Orientation changes of the myosin light chain domain during filament sliding in active and rigor muscle

Journal of Molecular Biology

Volumn 318, Issue 5, 2002, Pages 1275-1291

  Hopkins, Seth C ^a   Sabido David, Cibele ^b   Van Der Heide, Uulke A ^a   Ferguson, Roisean E ^c   Brandmeier, Birgit D ^c   Dale, Robert E ^b   Kendrick Jones, John ^d   Corrie, John E T ^c   Trentham, David R ^c   Irving, Malcolm ^b   Goldman, Yale E ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^d MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Bifunctional probe; Fluorescence polarization; Mechanical transients; Muscle; Myosin

Indexed keywords

ACTIN; MYOSIN LIGHT CHAIN; RHODAMINE;

ARTICLE; FLUORESCENCE; MOTION; MUSCLE CONTRACTION; MYOFILAMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN;

EID: 18444403111     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00189-4     Document Type: Article

References (72)

1. Induced changes in orientation of the cross-bridges of glycerinated insect flight muscle
2. Electron tomography of insect flight muscle in rigor and AMPPNP at 23°C
3. Structural changes in muscle crossbridges accompanying force generation
4. 2+-activated contracting insect flight muscle
5. Changes in the X-ray reflections from contracting muscle during rapid mechanical transients and their structural implications
6. Myosin head movements are synchronous with the elementary force-generating process in muscle
7. The mechanism of force generation by myosin heads in skeletal muscle
8. Three-dimensional structure of myosin sub-fragment-1: A molecular motor
9. Structure of the actin-myosin complex and its implications for muscle contraction
10. X-ray structure of the magnesium (II)·ADP·vanadate complex of the Dictyostelium discoideum myosin motor domain to 1.9 Å resolution
11. Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: Visualization of the pre-power stroke state
12. Atomic structure of scallop myosin subfragment S1 complexed with MgADP: A novel conformation of the myosin head
13. Three conformational states of scallop myosin S1
14. Tilting of the light-chain region of myosin during step length changes and active force generation in skeletal muscle
15. Fluorescence polarization transients from rhodamine isomers on the myosin regulatory light chain in skeletal musle fibers
16. A large and distinct rotation of the myosin light chain domain occurs upon muscle contraction
17. Dynamic measurement of myosin light-chain-domain tilt and twist in muscle contraction
18. Wag the tail: Structural dynamics of actomyosin
19. Structural mechanism of muscle contraction
20. The neck region of the myosin motor domain acts as a lever arm to generate movement
21. The light chain binding domain of expressed smooth muscle heavy meromyosin acts as a mechanical lever
22. An unexpectedly large working stroke from chymotryptic fragments of myosin II
23. Single-molecule tracking of myosins with genetically engineered amplifier domains
24. Myosin V exhibits a high duty cycle and large unitary displacement
25. Resolution of three structural states of spin-labeled myosin in contracting muscle
26. Muscle force is generated by myosin heads stereospecifically attached to actin
27. Structural changes in the actin-myosin cross-bridges associated with force generation induced by temperature jump in perme-abilized frog muscle fibers
28. Elastic distortion of myosin heads and repriming of the working stroke in muscle
29. Elastic bending and active tilting of myosin heads during muscle contraction
30. Conformation of the myosin motor during force generation in skeletal muscle
31. Orientation changes of fluorescent probes at five sites on the myosin regulatory light chain during contraction of single skeletal muscle fibres
32. Fluorescence polarization of skeletal muscle fibers labeled with rhodamine isomers on the myosin heavy chain
33. Probes bound to myosin Cys-707 rotate during length transients in contraction
34. A homobifunctional rhodamine for labeling proteins with defined orientations of a fluorophore
35. A maximum entropy analysis of protein orientations using fluorescence polarization data from multiple probes
36. Fluorescent probes of the orientation of myosin regulatory light chains in relaxed, rigor, and contracting muscle
37. Steady-state fluorescence polarization studies of the orientation of myosin regulatory light chains in single skeletal muscle fibers using pure isomers of iodoacetamidotetramethylrhodamine
38. Model-independent analysis of the orientation of fluorescent probes with restricted mobility in muscle fibers
39. Proposed mechanism of force generation in striated muscle
40. All myosin heads form bonds with actin in rigor rabbit skeletal muscle
41. Orientation of spin-labeled myosin heads in glycerinated muscle fibers
42. Fraction of myosin heads bound to thin filaments in rigor fibrils from insect flight and vertebrate muscles
43. X-ray diffraction measurements of the extensibility of actin and myosin filaments in contracting muscle
44. X-ray diffraction evidence for the extensibility of actin and myosin filaments during muscle contraction
45. Compliance of thin filaments in skinned fibers of rabbit skeletal muscle
46. Evidence for cleft closure in actomyosin upon ADP release
47. Effects of AMPPNP on the orientation and rotational dynamics of spin-labeled muscle cross-bridges
48. Energetics of the actomyosin bond in the filament array of muscle fibers
49. 2+-regulated myosin
50. Dynamic behaviour of the head-tail junction of myosin
51. Electron tomography of insect flight muscle in rigor and AMPPNP at 23°C
52. Coiled-coil unwinding at the smooth muscle myosin head-rod junction is required for optimal mechanical performance
53. Stress does not alter the conformation of a domain of the myosin cross-bridge in rigor muscle fibres
54. Image reconstruction using electron micrographs of insect flight muscle
55. Structural change of crossbridges of rabbit skeletal muscle during isometric contraction
56. Flash and smash: Rapid freezing of muscle fibers activated by photolysis of caged ATP
57. Active and rigor stiffness in skinned fibers of rabbit psoas muscle
58. The stiffness of skeletal muscle in isometric contraction and rigor: The fraction of myosin heads bound to actin
59. Effect of joule temperature jump on tension and stiffness of skinned rabbit muscle fibers
60. 2+
61. Cross-bridge detachment and attachment following a step stretch imposed on active single frog muscle fibres
62. Rapid cross-bridge recruitment during stretch of active single fibers of frog skeletal muscle
63. Mechanochemical coupling in spin-labeled, active, isometric muscle
64. Orientation changes in myosin regulatory light chains following photorelease of ATP in skinned muscle fibers
65. Effects of pH on contraction of rabbit fast and slow skeletal muscle fibers
66. Force generation and work production by covalently cross-linked actin-myosin cross-bridges in rabbit muscle fibers
67. The contractile response during steady lengthening of stimulated frog muscle fibres
68. Control of sarcomere length in skinned muscle fibres of Rana temporaria during mechanical transients
69. Measurement of sarcomere shortening in skinned fibers from frog muscle by white light diffraction
70. Transients in orientation of a fluorescent cross-bridge probe following photolysis of caged nucleotides in skeletal muscle fibres
71. Smoothing and differentiation of data by simplified least squares procedures