Elongating modified conserved peptides eliminates their immunogenicity and protective efficacy against P. falciparum malaria

Journal of Structural Biology

Volumn 150, Issue 3, 2005, Pages 245-258

  Espejo, Fabiola ^a   Bermúdez, Adriana ^a   Vanegas, Magnolia ^a   Rivera, Zuly ^a   Torres, Elizabeth ^a   Salazar, Luz Mary ^a,b   Patarroyo, Manuel Elkin ^a,b  

^a FUNDACIÓN INSTITUTO DE INMUNOLOGÍA DE COLOMBIA FIDIC   (Colombia)

^b UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

Author keywords

Elongated peptide; HLA DR 1*; Malaria; NMR; Structural calculations

Indexed keywords

AMINO ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; AOTUS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; HUMORAL IMMUNITY; IMMUNOASSAY; IMMUNOFLUORESCENCE TEST; IMMUNOGENICITY; INOCULATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALARIA; MONKEY; NONHUMAN; PARASITE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; RNA TRANSLATION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; AOTUS TRIVIRGATUS; BINDING, COMPETITIVE; BLOTTING, WESTERN; CIRCULAR DICHROISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; HLA-DR ANTIGENS; HUMANS; MACROMOLECULAR SUBSTANCES; MAGNETIC RESONANCE SPECTROSCOPY; MALARIA VACCINES; MALARIA, FALCIPARUM; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

PLASMODIUM FALCIPARUM;

EID: 18844412665     PISSN: 10478477     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsb.2005.03.007     Document Type: Article

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