Novel reversible, irreversible and fluorescent inhibitors of platelet- activating factor acetylhydrolase as mechanistic probes

Atherosclerosis

Volumn 144, Issue 1, 1999, Pages 79-90

  Deigner, Hans P ^a   Kinscherf, Ralf ^a   Claus, Ralf ^a   Fyrnys, Beatrix ^a   Blencowe, Christopher ^a   Hermetter, A ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

Fluorescence; Inhibitors; Macrophages; Platelet activating factor acetylhydrolase

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; 1 O DECYLOXY [10 (4 PYRENIL)BUTOXY] 2 DESOXY 2 AMINO CARBAMOYLMETHYL GLYCERO 3 PHOSPHOCHOLINE; 1 O HEXADECYL 2 DESOXY 2 AMINOMETHYLCARBAMOYL 2 METHYL GLYCERO 3 PHOSPHOCHOLINE; ETHER PHOSPHOLIPID; GLYCEROL; PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MONOCYTE; PRIORITY JOURNAL; PROTEIN INTERACTION; STOICHIOMETRY;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; BINDING SITES; BIOLOGICAL MARKERS; CELLS, CULTURED; DRUG INTERACTIONS; FLUORESCENT DYES; HUMANS; MACROPHAGES; PHOSPHOLIPASES A; PLATELET ACTIVATING FACTOR; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032974586     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(99)00034-9     Document Type: Article

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