Distorting malaria peptide backbone structure to enable fitting into MHC class II molecules renders modified peptides immunogenic and protective

Journal of Medicinal Chemistry

Volumn 46, Issue 11, 2003, Pages 2250-2253

  Cifuentes, Gladys ^a   Patarroyo, Manuel Elkin ^a,b   Urquiza, Mauricio ^a,b   Ramirez, Luis E ^a   Reyes, Claudia ^a   Rodriguez, Raul ^a  

^a FUNDACIÓN INSTITUTO DE INMUNOLOGÍA DE COLOMBIA FIDIC   (Colombia)

^b UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MALARIA VACCINE; MEROZOITE SURFACE PROTEIN 2; PEPTIDE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ERYTHROCYTE; IMMUNE SYSTEM; IMMUNIZATION; IMMUNOGENICITY; MALARIA; MONKEY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN STRUCTURE;

ANIMALS; ANTIGENS, PROTOZOAN; AOTIDAE; HISTOCOMPATIBILITY ANTIGENS CLASS II; MAGNETIC RESONANCE SPECTROSCOPY; MALARIA, FALCIPARUM; MODELS, MOLECULAR; PEPTIDES; PLASMODIUM FALCIPARUM; PROTEIN CONFORMATION; PROTOZOAN PROTEINS; VACCINATION;

EID: 0038075455     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020440w     Document Type: Article

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