-
1
-
-
0034619328
-
Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracranial gliomas
-
Aboody, K.; Brown, A.; Rainov, N. G.; Bower, K. A.; Liu, S.; Yang, W.; Small, J.; Herrlinger, U.; Ourednik, V.; Black, P. M.; Breakfield, X.; Snyder, E. Y. Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracranial gliomas. Proc. Nat. Acad. Sci. USA 97:12846-12851; 2000.
-
(2000)
Proc. Nat. Acad. Sci. USA
, vol.97
, pp. 12846-12851
-
-
Aboody, K.1
Brown, A.2
Rainov, N.G.3
Bower, K.A.4
Liu, S.5
Yang, W.6
Small, J.7
Herrlinger, U.8
Ourednik, V.9
Black, P.M.10
Breakfield, X.11
Snyder, E.Y.12
-
2
-
-
0025893945
-
Parkinson's disease: Pathophysiology
-
Agid, Y. Parkinson's disease: Pathophysiology. Lancet 337:1321-1324; 1991.
-
(1991)
Lancet
, vol.337
, pp. 1321-1324
-
-
Agid, Y.1
-
3
-
-
0028169809
-
Neural-targeted gene therapy for rodent and primate hemiparkinsonism
-
Anton, R.; Kordower, J. H.; Maidment, N. T.; Manaster, J. S.; Kane, D. J.; Rabizadeh, S.; Schueller, S. B.; Yang, J.; Edards, R. H.; Markham, C. H.; Bredesen, D. E. Neural-targeted gene therapy for rodent and primate hemiparkinsonism. Exp. Neurol. 127:207-218; 1994.
-
(1994)
Exp. Neurol.
, vol.127
, pp. 207-218
-
-
Anton, R.1
Kordower, J.H.2
Maidment, N.T.3
Manaster, J.S.4
Kane, D.J.5
Rabizadeh, S.6
Schueller, S.B.7
Yang, J.8
Edards, R.H.9
Markham, C.H.10
Bredesen, D.E.11
-
4
-
-
0030006065
-
Double transduction with GTP cyclohydrolasel and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts
-
Bencsics, C.; Wachtel, S. R.; Milstien, S.; Hatakeyama, K.; Becker, J. B.; Kang, U. J. Double transduction with GTP cyclohydrolasel and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts. J. Neurosci. 16:4449-4456; 1996.
-
(1996)
J. Neurosci.
, vol.16
, pp. 4449-4456
-
-
Bencsics, C.1
Wachtel, S.R.2
Milstien, S.3
Hatakeyama, K.4
Becker, J.B.5
Kang, U.J.6
-
5
-
-
0034117480
-
Gene therapy of experimental brain tumors using neural progenitor cells
-
Benedetti, S.; Pirola, B.; Pollo, B.; Magrassi, L.; Bruzzone, M. G.; Rigamonti, D.; Galli, R.; Selleri, S.; Di Meco, F.; De Fraja, C.; Vescovi, A.; Cattaneo, E.; Finocchiaro, G. Gene therapy of experimental brain tumors using neural progenitor cells. Nat. Med. 6:447-450; 2000.
-
(2000)
Nat. Med.
, vol.6
, pp. 447-450
-
-
Benedetti, S.1
Pirola, B.2
Pollo, B.3
Magrassi, L.4
Bruzzone, M.G.5
Rigamonti, D.6
Galli, R.7
Selleri, S.8
Di Meco, F.9
De Fraja, C.10
Vescovi, A.11
Cattaneo, E.12
Finocchiaro, G.13
-
6
-
-
0034032642
-
Cell replacement therapies for central nervous system disorders
-
Björklund, A.; Lindvall, O. Cell replacement therapies for central nervous system disorders. Nat. Neurosci. 3:537-544; 2000.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 537-544
-
-
Björklund, A.1
Lindvall, O.2
-
7
-
-
0030273384
-
Neuronal progenitors as tools for cell replacement in the nervous system
-
Brüstle, O.; McKay, R. D. G. Neuronal progenitors as tools for cell replacement in the nervous system. Curr. Opin. Neurobiol. 6:688-695; 1996.
-
(1996)
Curr. Opin. Neurobiol.
, vol.6
, pp. 688-695
-
-
Brüstle, O.1
McKay, R.D.G.2
-
8
-
-
0029047361
-
Temporal pattern of host responses against intrastriatal grafts of syngenic, allogenic or xenogenic embryonic neuronal tissue in rats
-
Duan, W.; Widner, H.; Brundin, P. Temporal pattern of host responses against intrastriatal grafts of syngenic, allogenic or xenogenic embryonic neuronal tissue in rats. Exp. Brain Res. 104:227-242; 2000.
-
(2000)
Exp. Brain Res.
, vol.104
, pp. 227-242
-
-
Duan, W.1
Widner, H.2
Brundin, P.3
-
9
-
-
0028559601
-
Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase
-
During, M. J.; Naegele, J. R.; O'Malley, K. L.; Geller, A. I. Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase. Science 266:1399-1403; 1991.
-
(1991)
Science
, vol.266
, pp. 1399-1403
-
-
During, M.J.1
Naegele, J.R.2
O'Malley, K.L.3
Geller, A.I.4
-
10
-
-
0025963275
-
Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce L-DOPA
-
Fisher, L. J.; Jinnah, H. A.; Kale, L. C.; Higgins, G. A.; Gage, F. H. Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce L-DOPA. Neuron 6:371-380; 1991.
-
(1991)
Neuron
, vol.6
, pp. 371-380
-
-
Fisher, L.J.1
Jinnah, H.A.2
Kale, L.C.3
Higgins, G.A.4
Gage, F.H.5
-
11
-
-
0032495808
-
Dopamine turnover and metabolism in the striatum of parkinsonian rats grafted with genetically modified human astrocytes
-
Fitoussi, N.; Sotnik-Barkai, I.; Tornatore, C.; Herzberg, U.; Yadid, G. Dopamine turnover and metabolism in the striatum of parkinsonian rats grafted with genetically modified human astrocytes. Neuroscience 85:405-413; 1998.
-
(1998)
Neuroscience
, vol.85
, pp. 405-413
-
-
Fitoussi, N.1
Sotnik-Barkai, I.2
Tornatore, C.3
Herzberg, U.4
Yadid, G.5
-
12
-
-
0031771599
-
Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes
-
Flax, J. D.; Aurora, S.; Yang, C.; Simonin, C.; Wills, A. M.; Billinghurst, L. L.; Jendoubi, M.; Sidman, R. L.; Wolfe, J. H.; Kim, S. U.; Snyder, E. Y. Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes. Nat. Biotechnol. 16: 1033-1039; 1998.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 1033-1039
-
-
Flax, J.D.1
Aurora, S.2
Yang, C.3
Simonin, C.4
Wills, A.M.5
Billinghurst, L.L.6
Jendoubi, M.7
Sidman, R.L.8
Wolfe, J.H.9
Kim, S.U.10
Snyder, E.Y.11
-
13
-
-
0034712047
-
Mammalian neural stem cells
-
Gage, F. H. Mammalian neural stem cells. Science 287:1433-1438; 2000.
-
(2000)
Science
, vol.287
, pp. 1433-1438
-
-
Gage, F.H.1
-
14
-
-
0033615096
-
Prospects for the clinical application of neural transplantation with the use of conditionally immortalized neuroepithelial stem cells
-
Gray, J. A.; Hodges, H.; Sinden, J. Prospects for the clinical application of neural transplantation with the use of conditionally immortalized neuroepithelial stem cells. Philos. Trans. R. Soc. Lond. B Biol. Sci. 354:1407-1421; 1999.
-
(1999)
Philos. Trans. R. Soc. Lond. B Biol. Sci.
, vol.354
, pp. 1407-1421
-
-
Gray, J.A.1
Hodges, H.2
Sinden, J.3
-
15
-
-
0026020898
-
Cloning and sequencing of cDNA encoding rat GTP cyclohydrolase I. The first enzyme of the tetrahydrobiopterin biosynthetic pathway
-
Hatakeyama, K.; Inoue, Y.; Harada, T.; Kagamiyama, H. Cloning and sequencing of cDNA encoding rat GTP cyclohydrolase I. The first enzyme of the tetrahydrobiopterin biosynthetic pathway. J. Biol. Chem. 266:765-769; 1991.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 765-769
-
-
Hatakeyama, K.1
Inoue, Y.2
Harada, T.3
Kagamiyama, H.4
-
16
-
-
0025119186
-
In vivo release of DOPA and dopamine from genetically engineered cells grafted to the denervated rat striatum
-
Horellou, P.; Brundin, P.; Kalen, P.; Mallet, J.; Björklund, A. In vivo release of DOPA and dopamine from genetically engineered cells grafted to the denervated rat striatum. Neuron 5:393-402; 1990.
-
(1990)
Neuron
, vol.5
, pp. 393-402
-
-
Horellou, P.1
Brundin, P.2
Kalen, P.3
Mallet, J.4
Björklund, A.5
-
17
-
-
0028169741
-
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain
-
Kaplitt, M. G.; Leone, P.; Samulski, R. J.; Xiao, X.; Pfaff, D. W.; O'Malley, K. L.; During, M. J. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat. Genet. 8:148-154; 1994.
-
(1994)
Nat. Genet.
, vol.8
, pp. 148-154
-
-
Kaplitt, M.G.1
Leone, P.2
Samulski, R.J.3
Xiao, X.4
Pfaff, D.W.5
O'Malley, K.L.6
During, M.J.7
-
18
-
-
0023874410
-
Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications
-
Kish, S. J.; Shannak, K.; Hornykiewicz, O. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. N. Engl. J. Med. 318:876-880; 1988.
-
(1988)
N. Engl. J. Med.
, vol.318
, pp. 876-880
-
-
Kish, S.J.1
Shannak, K.2
Hornykiewicz, O.3
-
19
-
-
0032909852
-
Multipotent stem/progenitor cells with similar properties arise from two neurogenic regions of adult human brain
-
Kukekov, V. G.; Laywell, E. D.; Suslov, O.; Davies, K.; Scheffler, B.; Thomas, L. B.; O'Brien, T. F.; Kusakabe, M.; Steindler, D. A. Multipotent stem/progenitor cells with similar properties arise from two neurogenic regions of adult human brain. Exp. Neurol. 156:333-344; 1999.
-
(1999)
Exp. Neurol.
, vol.156
, pp. 333-344
-
-
Kukekov, V.G.1
Laywell, E.D.2
Suslov, O.3
Davies, K.4
Scheffler, B.5
Thomas, L.B.6
O'Brien, T.F.7
Kusakabe, M.8
Steindler, D.A.9
-
20
-
-
0032102936
-
In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via coexpression of GTP cyclohydrolasel with tyrosine hydroxylase
-
Leff, S. E.; Rendahl, K. G.; Spratt, S. K.; Kang, U. J.; Mandel, R. J. In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via coexpression of GTP cyclohydrolasel with tyrosine hydroxylase. Exp. Neurol. 151:249-264; 1998.
-
(1998)
Exp. Neurol.
, vol.151
, pp. 249-264
-
-
Leff, S.E.1
Rendahl, K.G.2
Spratt, S.K.3
Kang, U.J.4
Mandel, R.J.5
-
21
-
-
0042078783
-
Tetrahydrobiopterin in striatum: Localization in dopamine nerve terminals and role in catecholamine synthesis
-
Levine, R. A.; Miller, L. P.; Lovenberg, W. Tetrahydrobiopterin in striatum: Localization in dopamine nerve terminals and role in catecholamine synthesis. Science 213:349-350; 1981.
-
(1981)
Science
, vol.213
, pp. 349-350
-
-
Levine, R.A.1
Miller, L.P.2
Lovenberg, W.3
-
22
-
-
0025058215
-
Grafts of fetal dopamine neurons survive and improve motor function in Parkinso's disease
-
Lindvall, O.; Brundin, P.; Widner, H.; Rehncrona, S.; Gustavil, B.; Leenders, K.; Sawle, G.; Rothwell, J.; Marsden, C. Grafts of fetal dopamine neurons survive and improve motor function in Parkinso's disease. Science 247:574-577; 1990.
-
(1990)
Science
, vol.247
, pp. 574-577
-
-
Lindvall, O.1
Brundin, P.2
Widner, H.3
Rehncrona, S.4
Gustavil, B.5
Leenders, K.6
Sawle, G.7
Rothwell, J.8
Marsden, C.9
-
23
-
-
0032818773
-
Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus
-
Liu, Y.; Himes, B. T.; Solowska, J.; Chow, S. Y.; Park, K. I.; Tessler, A.; Murray, M.; Snyder, E. Y.; Fischer, I. Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus. Exp. Neurol. 158:9-26; 1999.
-
(1999)
Exp. Neurol.
, vol.158
, pp. 9-26
-
-
Liu, Y.1
Himes, B.T.2
Solowska, J.3
Chow, S.Y.4
Park, K.I.5
Tessler, A.6
Murray, M.7
Snyder, E.Y.8
Fischer, I.9
-
24
-
-
0036884733
-
Pathogenesis of Parkinson's disease: Dopamine, vesicles and alpha-synuclein
-
Lotharius, J.; Brundin, P. Pathogenesis of Parkinson's disease: Dopamine, vesicles and alpha-synuclein. Nat. Rev. Neurosci. 3:932-942; 2002.
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 932-942
-
-
Lotharius, J.1
Brundin, P.2
-
25
-
-
0029973056
-
Generation of DOPA-producing astrocytes by retroviral transduction of the human tyrosine hydroxylase gene: In vitro and in vivo effects in the rat parkinson model
-
Lundberg, C.; Horellou, P.; Mallet, J.; Björklund, A. Generation of DOPA-producing astrocytes by retroviral transduction of the human tyrosine hydroxylase gene: In vitro and in vivo effects in the rat parkinson model. Exp. Neurol. 139:39-53; 1996.
-
(1996)
Exp. Neurol.
, vol.139
, pp. 39-53
-
-
Lundberg, C.1
Horellou, P.2
Mallet, J.3
Björklund, A.4
-
26
-
-
0030838238
-
Immortalized neural progenitor cells for CNS gene transfer and repair
-
Martinez-Serrano, A.; Björklund, A. Immortalized neural progenitor cells for CNS gene transfer and repair. Trends Neurosci. 20:530-538; 1997.
-
(1997)
Trends Neurosci.
, vol.20
, pp. 530-538
-
-
Martinez-Serrano, A.1
Björklund, A.2
-
27
-
-
0030894092
-
Stem cell in the nervous system
-
Mckay, R. Stem cell in the nervous system. Science 276:66-71; 1997.
-
(1997)
Science
, vol.276
, pp. 66-71
-
-
Mckay, R.1
-
28
-
-
0027243120
-
Use of retroviral vectors for gene transfer and expression
-
Miller, A. D.; Miller, D. G.; Garcia, J. V.; Lynch, C. M. Use of retroviral vectors for gene transfer and expression. Methods Enzymol. 217:581-599; 1993.
-
(1993)
Methods Enzymol.
, vol.217
, pp. 581-599
-
-
Miller, A.D.1
Miller, D.G.2
Garcia, J.V.3
Lynch, C.M.4
-
29
-
-
0025352187
-
Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
-
Morgenstern, J. P.; Land, H. Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 18:3587-3596; 1990.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 3587-3596
-
-
Morgenstern, J.P.1
Land, H.2
-
30
-
-
0020563575
-
Biopterin cofactor and monoamine-synthesizing monooxygenases
-
Nagatsu, T. Biopterin cofactor and monoamine-synthesizing monooxygenases. Neurochem. Int. 5:27-38; 1983.
-
(1983)
Neurochem. Int.
, vol.5
, pp. 27-38
-
-
Nagatsu, T.1
-
32
-
-
0021891891
-
Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin
-
Nichol, C. A.; Smith, G. K.; Duch, D. S. Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin. Annu. Rev. Biochem. 54:729-764; 1985.
-
(1985)
Annu. Rev. Biochem.
, vol.54
, pp. 729-764
-
-
Nichol, C.A.1
Smith, G.K.2
Duch, D.S.3
-
33
-
-
0030041034
-
Fetal nigral transplantation as a therapy for Parkinsons disease
-
Olanow, C. W.; Kordower, J.; Freeman, T. Fetal nigral transplantation as a therapy for Parkinsons disease. Trends Neurosci. 19:102-109; 1996.
-
(1996)
Trends Neurosci.
, vol.19
, pp. 102-109
-
-
Olanow, C.W.1
Kordower, J.2
Freeman, T.3
-
34
-
-
0026073781
-
Dihydroxyphenylalanine synthesis by genetically modified Schwann cells
-
Owens, G. C.; Johnson, R.; Bunge, R. P.; O'Malley, K. L. Dihydroxyphenylalanine synthesis by genetically modified Schwann cells. J. Neurochem. 56:-1030-1036; 1991.
-
(1991)
J. Neurochem.
, vol.56
, pp. 1030-1036
-
-
Owens, G.C.1
Johnson, R.2
Bunge, R.P.3
O'Malley, K.L.4
-
36
-
-
0031105522
-
Application of ex vivo gene therapy in the treatment of Parkinson's disease
-
Raymon, H. K.; Thode, S.; Gage, F. H. Application of ex vivo gene therapy in the treatment of Parkinson's disease. Exp. Neurol. 144:82-91; 1997.
-
(1997)
Exp. Neurol.
, vol.144
, pp. 82-91
-
-
Raymon, H.K.1
Thode, S.2
Gage, F.H.3
-
37
-
-
0030668245
-
Differentiation of engrafted multipotent neural progenitors towards replacement of missing granule neurons in meander tail cerebellum may help determine the locus of mutant gene action
-
Rosario, C. M.; Yandava, B. D.; Kosaras, B.; Zurakowski, D.; Sidman, R. L.; Snyder, E. Y. Differentiation of engrafted multipotent neural progenitors towards replacement of missing granule neurons in meander tail cerebellum may help determine the locus of mutant gene action. Development 124:4213-4224; 1997.
-
(1997)
Development
, vol.124
, pp. 4213-4224
-
-
Rosario, C.M.1
Yandava, B.D.2
Kosaras, B.3
Zurakowski, D.4
Sidman, R.L.5
Snyder, E.Y.6
-
38
-
-
0025237864
-
Establishment and characterization of multipotent neural cell lines using retrovirus vector-mediated oncogene transfer
-
Ryder, E. F.; Snyder, E. Y.; Cepko, C. L. Establishment and characterization of multipotent neural cell lines using retrovirus vector-mediated oncogene transfer. J. Neurobiol. 21:356-375; 1990.
-
(1990)
J. Neurobiol.
, vol.21
, pp. 356-375
-
-
Ryder, E.F.1
Snyder, E.Y.2
Cepko, C.L.3
-
39
-
-
0026501444
-
Multipotent neural cell lines can engraft and participate in development of mouse cerebellum
-
Snyder, E. Y.; Deitcher, D. L.; Walsh, C.; Arnold-Aldea, S.; Hartwieg, E. A.; Cepko, C. L. Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell 68:33-51; 1992.
-
(1992)
Cell
, vol.68
, pp. 33-51
-
-
Snyder, E.Y.1
Deitcher, D.L.2
Walsh, C.3
Arnold-Aldea, S.4
Hartwieg, E.A.5
Cepko, C.L.6
-
40
-
-
0033536064
-
"Global" cell replacement is feasible via neural stem cell transplantation: Evidence from the dysmyelinated shiverer mouse brain
-
Yandava, B. D.; Billinghurst, L.; Snyder, E. Y. "Global" cell replacement is feasible via neural stem cell transplantation: Evidence from the dysmyelinated shiverer mouse brain. Proc. Natl. Acad. Sci. USA 96:7029-7034; 1999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7029-7034
-
-
Yandava, B.D.1
Billinghurst, L.2
Snyder, E.Y.3
|