Development, maintenance, and function of the adrenal gland in early postnatal proopiomelanocortin-null mutant mice

Endocrinology

Volumn 146, Issue 6, 2005, Pages 2555-2562

  Karpac, Jason ^a   Ostwald, Dirk ^a   Bui, Stephanie ^a   Hunnewell, Peggy ^a   Shankar, Malini ^a   Hochgeschwender, Ute ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; CATECHOLAMINE; CORTICOSTERONE; CORTICOTROPIN; GLUCOCORTICOID; MINERALOCORTICOID; PROOPIOMELANOCORTIN;

ADRENAL CELL; ADRENAL CORTEX ATROPHY; ADRENAL FUNCTION; ADRENAL GLAND; ADRENALECTOMY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MUTANT; CELL PROLIFERATION; CORTICOSTERONE RELEASE; HORMONE SYNTHESIS; MOUSE; NONHUMAN; PERINATAL PERIOD; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; WILD TYPE;

ADRENAL GLAND DISEASES; ADRENAL GLANDS; ADRENALECTOMY; ANIMALS; ANIMALS, NEWBORN; CELL DIFFERENTIATION; CELL DIVISION; CORTICOSTERONE; HOMOZYGOTE; MICE; MICE, MUTANT STRAINS; PRO-OPIOMELANOCORTIN;

EID: 18844442086     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2004-1290     Document Type: Article

References (50)

1. Mains RE, Eipper BA 1979 Studies of peptide hormone biosynthesis and structure: ACTH, endorphin, and related molecules. Symp Soc Exp Biol 33:37-55
2. Bertagna X 1994 Proopiomelanocortin-derived peptides. Endocrinol Metab Clin North Am 23:467-485
3. Raffin-Sanson ML, de Keyzer Y, Bertagna X 2003 Proopiomelanocortin, a polypeptide precursor with multiple functions: from physiology to pathological conditions. Eur J Endocrinol 149:79-90
4. Farese RV 1968 Regulation of adrenal growth and steroidogenesis by ACTH. In: McKerns KW, ed. Functions of the adrenal cortex. New York: Appleton-Century-Crofts; 549-562
5. Gill GN 1972 Mechanism of ACTH action. Metabolism 21:571-588
6. Muglia L, Jacobson L, Dikkes P, Majzoub JA 1995 Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature 373:427-432
7. Smith GW, Aubry JM, Dellu F, Contarino A, Bilezikjian LM, Gold LH, Chen R, Marchuk Y, Hauser C, Bentley CA, Sawchenko PE, Koob GF, Vale W, Lee KF 1998 Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development. Neuron 20:1093-1102
8. Timpl P, Spanagel R, Sillaber I, Kresse A, Reul JM, Stalla GK, Blanquet V, Steckler T, Holsboer F, Wurst W 1998 Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1. Nat Genet 19:162-166
9. Allen RG, Carey C, Parker JD, Mortrud MT, Mellon SH, Low MJ 1995 Targeted ablation of pituitary pre-proopiomelanocortin cells by herpes simplex virus-1 thymidine kinase differentially regulates mRNAs encoding the adrenocorticotropin receptor and aldosterone synthase in the mouse adrenal gland. Mol Endocrinol 9:1005-1016
10. Pulichino AM, Vallette-Kasic S, Couture C, Gauthier Y, Brue T, David M, Malpuech G, Deal C, Van Vliet G, De Vroede M, Riepe FG, Partsch CJ, Sippell WG, Berberoglu M, Atasay B, Drouin J 2003 Human and mouse TPIT gene mutations cause early onset pituitary ACTH deficiency. Genes Dev 17:711-716
11. Cole TJ, Blendy JA, Monaghan AP, Krieglstein K, Schmid W, Aguzzi A, Fantuzzi G, Hummler E, Unsicker K, Schutz G 1995 Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev 9:1608-1621
12. Clark AJ, Weber A 1998 Adrenocorticotropin insensitivity syndromes. Endocr Rev 19:828-843
13. Estivariz FE, Iturriza F, McLean C, Hope J, Lowry PJ 1982 Stimulation of adrenal mitogenesis by N-terminal proopiocortin peptides. Nature 297:419-422
14. Lowry PJ, Silas L, McLean C, Linton EA, Estivariz FE 1983 Pro-γ-melanocyte-stimulating hormone cleavage in adrenal gland undergoing compensatory growth. Nature 306:70-73
15. Estivariz FE, Carino M, Lowry PJ, Jackson S 1988 Further evidence that N-terminal pro-opiomelanocortin peptides are involved in adrenal mitogenesis. J Endocrinol 116:201-206
16. Estivariz FE, Morano MI, Carino M, Jackson S, Lowry PJ 1988 Adrenal regeneration in the rat is mediated by mitogenic N-terminal pro- opiomelanocortin peptides generated by changes in precursor processing in the anterior pituitary. J Endocrinol 116:207-216
17. Bicknell AB, Lomthaisong K, Woods RJ, Hutchinson EG, Bennett HP, Gladwell RT, Lowry PJ 2001 Characterization of a serine protease that cleaves pro-γ-melanotropin at the adrenal to stimulate growth. Cell 105:903-912
18. Fassnacht M, Hahner S, Hansen IA, Kreutzberger T, Zink M, Adermann K, Jakob F, Troppmair J, Allolio B 2003 N-terminal proopiomelanocortin acts as a mitogen in adrenocortical tumor cells and decreases adrenal steroidogenesis. J Clin Endocrinol Metab 88:2171-2179
19. Pedersen RC, Brownie AC 1980 Adrenocortical response to corticotropin is potentiated by part of the amino-terminal region of pro-corticotropin/endorphin. Proc Natl Acad Sci USA 77:2239-2243
20. Pedersen RC, Brownie AC, Ling N 1980 Pro-adrenocorticotropin/endorphin- derived peptides: coordinate action on adrenal steroidogenesis. Science 208:1044-1046
21. Al-Dujaili EA, Hope J, Estivariz FE, Lowry PJ, Edwards CR 1981 Circulating human pituitary pro-γ-melanotropin enhances the adrenal response to ACTH. Nature 291:156-159
22. Al-Dujaili EA, Williams BC, Edwards CR, Salacinski P, Lowry PJ 1982 Human γ-melanotropin precursor potentiates corticotropin-induced adrenal steroidogenesis by stimulating mRNA synthesis. Biochem J 204:301-305
23. Pedersen RC, Brownie AC 1987 γ3-Melanotropin promotes mitochondrial cholesterol accumulation in the rat adrenal cortex. Mol Cell Endocrinol 50:149-156
24. Baird A, Kan KW, Solomon S 1983 Role of pro-opiomelanocortin-derived peptides in the regulation of steroid production by human fetal adrenal cells in culture. J Endocrinol 97:357-367
25. Szalay KS 1993 Effects of pro-opiomelanocortin peptides on adrenocortical steroidogenesis. J Steroid Biochem Mol Biol 45:141-146
26. Vinson GP, Whitehouse BJ, Dell A, Etienne T, Morris HR 1980 Characterisation of an adrenal zona glomerulosa-stimulating component of posterior pituitary extracts as α-MSH. Nature 284:464-467
27. Bateman A, Dell A, Whitehouse BJ, Vinson GP 1986 Non-ACTH components of adult human pituitary extracts which stimulate adrenal steroidogenesis. Neuropeptides 7:381-390
28. Yaswen L, Diehl N, Brennan MB, Hochgeschwender U 1999 Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. Nat Med 5:1066-1070
29. Challis BG, Coll AP, Yeo GS, Pinnock SB, Dickson SL, Thresher RR, Dixon J, Zahn D, Rochford JJ, White A, Oliver RL, Millington G, Aparicio SA, Colledge WH, Russ AP, Carlton MB, O'Rahilly S 2004 Mice lacking proopiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36). Proc Natl Acad Sci USA 101:4695-4700
30. Coll AP, Challis BG, Yeo GS, Snell K, Piper SJ, Halsall D, Thresher RR, O'Rahilly S 2004 The effects of proopiomelanocortin deficiency on murine adrenal development and responsiveness to adrenocorticotropin. Endocrinology 145:4721-4727
31. Costa JL, Bui S, Reed P, Dores RM, Brennan MB, Hochgeschwender U 2004 Mutational analysis of evolutionarily conserved ACTH residues. Gen Comp Endocrinol 136:12-16
32. Wilkinson CW, Shinsako J, Dallman MF 1981 Return of pituitary-adrenal function after adrenal enucleation or transplantation: diurnal rhythms and responses to ether. Endocrinology 109:162-169
33. Gibson MJ, Krieger DT 1981 Circadian corticosterone rhythm and stress response in rats with adrenal autotransplants. Am J Physiol 240:E363-E366
34. Engeland WC 1984 Plasma adrenocorticotropin concentration is elevated in adult rats with neonatal adrenal transplants. Endocrinology 114:2160-2166
35. Coulter CL, Young IR, Browne CA, McMillen IC 1989 Effect of hypophysectomy on the growth and development of the sheep adrenal gland: a morphometric study. Acta Endocrinol (Copenh) 120:301-307
36. Nicolle A, Bosc MJ 1990 A quantitative histological study of adrenal development during late gestation and the perinatal period in intact and hypophysectomized fetal sheep. Reprod Nutr Dev 30:653-662
37. Nicolle A, Bosc MJ 1989 A quantitative histological study of adrenal development during the perinatal period in intact and hypophysectomized pigs. Reprod Nutr Dev 29:283-291
38. Hristic M, Kalafatic D, Plecas B, Manojlovic M 1997 The influence of prolonged dexamethasone treatment of pregnant rats on the perinatal development of the adrenal gland of their offspring. J Exp Zool 279:54-61
39. Manojlovic M, Kalafatic D, Hristic M, Plecas B, Virag A, Cakic M 1998 Treatment of pregnant females with dexamethasone influences postnatal development of the adrenal medulla. Anat Anz 180:131-135
40. Wyllie AH, Kerr JF, Currie AR 1973 Cell death in the normal neonatal rat adrenal cortex. J Pathol 111:255-261
41. Wyllie AH, Ken JF, Macaskill IA, Currie AR 1973 Adrenocortical cell deletion: the role of ACTH. J Pathol 111:85-94
42. Tchen TT, Chan SW, Kuo TH, Mostafapour KM, Drzewiecki VH 1977 Studies on the adrenal cortex of hypophysectomized rats: a model for abnormal cellular atrophy and death. Mol Cell Biochem 15:79-87
43. Krude H, Gruters A 2000 Implications of proopiomelanocortin (POMC) mutations in humans: the POMC deficiency syndrome. Trends Endocrinol Metab 11:15-22
44. Engeland WC 1986 Pituitary-adrenal function after transplantation in rats: dependence on age of the adrenal graft. Am J Physiol 250:E87-E93
45. Smart JL, Low MJ 2003 Lack of proopiomelanocortin peptides results in obesity and defective adrenal function but normal melanocyte pigmentation in the murine C57BL/6 genetic background. Ann NY Acad Sci 994:202-210
46. Muglia LJ, Jacobson L, Luedke C, Vogt SK, Schaefer ML, Dikkes P, Fukuda S, Sakai Y, Suda T, Majzoub JA 2000 Corticotropin-releasing hormone links pituitary adrenocorticotropin gene expression and release during adrenal insufficiency. J Clin Invest 105:1269-1277
47. Laurent V, Kimble A, Peng B, Zhu P, Pintar JE, Steiner DF, Lindberg I 2002 Mortality in 7B2 null mice can be rescued by adrenalectomy: involvement of dopamine in ACTH hypersecretion. Proc Natl Acad Sci USA 99:3087-3092
48. Cheifetz PN 1971 The daily rhythm of the secretion of corticotrophin and corticosterone in rats and mice. J Endocrinol 49:xi-xii
49. Walker CD, Akana SF, Cascio CS, Dallman MF 1990 Adrenalectomy in the neonate: adult-like adrenocortical system responses to both removal and replacement of corticosterone. Endocrinology 127:832-842
50. Goshen I, Yirmiya R, Iverfeldt K, Weidenfeld J 2003 The role of endogenous interleukin-1 in stress-induced adrenal activation and adrenalectomy-induced adrenocorticotropic hormone hypersecretion. Endocrinology 144:4453-4458