CDK inhibitor p18INK4c is required for the generation of functional plasma cells

Immunity

Volumn 17, Issue 2, 2002, Pages 179-189

  Tourigny, Michelle R ^a   Ursini Siegel, Josie ^a   Lee, Hayyoung ^a   Toellner, Kai Michael ^b   Cunningham, Adam F ^b   Franklin, David S ^c   Ely, Scott ^a   Chen, Meihong ^a   Qin, Xiao Feng ^d   Xiong, Yue ^e   MacLennan, Ian C M ^b   Chen Kiang, Selina ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

^c PURDUE UNIVERSITY   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; LYMPHOCYTE ANTIBODY; T LYMPHOCYTE ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL CYCLE; CONTROLLED STUDY; GENE MUTATION; GENETIC RECOMBINATION; LYMPH FOLLICLE; LYMPHOCYTE PROLIFERATION; MITOSIS INHIBITION; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; REGULATORY MECHANISM;

EID: 18644374059     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(02)00364-3     Document Type: Article

References (42)

1. Ahmed R., Gray D. Immunological memory and protective immunity. understanding their relation Science. 272:1996;54-60.
2. Calfon M., Zeng H., Urano F., Till J.H., Hubbard S.R., Harding H.P., Clark S.G., Ron D. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature. 415:2002;92-96.
3. Chan F.K., Zhang J., Cheng L., Shapiro D.N., Winoto A. Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4. Mol. Cell. Biol. 15:1995;2682-2688.
4. Chang D.H., Angelin-Duclos C., Calame K. BLIMP-1. trigger for differentiation of myeloid lineage Nat. Immunol. 1:2000;169-176.
5. Cumano A., Rajewsky K. Structure of primary anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in normal and idiotypically suppressed C57BL/6 mice. Eur. J. Immunol. 15:1985;512-520.
6. Do R.K.G., Hatada E., Lee H., Tourigny M.R., Hilbert D., Chen-Kiang S. Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response. J. Exp. Med. 192:2000;953-964.
7. Franklin D.S., Xiong Y. Induction of p18INK4C and its predominant association with CDK4 and CDK6 during myogenic differentiation. Mol. Biol. Cell. 7:1996;1587-1599.
8. Franklin D.S., Godfrey V.L., Lee H., Kovalev G.I., Schoonhoven R., Chen-Kiang S., Su L., Xiong Y. CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis. Genes Dev. 12:1998;2899-2911.
9. INK4B/MTS2-related CDK inhibitor, correlates with wild-type pRb function. Genes Dev. 8:1994;2939-2952.
10. Guan K.L., Jenkins C.W., Li Y., O'Keefe C.L., Noh S., Wu X., Zariwal A.G., Xiong Y. Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4. Mol. Biol. Cell. 7:1996;57-70.
11. Haas I.G., Wabl M. Immunoglobulin heavy chain binding protein. Nature. 306:1983;387-389.
12. Hirai H., Roussel M.F., Kato J.Y., Ashmun R.A., Sherr C.J. Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. Mol. Cell. Biol. 15:1995;2672-2681.
13. Hunter T., Pines J. Cyclins and Cancer II. cyclin D and Cdk inhibitors come of age Cell. 79:1994;573-582.
14. Jacob J., Kassir R., Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. J. Exp. Med. 173:1991;1165-1175.
15. Jacob J., Przylepa J., Miller C., Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells. J. Exp. Med. 178:1993;1293-1307.
16. Kabat E., Wu T.T., Perry H.M., Gottesman K.S., Foeller C. Sequences of Proteins of Immunological Interest. Number 91-3242. 1991;National Institutes of Health Publications, Bethesda, MD.
17. Kopf M., Baumann H., Freer G., Freudenberg M., Lamers M., Kishimoto T., Zinkernagel R., Bluethmann H., Kohler G. Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature. 368:1994;339-342.
18. Kovalev G.I., Franklin D.S., Coffield V.M., Xiong Y., Su L. An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation. J. Immunol. 167:2001;3285-3292.
19. Lam E.W., Glassford J., Banerji L., Thomas N.S., Sicinski P., Klaus G.G. Cyclin D3 compensates for loss of cyclin D2 in mouse B-lymphocytes activated via the antigen receptor and CD40. J. Biol. Chem. 275:2000;3479-3484.
20. Latres E., Malumbres M., Sotillo R., Martin J., Ortega S., Martin-Caballero J., Flores J.M., Cordon-Cardo C., Barbacid M. Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis. EMBO J. 19:2000;3496-3506.
21. Lee A.S. The glucose-regulated proteins. stress induction and clinical applications Trends Biochem. Sci. 26:2001;504-510.
22. Lee A.S., Delegeane A., Scharff D. Highly conserved glucose-regulated protein in hamster and chicken cells. preliminary characterization of its cDNA clone Proc. Natl. Acad. Sci. USA. 78:1981;4922-4925.
23. Liou H.C., Boothby M.R., Finn P.W., Davidon R., Nabavi N., Zeleznik-Le N.J., Ting J.P., Glimcher L.H. A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter. Science. 247:1990;1581-1584.
24. Liu Y.J., Zhang J., Lane P.J., Chan E.Y., MacLennan I.C. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur. J. Immunol. 21:1991;2951-2962.
25. Luther S.A., Gulbranson-Judge A., Acha-Orbea H., MacLennan I.C. Viral superantigen drives extrafollicular and follicular B cell differentiation leading to virus-specific antibody production. J. Exp. Med. 185:1997;551-562.
26. Melnick J., Dul J.L., Argon Y. Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum. Nature. 370:1994;373-375.
27. INK4C and IL-6. Immunity. 6:1997;47-56.
28. Piskurich J.F., Lin K.I., Lin Y., Wang Y., Ting J.P., Calame K. BLIMP-I mediates extinction of major histocompatibility class II transactivator expression in plasma cells. Nat. Immunol. 1:2000;526-532.
29. Ramsay A.J., Husband A.J., Ramshaw I.A., Bao S., Matthaei K.I., Koehler G., Kopf M. The role of interleukin-6 in mucosal IgA antibody responses in vivo. Science. 264:1994;561-563.
30. Reimold A.M., Iwakoshi N.N., Manis J., Vallabhajosyula P., Szomolanyi-Tsuda E., Gravallese E.M., Friend D., Grusby M.J., Alt F., Glimcher L.H. Plasma cell differentiation requires the transcription factor XBP-1. Nature. 412:2001;300-307.
31. Sherr C., Roberts J.M. CDK inhibitors. positive and negative regulation of G1-phase progression Genes Dev. 13:1999;1501-1512.
32. Smith K.G., Light A., Nossal G.J., Tarlinton D.M. The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response. EMBO J. 16:1997;2996-3006.
33. Solvason N., Wu W.W., Kabra N., Wu X., Lees E., Howard M.C. Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes. J. Exp. Med. 184:1996;407-417.
34. Starborg M., Gell K., Brundell E., Hoog C. The murine Ki-67 cell proliferation antigen accumulates in the nucleolar and heterochromatic regions of interphase cells and at the periphery of the mitotic chromosomes in a process essential for cell cycle progression. J. Cell Sci. 109:1996;143-153.
35. Stuber E., Neurath M., Calderhead D., Fell H.P., Strober W. Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Immunity. 2:1995;507-521.
36. Sze D.M., Toellner K.M., Garcia de Vinuesa C., Taylor D.R., MacLennan I.C. Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival. J. Exp. Med. 192:2000;813-821.
37. Tanguay D.A., Chiles T.C. Regulation of the catalytic subunit (p34PSK-J3Cdk4) for the major D-type cyclin in mature B cells. J. Immunol. 156:1996;539-548.
38. Toellner K.M., Gulbranson-Judge A., Taylor D.R., Sze D.M., MacLennan I.C. Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation. J. Exp. Med. 183:1996;2303-2312.
39. Turner C.A. Jr., Mack D.H., Davis M.M. Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. Cell. 77:1994;297-306.
40. Weinberg R.A. The retinoblastoma protein and cell cycle control. Cell. 81:1995;323-330.
41. Weiss U., Zoebelein R., Rajewsky K. Accumulation of somatic mutants in the B cell compartment after primary immunization with a T cell-dependent antigen. Eur. J. Immunol. 22:1992;511-517.
42. Yoshida H., Matsui T., Yamamoto A., Okada T., Mori K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell. 107:2001;881-891.