Coiled-coil unwinding at the smooth muscle myosin head-rod junction is required for optimal mechanical performance

Biophysical Journal

Volumn 80, Issue 4, 2001, Pages 1900-1904

  Lauzon, Anne Marie ^a   Fagnant, Patty M ^b   Warshaw, David M ^b   Trybus, Kathleen M ^b  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF VERMONT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; LEUCINE ZIPPER PROTEIN; MEROMYOSIN; MYOSIN;

ANIMAL CELL; ARTICLE; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; SMOOTH MUSCLE;

ANIMALIA;

EID: 0035066654     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)76159-0     Document Type: Article

References (6)

1. 2+-regulated myosin. J. Mol. Biol. 140:35-55.
2. Cremo, C. R., J. R. Sellers, and K. C. Facemyer. 1995. Two heads are required for phosphorylation-dependent regulation of smooth muscle myosin. J. Biol. Chem. 270:2171-2175.
3. Dupuis, D. E., W. H. Guilford, J. Wu, and D. M. Warshaw. 1997. Actin filament mechanics in the laser trap. J Muscle Res. Cell Motil. 18:17-30.
4. Finer, J. F., R. M. Simmons, and J. A. Spudich. 1994. Single myosin molecule mechanics: piconewton forces and nanometer steps. Nature. 368:113-119.
5. Frank, S., A. Lustig, T. Schulthess, J. Engel, and R. A. Kammerer. 2000. A distinct seven-residue trigger sequence is indispensable for proper coiled-coil formation of the human macrophage scavenger receptor oligomerization domain. J. Biol. Chem. 275:11672-11677.
6. Guilford, W. H., D. E. Dupuis, G. Kennedy, J. Wu, J. B. Patlak, and D. M. Warshaw. 1997. Smooth and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap. Biophys. J. 72: 1006-1021.