메뉴 건너뛰기




Volumn 7, Issue 6, 1996, Pages 385-388

Statins: Within-group comparisons, statin escape and combination therapy

Author keywords

[No Author keywords available]

Indexed keywords

ANTILIPEMIC AGENT; BEZAFIBRATE; FIBRIC ACID DERIVATIVE; FLUINDOSTATIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; PRAVASTATIN; SIMVASTATIN;

EID: 0030504865     PISSN: 09579672     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041433-199612000-00008     Document Type: Short Survey
Times cited : (29)

References (28)
  • 1
    • 0029927738 scopus 로고    scopus 로고
    • Heart attacks: Gone with the century?
    • Brown MS, Goldstein JL: Heart attacks: gone with the century? Science 1996, 272:629. A view from the vantage point.
    • (1996) Science , vol.272 , pp. 629
    • Brown, M.S.1    Goldstein, J.L.2
  • 2
    • 0028245981 scopus 로고
    • Defined daily doses in relation to hypolipidaemic efficacy of lovastatin, pravastatin, and simvastatin
    • Illingworth DR, Erkelens DW, Keller U, Thompson GR, Tikkanen MJ: Defined daily doses in relation to hypolipidaemic efficacy of lovastatin, pravastatin, and simvastatin. Lancet 1994, 343:1554-1555.
    • (1994) Lancet , vol.343 , pp. 1554-1555
    • Illingworth, D.R.1    Erkelens, D.W.2    Keller, U.3    Thompson, G.R.4    Tikkanen, M.J.5
  • 4
    • 0029151077 scopus 로고
    • Double-blind comparison of the efficacy and tolerability of simvastatin and fluvastatin in patients with primary hypercholesterolaemia
    • Ose L, Scott R, the Simvastatin-Fluvastatin Study Group: Double-blind comparison of the efficacy and tolerability of simvastatin and fluvastatin in patients with primary hypercholesterolaemia. Clin Drug Invest 1995, 10:127-138. Two studies indicating that simvastatin is approximately seven times as effective as fluvastatin in lowering LDL-cholesterol.
    • (1995) Clin Drug Invest , vol.10 , pp. 127-138
    • Ose, L.1    Scott, R.2
  • 5
    • 0029899142 scopus 로고    scopus 로고
    • Simvastatin-fluvastatin comparative study
    • Deslypere JP: Simvastatin-fluvastatin comparative study. Clin Drug Invest 1996, 11:362-363.
    • (1996) Clin Drug Invest , vol.11 , pp. 362-363
    • Deslypere, J.P.1
  • 6
    • 0029025022 scopus 로고
    • Comparison of fluvastatin versus pravastatin treatment of primary hypercholesterolemia
    • Jacotot B, Benghozi R, Pfister P, Holmes D: Comparison of fluvastatin versus pravastatin treatment of primary hypercholesterolemia. Am J Cardiol 1995, 76:54A-56A.
    • (1995) Am J Cardiol , vol.76
    • Jacotot, B.1    Benghozi, R.2    Pfister, P.3    Holmes, D.4
  • 8
    • 0023239681 scopus 로고
    • Long term administration of lovastatin in the treatment of hypercholesterolaemia
    • Illingworth DR: Long term administration of lovastatin in the treatment of hypercholesterolaemia. Eur Heart J 1987, 8E: 103-111.
    • (1987) Eur Heart J , vol.8 E , pp. 103-111
    • Illingworth, D.R.1
  • 9
    • 0029019470 scopus 로고
    • Escape phenomenon of low-density lipoprotein cholesterol during lovastatin treatment
    • Rubinstein A, Weintraub M: Escape phenomenon of low-density lipoprotein cholesterol during lovastatin treatment. Am J Cardiol 1995, 76:184-186. A study focusing on a subgroup (n = 26) of 233 patients receiving lovastatin 20 mg per day whose LDL-cholesterol levels increased by more than 10% during ongoing treatment. The authors considered impaired patient compliance, compensatory induction of HMG CoA reductase activity and induction of the statin-metabolizing cytochrome P-450 3A enzymes as possible explanations of this 'statin escape' phenomenon.
    • (1995) Am J Cardiol , vol.76 , pp. 184-186
    • Rubinstein, A.1    Weintraub, M.2
  • 10
    • 0017894322 scopus 로고
    • Induction of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase
    • Brown MS, Faust JR, Goldstein JL, Kaneko I, Endo A: Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase. J Biol Chem 1978, 253:1121-1128.
    • (1978) J Biol Chem , vol.253 , pp. 1121-1128
    • Brown, M.S.1    Faust, J.R.2    Goldstein, J.L.3    Kaneko, I.4    Endo, A.5
  • 11
    • 0027215237 scopus 로고
    • Time response of cholesterol synthesis inhibition by compactin-related compounds. in vitro quantitation of the 'escape phenomenon'
    • Sviridov DD, Endo A, Pavlov MY, Repin VS: Time response of cholesterol synthesis inhibition by compactin-related compounds. In vitro quantitation of the 'escape phenomenon'. Lipids 1993, 28:569-571.
    • (1993) Lipids , vol.28 , pp. 569-571
    • Sviridov, D.D.1    Endo, A.2    Pavlov, M.Y.3    Repin, V.S.4
  • 12
    • 0025944905 scopus 로고
    • Biotransformation of lovastatin. Identification of cytochrome P-450-3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes
    • Wang RW, Kami PH, Lu AY, Thomas PE, Guengerich FP, Vyas MP. Biotransformation of lovastatin. Identification of cytochrome P-450-3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes Arch Biochem Biophys 1991, 290:355-361.
    • (1991) Arch Biochem Biophys , vol.290 , pp. 355-361
    • Wang, R.W.1    Kami, P.H.2    Lu, A.Y.3    Thomas, P.E.4    Guengerich, F.P.5    Vyas, M.P.6
  • 13
    • 0025292999 scopus 로고
    • Long-term maintenance of therapeutic response to lovastatin in patients with familial and non-familial hypercholesterolemia: A 3-year follow-up
    • Ojala J-P, Helve E, Karjalainen K, Tarkkanen A, Tikkanen MJ: Long-term maintenance of therapeutic response to lovastatin in patients with familial and non-familial hypercholesterolemia: a 3-year follow-up. Atherosclerosis 1990; 82:85-95.
    • (1990) Atherosclerosis , vol.82 , pp. 85-95
    • Ojala, J.-P.1    Helve, E.2    Karjalainen, K.3    Tarkkanen, A.4    Tikkanen, M.J.5
  • 16
    • 0029025021 scopus 로고
    • Long-term efficacy with fluvastatin as monotherapy and combined with cholestyramine (A 156-Week Multicenter Study)
    • Jacotot B, Banga JD, Waite R, Peters TK: Long-term efficacy with fluvastatin as monotherapy and combined with cholestyramine (A 156-Week Multicenter Study) Am J Cardiol 1995, 76:41A-46A.
    • (1995) Am J Cardiol , vol.76
    • Jacotot, B.1    Banga, J.D.2    Waite, R.3    Peters, T.K.4
  • 18
    • 0025365041 scopus 로고
    • Myopathy and rhabdomyosis associated with lovastatin-gemfibrozil combination therapy
    • Pierce LR, Wysowski DK, Gross TP: Myopathy and rhabdomyosis associated with lovastatin-gemfibrozil combination therapy. JAMA 1990, 264:71-75.
    • (1990) JAMA , vol.264 , pp. 71-75
    • Pierce, L.R.1    Wysowski, D.K.2    Gross, T.P.3
  • 19
    • 0026600799 scopus 로고
    • Fibric acid derivatives
    • Tikkanen MJ: Fibric acid derivatives. Curr Opin Lipidol 1992, 3:29-33.
    • (1992) Curr Opin Lipidol , vol.3 , pp. 29-33
    • Tikkanen, M.J.1
  • 20
    • 0029033081 scopus 로고
    • Long-term safety of statin-fibrate combination treatment in the management of hypercholesterolemia in patients with coronary artery disease
    • Feher MD, Foxton J, Banks D, Lant AF, Wray R: Long-term safety of statin-fibrate combination treatment in the management of hypercholesterolemia in patients with coronary artery disease. Br Heart J 1995, 74:14-17. A long-term study of 102 patients, most of whom received bezafibrate 400 mg per day plus simvastatin 10-20 mg per day, did not reveal any occurrence of myalgia or marked elevations of creatine phosphokinase activity. The 'myopathy syndrome' has reportedly been associated with the combined use of statins and fibrates.
    • (1995) Br Heart J , vol.74 , pp. 14-17
    • Feher, M.D.1    Foxton, J.2    Banks, D.3    Lant, A.F.4    Wray, R.5
  • 21
    • 0029003602 scopus 로고
    • Treatment of combined hyperlipidemia with fluvastatin and gemfibrozil, alone or in combination, does not induce muscle damage
    • Smit JWA, Jansen GH, de Bruin TWA, Erkelens DW: Treatment of combined hyperlipidemia with fluvastatin and gemfibrozil, alone or in combination, does not induce muscle damage. J Cardiol 1995, 76:126A-128A.
    • (1995) J Cardiol , vol.76
    • Smit, J.W.A.1    Jansen, G.H.2    De Bruin, T.W.A.3    Erkelens, D.W.4
  • 22
    • 0029591846 scopus 로고
    • Selection of appropriate type and intensity of lipid lowering therapy
    • Tikkanen MJ: Selection of appropriate type and intensity of lipid lowering therapy. Curr Opin Lipidol 1995, 6:360-364.
    • (1995) Curr Opin Lipidol , vol.6 , pp. 360-364
    • Tikkanen, M.J.1
  • 23
    • 0030012771 scopus 로고    scopus 로고
    • The effect of simvastatin treatment on the concentrations of antioxidant vitamins in low density lipoproteins and high-energy phosphates and ubiquinone in skeletal muscle
    • Laaksonen R, Jokelainen K, Laakso J, Sahi T, Härkönen M, Tikkanen MJ, Himberg J-J: The effect of simvastatin treatment on the concentrations of antioxidant vitamins in low density lipoproteins and high-energy phosphates and ubiquinone in skeletal muscle. Am J Cardiol 1996, 77:851-854.
    • (1996) Am J Cardiol , vol.77 , pp. 851-854
    • Laaksonen, R.1    Jokelainen, K.2    Laakso, J.3    Sahi, T.4    Härkönen, M.5    Tikkanen, M.J.6    Himberg, J.-J.7
  • 24
    • 0028037215 scopus 로고
    • Dual bezafibrate-simvastatin therapy for combined hyperlipidaemia
    • Hutchesson ACJ, Moran A, Jones AF: Dual bezafibrate-simvastatin therapy for combined hyperlipidaemia. J Clin Pharmacy 1994, 19:387-389.
    • (1994) J Clin Pharmacy , vol.19 , pp. 387-389
    • Hutchesson, A.C.J.1    Moran, A.2    Jones, A.F.3
  • 25
    • 0029053683 scopus 로고
    • High-dose fluvastatin and bezafibrate combination treatment for heterozygous familial hypercholesterolemia
    • Eliav O, Schurr D, Pfister R Friedlander Y, Leitersdorf E: High-dose fluvastatin and bezafibrate combination treatment for heterozygous familial hypercholesterolemia. Am J Cardiol 1995, 76:76A-79A.
    • (1995) Am J Cardiol , vol.76
    • Eliav, O.1    Schurr, D.2    Pfister, R.3    Friedlander, Y.4    Leitersdorf, E.5
  • 26
    • 0029065668 scopus 로고
    • Efficacy and safety of triple therapy (fluvastatin-bezafibrate-cholestyramine) for severe familial hypercholesterolemia
    • Leitersdorf E, Muratti EN, Eliav O, Peters TK: Efficacy and safety of triple therapy (fluvastatin-bezafibrate-cholestyramine) for severe familial hypercholesterolemia. Am J Cardiol 1995, 76:84A-88A.
    • (1995) Am J Cardiol , vol.76
    • Leitersdorf, E.1    Muratti, E.N.2    Eliav, O.3    Peters, T.K.4
  • 27
    • 9044230921 scopus 로고    scopus 로고
    • Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia
    • Bakker-Arkema RG, Davidson MH, Goldstein RJ, Davignon J, Isaacsohn J, Weiss SR, Keilson LM, Brown WV, Miller VT, Shurzinske LJ, Black DM: Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia JAMA 1996, 275:128-133. Atorvastatin, a novel member of the statin family, was shown to reduce not only LDL-cholesterol but also plasma triglyceride levels in a dose-dependent manner in hypertriglyceridemic patients.
    • (1996) JAMA , vol.275 , pp. 128-133
    • Bakker-Arkema, R.G.1    Davidson, M.H.2    Goldstein, R.J.3    Davignon, J.4    Isaacsohn, J.5    Weiss, S.R.6    Keilson, L.M.7    Brown, W.V.8    Miller, V.T.9    Shurzinske, L.J.10    Black, D.M.11
  • 28
    • 0029982038 scopus 로고    scopus 로고
    • Angiographic assessment of effects of bezafibrate on progression of coronary artery disease in young male postinfarction patients
    • Ericsson C-G, Hamster A, Nilsson J, Grip L, Svane B, de Faire U: Angiographic assessment of effects of bezafibrate on progression of coronary artery disease in young male postinfarction patients. Lancet 1996, 347:849-853. This angiographic study was the first designed to assess the effects of a fibrate on progression of coronary atherosclerosis in men who had suffered a myocardial infarction. Eighty-one patients completed the 5 year study receiving either placebo or bezafibrate 200 mg three times daily. Bezafibrate was shown to slow the progression of atherosclerosis and to reduce clinical events despite the fact that LDL-cholesterol levels remained stable.
    • (1996) Lancet , vol.347 , pp. 849-853
    • Ericsson, C.-G.1    Hamster, A.2    Nilsson, J.3    Grip, L.4    Svane, B.5    De Faire, U.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.