Serotonin and noradrenaline modulate respiratory pattern disturbances evoked by glutamate injection into the pedunculopontine tegmentum of anesthetized rats

Sleep

Volumn 28, Issue 5, 2005, Pages 560-570

  Saponjic, Jasna ^a,d   Cvorovic, Jovana ^b   Radulovacki, Miodrag ^b   Carley, David W ^a,b,c  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c University of Illinois at Chicago   (United States)

^d Institute of Critical Care Medicine   (United States)

Author keywords

Noradrenaline; Pedunculopontine tegmental nucleus; Respiratory disturbance; Serotonin

Indexed keywords

GLUTAMIC ACID; NORADRENALIN; SEROTONIN;

ANESTHESIA INDUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APNEA; ARTICLE; BEHAVIOR; BREATHING; DISEASE DURATION; MONOAMINERGIC SYSTEM; NEUROMODULATION; NONHUMAN; PEDUNCULOPONTINE TEGMENTAL NUCLEUS; PRIORITY JOURNAL; RAT; REM SLEEP; RESPIRATION CONTROL; RESPIRATORY FAILURE; RESPIRATORY FUNCTION; SEROTONINERGIC NERVE CELL;

EID: 18744397543     PISSN: 01618105     EISSN: None     Source Type: Journal    
DOI: 10.1093/sleep/28.5.560     Document Type: Article

References (49)

1. Datta S, Patterson EH, Spoley EE. Excitation of the pedunculopontine tegmental NMDA receptors induces wakefulness and cortical activation in the rat. J Neurosci Res 2001;66:109-16.
2. Balatoni B, Detari L. EEG related neuronal activity in the pedunculopontine tegmental nucleus of urethane anaesthetized rats. Brain Res 2003;959:304-11.
3. Steriade M, Amzica F, Nunez A. Cholinergic and noradrenergic modulation of the slow (approximately 0.3 Hz) oscillation in neocortical cells. J Neurophysiol 1993;70:1385-400.
4. Bland BH, Oddie SD. Anatomical, electrophysiological and pharmacological studies of ascending brainstem hippocampal synchronizing pathways. Neurosci Biobehav Rev 1998;22:259-73.
5. Vertes RP, Colom LV, Fortin WJ, Bland BH. Brainstem sites for the carbachol elicitation of the hippocampal theta rhythm in the rat. Exp Brain Res 1993;96:419-29.
6. Datta S, Calvo JM, Quattrochi J, Hobson JA. Cholinergic microstimulation of the peribrachial nucleus in the cat. 1. Immediate and prolonged increases in ponto-geniculo-occipital waves. Arch Ital Biol 1992;130:263-84.
7. Datta S. Cellular basis of pontine ponto-geniculo-occipital wave generation and modulation. Cell Mol Neurobiol 1997;17:341-65.
8. Datta S, Siwek DF. Single cell activity patterns of pedunculopontine tegmentum neurons across the sleep-wake cycle in the freely moving rats. J Neurosci Res 2002;70:611-21.
9. Shouse MN, Siegel JM. Pontine regulation of REM sleep components in cats: integrity of the pedunculopontine tegmentum (PPT) is important for phasic events but unnecessary for atonia during REM sleep. Brain Res 1992;571:50-63.
10. Steriade M, McCarley R. Brainstem Control of Wakefulness and Sleep New York: Plenum Press; 1990.
11. Radulovacki M, Carley D. The laboratory rat as a model of sleep-related breathing disorders. In: Carley D, Radulovacki M, eds. Sleep-Related Breathing Disorders: Experimental Models and Therapeutic Potential. New York: Marcel Dekker; 2002:3-16.
12. Datta S, Spoley EE, Patterson EH. Microinjection of glutamate into the pedunculopontine tegmentum induces REM sleep and wakefulness in the rat.am J Physiol 2001;280:R752-9.
13. Carley DW, Radulovacki M. REM sleep and apnea. In: Mallick BN, Inoue S, eds. Rapid Eye Movement Sleep. New Delhi: Narosa Publishing; 1999:286-300.
14. Saponjic J, Radulovacki M, Carley DW. Respiratory pattern modulation by the pedunculopontine tegmental nucleus. Respir Physiol Neurobiol 2003;138:223-37.
15. Saponjic J, Radulovacki M, Carley DW. P-waves are coupled to long-lasting respiratory disturbance following glutamate stimulation of the pedunculo-pontine tegmental nucleus (PPT). Sleep 2003;26:A45-6.
16. Lydic R, Baghdoyan HA. Pedunculopontine stimulation alters respiration and increases ACh release in the pontine reticular formation.am J Physiol 1993;264:R544-54.
17. Leonard CS, Llinas R. Serotonergic and cholinergic inhibition of mesopontine cholinergic neurons controlling REM sleep: an in vitro electrophysiological study. Neuroscience 1994;59:309-30.
18. Semba K, Fibiger HC. Afferent connections of the laterodorsal and the pedunculopontine tegmental nuclei in the rat: a retro- and antero-grade transport and immunohistochemical study. J Comp Neurol 1992;323:387-410.
19. Jones BE. Paradoxical sleep and its chemical/structural substrates in the brain. Neuroscience 1991;40:637-56.
20. Hobson JA, McCarley RW, Wyzinski PW. Sleep cycle oscillation: reciprocal discharge by two brainstem neuronal groups. Science 1975;189:55-8.
21. Thakkar MM, Strecker RE, McCarley RW. Behavioral state control through differential serotonergic inhibition in the mesopontine cholinergic nuclei: a simultaneous unit recording and microdialysis study. J Neurosci 1998;18:5490-7.
22. Steininger TL, Wainer BH, Blakely RD, Rye DB. Serotonergic dorsal raphe nucleus projections to the cholinergic and noncholinergic neurons of the pedunculopontine tegmental region: a light and electron microscopic anterograde tracing and immunohistochemical study. J Comp Neurol 1997;382:302-22.
23. Rye DB, Saper CB, Lee HJ, Wainer BH. Pedunculopontine tegmental nucleus of the rat: cytoarchitecture, cytochemistry, and some extrapyramidal connections of the mesopontine tegmentum. J Comp Neurol 1987;259:483-528.
24. Paxinos G, and Watson, C. The Rat Brain in Stereotaxic Coordinates. 4th ed San Diego: Academic Press; 1998.
25. Luebke JI, Greene RW, Semba K, Kamondi A, McCarley RW, Reiner PB. Serotonin hyperpolarizes cholinergic low-threshold burst neurons in the rat laterodorsal tegmental nucleus in vitro. Proc Natl Acad Sci U S A 1992;89:743-7.
26. Aston-Jones G, Bloom FE. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J Neurosci 1981;1:876-86.
27. McGinty DJ, Harper RM. Dorsal raphe neurons: depression of firing during sleep in cats. Brain Res 1976;101:569-75.
28. Datta S. Neuronal activity in the peribrachial area: relationship to behavioral state control. Neurosci Biobehav Rev 1995;19:67-84.
29. Radulovacki M, Pavlovic S, Saponjic J, Carley DW. Modulation of reflex and sleep related apnea by pedunculopontine tegmental and intertrigeminal neurons. Respir Physiol Neurobiol 2004;143:293-306.
30. Datta S, Mavanji V, Patterson EH, Ulloor J. Regulation of rapid eye movement sleep in the freely moving rat: local microinjection of serotonin, norepinephrine, and adenosine into the brainstem. Sleep 2003;26:513-20.
31. Holmes CJ, Jones BE. Importance of cholinergic, GABAergic, serotonergic and other neurons in the medial medullary reticular formation for sleep-wake states studied by cytotoxic lesions in the cat. Neuroscience 1994;62:1179-200.
32. Dunbar JS, Hitchcock K, Latimer M, Rugg EL, Ward N, Winn P. Excitotoxic lesions of the pedunculopontine tegmental nucleus of the rat. II. Examination of eating and drinking, rotation, and reaching and grasping following unilateral ibotenate or quinolinate lesions. Brain Res 1992;589:194-206.
33. Chamberlin NL, Saper CB. Topographic organization of respiratory responses to glutamate microstimulation of the parabrachial nucleus in the rat. J Neurosci 1994;14:6500-10.
34. Kubin L, Fenik, F. Pontine cholinergic mechanisms and their impact on respiratory regulation. Respir Physiol Neurobiol 2004;143:235-49.
35. Clements JR, Grant S. Glutamate-like immunoreactivity in neurons of the laterodorsal tegmental and pedunculopontine nuclei in the rat. Neurosci Lett 1990;120:70-3.
36. Lai YY, Clements JR, Siegel JM. Glutamatergic and cholinergic projections to the pontine inhibitory area identified with horseradish peroxidase retrograde transport and immunohistochemistry. J Comp Neurol 1993;336:321-30.
37. Lavoie B, Parent A. Pedunculopontine nucleus in the squirrel monkey: distribution of cholinergic and monoaminergic neurons in the mesopontine tegmentum with evidence for the presence of glutamate in cholinergic neurons. J Comp Neurol 1994;344:190-209.
38. Grofova I, Zhou M. Nigral innervation of cholinergic and glutamatergic cells in the rat mesopontine tegmentum: light and electron microscopic anterograde tracing and immunohistochemical studies. J Comp Neurol 1998;395:359-79.
39. Rye DB. Contributions of the pedunculopontine region to normal and altered REM sleep. Sleep 1997;20:757-88.
40. Steininger TL, Rye DB, Wainer BH. Afferent projections to the cholinergic pedunculopontine tegmental nucleus and adjacent midbrain extrapyramidal area in the albino rat. I. Retrograde tracing studies. J Comp Neurol 1992;321:515-43.
41. Monnier A, Alheid GF, McCrimmon DR. Defining ventral medullary respiratory compartments with a glutamate receptor agonist in the rat. J Physiol 2003;548:859-74.
42. Nicholson C. Diffusion from an injected volume of a substance in brain tissue with arbitrary volume fraction and tortuosity. Brain Res 1985;333:325-9.
43. Lydic R, Baghdoyan HA. Ketamine and MK-801 decrease acetyl-choline release in the pontine reticular formation, slow breathing, and disrupt sleep. Sleep 2002;25:617-22.
44. Honda T, Semba K. Serotonergic synaptic input to cholinergic neurons in the rat mesopontine tegmentum. Brain Res 1994;647:299-306.
45. Kubota Y, Leung E, Vincent SR. Ultrastructure of cholinergic neurons in the laterodorsal tegmental nucleus of the rat: interaction with catecholamine fibers. Brain Res Bull 1992;29:479-91.
46. Honda T, Semba K. An ultrastructural study of cholinergic and non-cholinergic neurons in the laterodorsal and pedunculopontine tegmental nuclei in the rat. Neuroscience 1995;68:837-53.
47. Williams JA, Reiner PB. Noradrenaline hyperpolarizes identified rat mesopontine cholinergic neurons in vitro. J Neurosci 1993;13:3878-83.
48. Hou YP, Manns ID, Jones BE. Immunostaining of cholinergic pontomesencephalic neurons for alpha 1 versus alpha 2 adrenergic receptors suggests different sleep-wake state activities and roles. Neuroscience 2002;114:517-21.
49. Kohlmeier KA, Reiner PB. Noradrenaline excites non-cholinergic laterodorsal tegmental neurons via two distinct mechanisms. Neuroscience 1999;93:619-30.