted T cell hybridomas. Proc Natl Acad Sci U S A 79: 3604-3607. Find this article online
19. Kappler J, White J, Kozono H, Clements J, Marrack P (1994) Binding of a soluble alpha beta T-cell receptor to superantigen/major histocompatibility complex ligands. Proc Natl Acad Sci U S A 91: 8462-8466. Find this article online
20. Kitts PA, Possee RD (1993) A method for producing recombinant baculovirus expression vectors at high frequency. Biotechniques 14: 810-817. Find this article online
21. Kozono H, White J, Clements J, Marrack P, Kappler J (1994) Production of soluble MHC class II proteins with covalently bound single peptides. Nature 369: 151-154. Find this article online
22. Lemke H, Hammerling GJ, Hammerling U (1979) Fine specificity analysis with monoclonal antibodies of antigens controlled by the major histocompatibility complex and by the Qa/TL region in mice. Immunol Rev 47: 175-206. Find this article online
23. Linnemann T, Tumenjargal S, Gellrich S, Wiesmuller K, Kaltoft K, et al. (2001) Mimotopes for tumor-specific T lymphocytes in human cancer determined with combinatorial peptide libraries. Eur J Immunol 31: 156-165. Find this article online
24. Liu CP, Crawford F, Marrack P, Kappler J (1998) T cell positive selection by a high density, low affinity ligand. Proc Natl Acad Sci U S A 95: 4522-4526. Find this article online
25. Liu R, Enstrom AM, Lam KS (2003) Combinatorial peptide library methods for immunobiology research. Exp Hematol 31: 11-30. Find this article online
26. Liu X, Dai S, Crawford F, Fruge R, Marrack P, et al. (2002) Alternate interactions define the binding of peptides to the MHC molecule IA(b). Proc Natl Acad Sci U S A 99: 8820-8825. Find this article online
27. Lyons DS, Lieberman SA, Hampl J, Boniface JJ, Chien Y, et al. (1996) A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists. Immunity 5: 53-61. Find this article online
28. Marrack P, Bender J, Jordan M, Rees W, Robertson J, et al. (2001) Major histocompatibility complex proteins and TCRs: Do they really go together like a horse and carriage? J Immunol 167: 617-621. Find this article online
29. Mitchell TC, Hildeman D, Kedl RM, Teague TK, Schaefer BC, et al. (2001) Immunological adjuvants promote activated T cell survival via induction of Bcl-3. Nat Immunol 2: 397-402. Find this article online
30. Mottez E, Langlade-Demoyen P, Gournier H, Martinon F, Maryanski J, et al. (1995) Cells expressing a major histocompatibility complex class I molecule with a single covalently bound peptide are highly immunogenic. J Exp Med 181: 493-502. Find this article online
31. O'Shea EK, Lumb KJ, Kim PS (1993) Peptide 'Velcro:" Design of a heterodimeric coiled coil. Curr Biol 3: 658-667. Find this article online
32. Partidos CD (2000) Peptide mimotopes as candidate vaccines. Curr Opin Mol Ther 2: 74-79.
33. Peakman TC, Harris RA, Gewert DR (1992) Highly efficient generation of recombinant baculoviruses by enzymatically medicated site-specific in vitro recombination. Nucleic Acids Res 20: 495-500. Find this article online
34. Reay PA, Kantor RM, Davis MM (1994) Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93-103). J Immunol 152: 3946-3957. Find this article online
35. Rees W, Bender J, Teague TK, Kedl RM, Crawford F, et al. (1999) An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro. Proc Natl Acad Sci U S A 96: 9781-9786. Find this article online
36. Sahara H, Shastri N (2003) Second class minors: molecular identification of the autosomal H46 histocompatibility locus as a peptide presented by major histocompatibility complex class II molecules. J Exp Med 197: 375-385. Find this article online
37. Schaefer BC, Mitchell TC, Kappler JW, Marrack P (2001) A novel family of retroviral vectors for the rapid production of complex stable cell lines. Anal Biochem 297: 86-93. Find this article online
38. Schatz PJ (1993) Use of peptide libraries to map the substrate specificity of a peptide-modifying enzyme: A 13 residue consensus peptide specifies biotinylation in Escherichia coli. Biotechnology (N Y) 11: 1138-1143. Find this article online
39. Scott D, Addey C, Ellis P, James E, Mitchell MJ, et al. (2000) Dendritic cells permit identification of genes encoding MHC class II-restricted epitopes of transplantation antigens. Immunity 12: 711-720. Find this article online
40. Shastri N, Schwab S, Serwold T (2002) Producing nature's gene-chips: The generation of peptides for display by MHC class I molecules. Annu Rev Immunol 20: 463-493. Find this article online
41. Shusta EV, Holler PD, Kieke MC, Kranz DM, Wittrup KD (2000) Directed evolution of a stable scaffold for T-cell receptor engineering. Nat Biotechnol 18: 754-759. Find this article online
42. Simpson E, Scott D, James E, Lombardi G, Cwynarski K, et al. (2001) Minor H antigens: Genes and peptides. Eur J Immunogenet 28: 505-513. Find this article online
43. Sung MH, Zhao Y, Martin R, Simon R (2002) T-cell epitope prediction with combinatorial peptide libraries. J Comput Biol 9: 527-539. Find this article online
44. Uger RA, Barber BH (1998) Creating CTL targets with epitope-linked beta 2-microglobulin constructs. J Immunol 160: 1598-1605. Find this article online
45. Van Der Bruggen P, Zhang Y, Chaux P, Stroobant V, Panichelli C, et al. (2002) Tumor-specific shared antigenic peptides recognized by human T cells. Immunol Rev 188: 51-64. Find this article online
46. White J, Crawford F, Fremont D, Marrack P, Kappler J (1999) Soluble class I MHC with beta2-microglobulin covalently linked peptides: specific binding to a T cell hybridoma. J Immunol 162: 2671-2676. Find this article online
47. White J, Kappler J, Marrack P (2000) Production and characterization of T cell hybridomas. Methods Mol Biol 134: 185-193. Find this article online
48. You S, Chen C, Lee WH, Wu CH, Judkowski V, et al. (2003) Detection and characterization of T cells specific for BDC2.5 T cell-stimulating peptides. J Immunol 170: 4011-4020. Find this article online