Compensatory elevation of complex II activity in Leber's hereditary optic neuropathy

British Journal of Ophthalmology

Volumn 80, Issue 1, 1996, Pages 78-81

  Yen, May Yung ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; MITOCHONDRIAL ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE;

ADOLESCENT; ADULT; ARTICLE; BLOOD CELL; CLINICAL ARTICLE; ENZYME ACTIVITY; FEMALE; HEREDITARY OPTIC ATROPHY; HUMAN; MALE; MITOCHONDRIAL RESPIRATION; POINT MUTATION; PRIORITY JOURNAL;

EID: 0030053091     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.80.1.78     Document Type: Article

References (5)

1. Wallace DC, Singh G, Lett MT, Hodge JA, Schurr TG, Lezza AMS, et a!. Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. Science 1988; 242: 1427-30.
2. Huoponen K, Vilkki J, Aila P, Nikoskelainen EK, Savontaus ML. A new mtDNA mutation associated with Leber hereditary optic neuropathy. Am J Hum Genet 1991; 48: 147-53.
3. Johns DR, Berman J. Alternative, simultaneous complex I mitochondrial DNA mutations in Leber's hereditary optic neuropathy. Biochem Biophys Res Commun 1991; 174: 1324-30.
4. Brown MD, Voljavec AS, Lott MT, Torrini A, Yang CC, Wallace DC. Mitochondrial DNA complex I and III mutations associated with Leber's hereditary optic neuropathy. Genetics 1992; 130: 163-73.
5. Howell N, Bindoff LA, McCullough DA, Kubacka I, Poulton J, Mackey D, et al. Leber hereditary optic neuropathy: identification of the same mitochondrial ND1 mutation in six pedigrees. Am J Hum Genet 1991; 49: 939-50.