Effect of a novel NK1 receptor selective antagonist (NKP608) on citric acid induced cough and airway obstruction

Pulmonary Pharmacology and Therapeutics

Volumn 17, Issue 1, 2004, Pages 11-18

  El Hashim, A Z ^b   Wyss, D ^a   Lewis, C ^a  

^a NOVARTIS HORSHAM RESEARCH CENTRE   (United Kingdom)

^b KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Airway obstruction; Citric acid; Cough; Guinea pigs; Plethysmography

Indexed keywords

CITRIC ACID; NEUROKININ 1 RECEPTOR ANTAGONIST; NKP 608; SAREDUTANT; BENZAMIDE DERIVATIVE; NEUROKININ 1 RECEPTOR; PIPERIDINE DERIVATIVE; QUINOLINE 4 CARBOXYLIC ACID (1 (3,5 BIS TRIFLUOROMETHYLBENZOYL) 2 (4 CHLOROBENZYL)PIPERIDIN 4 YL)AMIDE; QUINOLINE DERIVATIVE; QUINOLINE-4-CARBOXYLIC ACID (1-(3,5-BIS-TRIFLUOROMETHYLBENZOYL)-2-(4-CHLOROBENZYL)PIPERIDIN-4-YL)AMIDE;

AIRWAY OBSTRUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; COUGHING; DOSE RESPONSE; DRUG EFFECT; GUINEA PIG; MALE; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM;

AIRWAY OBSTRUCTION; ANIMALS; BENZAMIDES; CITRIC ACID; COUGH; GUINEA PIGS; MALE; PIPERIDINES; PLETHYSMOGRAPHY; QUINOLINES; RECEPTORS, NEUROKININ-1;

EID: 0344552290     PISSN: 10945539     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pupt.2003.08.002     Document Type: Article

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