Synthesis and activity of C11-modified wortmannin probes for PI3 kinase

Bioconjugate Chemistry

Volumn 16, Issue 3, 2005, Pages 669-675

  Yuan, Hushan ^a,b   Luo, Ji ^b   Field, Seth ^b   Weissleder, Ralph ^a,b   Cantley, Lewis ^b   Josephson, Lee ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL RESEARCH; ENZYMES;

BIOLOGICAL FUNCTIONS; BIOLOGICAL RESEARCH; CLINICAL SETTINGS; HIGH SPECIFICITY; IMMUNOPRECIPITATES; IN-VIVO; PI3-KINASE; SPECIFIC INHIBITORS; SYNTHESISED; WORTMANNIN;

PROBES;

4 HYDROXY 3 IODOPHENYL WORTMANNIN; BIOTINYLATED WORTMANNIN; DRUG DERIVATIVE; FLUORESCEIN DERIVATIVE; FLUORESCEIN WORTMANNIN; IODINE 125; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; BIOTINYLATION; DRUG ACTIVITY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME BINDING; ENZYME INHIBITION;

EID: 18844372004     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc049714f     Document Type: Article

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