-
1
-
-
0038670241
-
Mutational analysis of the tyrosine kinome in colorectal cancers
-
Bardelli, A. et al. Mutational analysis of the tyrosine kinome in colorectal cancers. Science 300, 949 (2003).
-
(2003)
Science
, vol.300
, pp. 949
-
-
Bardelli, A.1
-
2
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch, T. J. et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. New Engl. J. Med. 350, 2129-2132 (2004).
-
(2004)
New Engl. J. Med.
, vol.350
, pp. 2129-2132
-
-
Lynch, T.J.1
-
3
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez, J. G. et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304, 1497-1500 (2004).
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
-
4
-
-
2942594183
-
Targeting non-small cell lung cancer with epidermal growth factor tyrosine kinase inhibitors: Where do we stand, where do we go
-
Patel, J. D., Pasche, B. & Argiris, A. Targeting non-small cell lung cancer with epidermal growth factor tyrosine kinase inhibitors: where do we stand, where do we go. Critical Rev. Oncol. Hematol. 50, 175-186 (2004).
-
(2004)
Critical Rev. Oncol. Hematol.
, vol.50
, pp. 175-186
-
-
Patel, J.D.1
Pasche, B.2
Argiris, A.3
-
5
-
-
4344645978
-
Can the pharmaceutical industry reduce attrition rates?
-
Kola, I. & Landis, J. Can the pharmaceutical industry reduce attrition rates? Nature Rev. Drug Discov. 3, 711-715 (2004).
-
(2004)
Nature Rev. Drug Discov.
, vol.3
, pp. 711-715
-
-
Kola, I.1
Landis, J.2
-
7
-
-
18944367776
-
Pharmaceutical giants fund start-ups
-
Tolchin, E. Pharmaceutical giants fund start-ups. Drug Discov. Devel. 2, 22 (2004).
-
(2004)
Drug Discov Devel.
, vol.2
, pp. 22
-
-
Tolchin, E.1
-
8
-
-
18944367042
-
-
Association of University Technology Managers, Inc. (Lori Pressman, ed.) AUTM Licensing Survey. A Survey Summary of Technology Licensing (and Related) Performance for U. S. and Canadian Academic and Nonprofit Institutions, and Patent Management Firms. Northbrook, IL, USA
-
Association of University Technology Managers, Inc. (Lori Pressman, ed.) AUTM Licensing Survey. A Survey Summary of Technology Licensing (and Related) Performance for U. S. and Canadian Academic and Nonprofit Institutions, and Patent Management Firms. Northbrook, IL, USA, 2003.
-
(2003)
-
-
-
9
-
-
0038699644
-
Value creation and sharing among universities, biotechnology and pharma
-
Edwards, M., Murray, F. & Yu, R. Value creation and sharing among universities, biotechnology and pharma. Nature Biotechnol. 21, 618-624 (2003).
-
(2003)
Nature Biotechnol.
, vol.21
, pp. 618-624
-
-
Edwards, M.1
Murray, F.2
Yu, R.3
-
10
-
-
12144282937
-
NIH response to the conference report request for a plan to ensure taxpayers' interests are protected
-
Department of Health and Human Services. [online]
-
Department of Health and Human Services. NIH response to the conference report request for a plan to ensure taxpayers' interests are protected [online], http://www.nih.gov/news/070101wyden.htm (2001).
-
(2001)
-
-
-
11
-
-
0347986656
-
The emerging role of academia in commercializing innovation
-
Shreefal, M. The emerging role of academia in commercializing innovation. Nature Biotechnol. 22, 21-24 (2004).
-
(2004)
Nature Biotechnol.
, vol.22
, pp. 21-24
-
-
Shreefal, M.1
-
12
-
-
18944388106
-
The NIH Almanac
-
[online]
-
The NIH Almanac [online], http://www.nih.gov/about/almanac/index.html (2003).
-
(2003)
-
-
-
13
-
-
2342644800
-
Why we're losing the war on cancer - And how to win it
-
(22 March )
-
Leaf, C. Why we're losing the war on cancer - and how to win it. Fortune 76f (22 March 2004).
-
(2004)
Fortune
-
-
Leaf, C.1
-
15
-
-
0242385444
-
US NHGRI launches chemical attack on drug development gap
-
Garber, K. US NHGRI launches chemical attack on drug development gap. Nature Biotechnol. 21, 1253-1254 (2003).
-
(2003)
Nature Biotechnol.
, vol.21
, pp. 1253-1254
-
-
Garber, K.1
-
16
-
-
8444225024
-
NIH Molecular Libraries Initiative
-
Austin, C. P., Brady, L. S., Insel, T. R. & Collins, F. S. NIH Molecular Libraries Initiative. Science 306, 1138-1139 (2004).
-
(2004)
Science
, vol.306
, pp. 1138-1139
-
-
Austin, C.P.1
Brady, L.S.2
Insel, T.R.3
Collins, F.S.4
-
17
-
-
0037374498
-
The price of innovation: New estimates of drug development costs
-
DiMasi, J. A., Hansen, R. W. & Grabowski, H. G. The price of innovation: new estimates of drug development costs. J. Health Econ. 22, 151-185 (2003).
-
(2003)
J. Health Econ.
, vol.22
, pp. 151-185
-
-
DiMasi, J.A.1
Hansen, R.W.2
Grabowski, H.G.3
-
18
-
-
0347470986
-
UCSD getting more involved in drug trials
-
SignOnSanDiego.com [online], (31 July )
-
Pollack, A. UCSD getting more involved in drug trials. SignOnSanDiego.com [online], http://www.signonsandiego.com/news/business/biotech/ 20030731-9999_1b31biotech.html (31 July 2003).
-
(2003)
-
-
Pollack, A.1
-
19
-
-
18944396847
-
Novartis opens drug research center in MIT's Tech Square
-
MIT Press Release. [online], (6 May )
-
MIT Press Release. Novartis opens drug research center in MIT's Tech Square [online], http://web.mit.edu/newsoffice/2002/novartis.html (6 May 2002).
-
(2002)
-
-
-
20
-
-
0037118314
-
Boston: A magnetic hub
-
Smaglik, P. Boston: a magnetic hub. Naturejobs 417, 4-5 (2002).
-
(2002)
Naturejobs
, vol.417
, pp. 4-5
-
-
Smaglik, P.1
-
21
-
-
0037902478
-
Building the translational highway: Toward new partnerships between academia and the private sector
-
Schwarz, K. & Iquin, J. T. Building the translational highway: toward new partnerships between academia and the private sector. Nature Med. 9, 493-495 (2003).
-
(2003)
Nature Med.
, vol.9
, pp. 493-495
-
-
Schwarz, K.1
Iquin, J.T.2
-
23
-
-
18944402994
-
A new culture of drug discovery
-
(Fall )
-
Zavoico, G. B. A new culture of drug discovery. NIBR Science (Fall 2004).
-
(2004)
NIBR Science
-
-
Zavoico, G.B.1
-
24
-
-
18944396333
-
Cancer superdrugs, costly side effects
-
(21 June )
-
Arnst, C. Cancer superdrugs, costly side effects. BusinessWeek 44-46 (21 June 2004).
-
(2004)
Business Week
, pp. 44-46
-
-
Arnst, C.1
-
25
-
-
0035976571
-
Research on resistance to cancer drug Gleevec
-
Sawyers, C. L. Research on resistance to cancer drug Gleevec. Science 294, 1834 (2001).
-
(2001)
Science
, vol.294
, pp. 1834
-
-
Sawyers, C.L.1
-
26
-
-
0042067890
-
Oncology's trials
-
Booth, B., Glassman, R. & Ma, P. Oncology's trials. Nature Rev. Drug Discov. 2, 609-610 (2003).
-
(2003)
Nature Rev. Drug Discov.
, vol.2
, pp. 609-610
-
-
Booth, B.1
Glassman, R.2
Ma, P.3
-
27
-
-
18944376877
-
Beyond the blockbuster drug. Strategies for nichebuster drugs, targeted therapies and personalized medicine
-
(February )
-
Beyond the blockbuster drug. Strategies for nichebuster drugs, targeted therapies and personalized medicine. Business Insights (February 2005).
-
(2005)
Business Insights
-
-
-
28
-
-
14044261316
-
What's wrong with our cancer models?
-
Kamb, A. What's wrong with our cancer models? Nature Rev. Drug Discov. 4, 161-165 (2005).
-
(2005)
Nature Rev. Drug Discov.
, vol.4
, pp. 161-165
-
-
Kamb, A.1
-
29
-
-
18944377672
-
-
CMR International 2003 R&D Compendium, Epsom, UK, 32 (March )
-
CMR International 2003 R&D Compendium, Epsom, UK, 32 (March 2003).
-
(2003)
-
-
|