Bone morphogenetic proteins and cholinergic neurons in the central nervous system;Proteínas morfogenéticas óseas y neuronas colinérgicas en el sistema nervioso central

Revista de Neurologia

Volumn 33, Issue 11, 2001, Pages 1054-1060

  López Coviella, Ignacio ^a   Blusztajn, J K ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetylcholine; Alzheimer disease; Bone morphogenetic proteins; Cholinergic neurons; Neurotransmitter phenotype

Indexed keywords

BONE MORPHOGENETIC PROTEIN; NEUROTRANSMITTER;

CELL FUNCTION; CELL SPECIFICITY; CENTRAL NERVOUS SYSTEM; CHOLINERGIC NERVE CELL; HUMAN; NERVE CELL DEGENERATION; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; PHENOTYPE; RECEPTOR UPREGULATION; REVIEW;

EID: 18844464016     PISSN: 02100010     EISSN: None     Source Type: Journal    
DOI: 10.33588/rn.3311.2001445     Document Type: Review

References (91)

1. TGF-β signal transduction
2. Bone morphogenetic proteins in the nervous system
3. The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms
4. The cystine-knot growth-factor superfamily
5. Three-dimensional structure of recombinant human osteogenic protein. I. Structural paradigm for the transforming growth factor β superfamily
6. Expression cloning of an activin receptor, a predicted transmembrane
7. Human type II receptor for bone morphogenic proteins (BMPs): Extension
8. Cloning and characterization of a human type II receptor for bone
9. Identification of a human type II receptor for bone morphogenetic
10. Identification of type I receptors for osteogenic protein-1 and bone
11. Osteogenic protein-1 binds to activin type II receptors and induces
12. Potent ectopic bone-inducing activity of bone morphogenetic protein-4/7
13. Mechanism of activation of the TGF-beta receptor
14. Activation of signaling by the activin receptor complex
15. Biochemical evidence for the autophosphorylation and
16. Formation and activation by phosphorylation of activin receptor
17. TGF-beta signalling from cell membrane to nucleus through SMAD proteins
18. A human Mad protein acting as a BMP-regulated transcriptional activator
19. Smads: Transcriptional activators of TGF-β responses
20. MADR1, a MAD-related protein that functions in BMP2 signaling pathways
21. The TGF-beta family mediator Smad1 is phosphorylated directly and
22. Partnership between DPC4 and SMAD proteins in TGF-beta signalling
23. Xenopus Mad proteins transduce distinct subsets of signals for the TGF
24. Xenopus mothers against decapentaplegic is an embryonic ventralizing
25. Smad5 induces ventral fates in Xenopus embryo
26. Smad8 mediates the signaling of the ALK-2 (corrected) receptor serine
27. Xom: A Xenopus homeobox gene that mediates the early effects of BMP-4
28. Antagonizing the Spemann organizer: Role of the homeobox gene Xvent-1
29. Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4
30. Drosophila Mad binds to DNA and directly mediates activation of vestigial by decapentaplegic
31. Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
32. Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
33. Diversity and pattern in the developing spinal cord
34. Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4
35. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4
36. The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor
37. Alternative neural crest cell fates are instructively promoted by TGF-β superfamily members
38. Cytokines and neuronal differentiation
39. Cytokines regulate the cellular phenotype of developing neural lineage species
40. Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells
41. Growth factor regulation of neuronal development
42. Expression of serine/threonine kinase receptors including the bone morphogenetic factor type II receptor in the developing and adult rat brain
43. Involvement of bone morphogenetic protein-4 and bone morphogenetic protein-7 in the differentiation of the adrenergic phenotype in developing sympathetic neurons
44. Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons
45. Cell lineage determination and the control of neuronal identity in the neural crest
46. Neuropoietic cytokines and activin A differentially regulate the phenotype of cultured sympathetic neurons
47. Depolarization differentially regulates the effects of bone morphogenetic protein (BMP)-2, BMP-6, and activin A on sympathetic neuronal phenotype
48. Activins as candidate cholinergic differentiation factors in vivo
49. Spinal cord neuronal precursors generate multiple neuronal phenotypes in culture
50. Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9
51. Neuronal differentiation of precursors in the neocortical ventricular zone is triggered by BMP
52. Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development
53. Developmental alteration and neuron-specific expression of bone morphogenetic protein-6 (BMP-6) mRNA in rodent brain
54. Sonic hedgehog and BMP2 exert opposing actions on proliferation and differentiation of embryonic neural progenitor cells
55. Noggin acts downstream of Wnt and Sonic Hedgehog to antagonize BMP4 in avian somite patterning
56. Noggin is a negative regulator of neuronal differentiation in developing neocortex
57. Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis
58. Development of brain morphogenetic protein receptors in the nervous system and possible roles in regulation of trkC expression
59. Hybridization histochemical localization of activin receptor subtypes in rat brain, pituitary, ovary, and testis
60. Expression of serine/threonine kinase receptors in traumatic brain injury
61. Molecular cloning of a novel type I receptor serine/threonine kinase for the TGF beta superfamily from rat brain
62. Choline and cholinergic neurons
63. Identification and characterization of the high-affinity choline transporter
64. Selective localization of a high affinity choline uptake system and its role in ACh formation in cholinergic nerve terminals
65. Choline uptake systems of rat brain synaptosomes
66. Acetylcholine transport: Fundamental properties and effects of pharmacologic agents
67. Proteins of synaptic vesicles involved in exocytosis and membrane recycling
68. Heterogeneity of presynaptic muscarinic receptors involved in modulation of transmitter release
69. Ontogeny of cholinergic neurons in the mouse forebrain
70. Neurogenesis of the basal forebrain in euploid and trisomy 16 mice: An animal model for developmental disorders in Down syndrome
71. Time of origin of cholinergic neurons in the rat basal forebrain
72. The cholinergic neuronal differentiation factor from heart cells is identical to leukemia inhibitory factor
73. Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions
74. Regulation of TrkA and ChAT expression in developing rat basal forebrain: Evidence that both exogenous and endogenous NGF regulate differentiation of cholinergic neurons
75. Activation of TrkA by NGF upregulates expression of the cholinergic gene locus but attenuates the response to CNTF
76. Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons
77. Ciliary neurotrophic factor prevents neuronal degeneration and promotes low affinity NGF receptor expression in the adult rat CNS
78. Coregulation of two embedded gene products, choline acetyltransferase and the vesicular acetylcholine transporter
79. Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture
80. Identification of basic fibroblast growth factor as a cholinergic growth factor from human muscle
81. Purification of a skeletal muscle polypeptide which stimulates choline acetyltransferase activity in cultured spinal cord neurons
82. Partial purification and characterization of a membrane-derived factor regulating neurotransmitter phenotypic expression
83. Characterization of a target-derived neuronal cholinergic differentiation factor
84. Interleukin 3 as a trophic factor for central cholinergic neurons in vitro and in vivo
85. Trophic effect of granulocyte-macrophage colony-stimulating factor on central cholinergic neurons in vitro
86. Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system
87. Regulation of the heparan sulfate proteoglycan, perlecan, by injury and interleukin-1α
88. Activin co-operates with fibroblast growth factor 2 to regulate tyrosine hydroxylase expression in the basal forebrain ventricular zone progenitors
89. Identification of a neural stem cell in the adult mammalian central nervous system
90. Distribution of bone morphogenetic protein and bone morphogenetic protein receptor transcripts in the rodent nervous system and upregulation of bone morphogenetic protein receptor type II in hippocampal dentate gyrus in a rat model of global cerebral ischemia
91. Osteogenic protein-1 protects against cerebral infarction induced by MCA ligation in adult rats