C-type natriuretic peptide increases myocardial contractility and sinus rate mediated by guanylyl cyclase-linked natriuretic peptide receptors in isolated, blood-perfused dog heart preparations

Journal of Pharmacology and Experimental Therapeutics

Volumn 286, Issue 1, 1998, Pages 70-76

  Hirose, Masamichi ^a   Furukawa, Yasuyuki ^a   Kurogouchi, Fumio ^a   Nakajima, Koichi ^a   Miyashita, Yusuke ^a   Chiba, Shigetoshi ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; GUANYLATE CYCLASE; ISOBUTYLMETHYLXANTHINE; NATRIURETIC PEPTIDE TYPE C; PROPRANOLOL;

ANIMAL TISSUE; ARTICLE; CHRONOTROPISM; CONTROLLED STUDY; DOG; DRUG EFFECT; HEART MUSCLE CONTRACTILITY; HEART MUSCLE PERFUSION; HORMONE ACTION; INOTROPISM; ISOLATED HEART; NONHUMAN; PRIORITY JOURNAL; SINUS RHYTHM;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; CYCLIC AMP; CYCLIC GMP; DOGS; GUANYLATE CYCLASE; HEART RATE; MYOCARDIAL CONTRACTION; NATRIURETIC PEPTIDE, BRAIN; NATRIURETIC PEPTIDE, C-TYPE; NERVE TISSUE PROTEINS; NITROPRUSSIDE; PERFUSION; POLYSACCHARIDES; PROPRANOLOL; PROTEINS; RECEPTORS, ATRIAL NATRIURETIC FACTOR; SINOATRIAL NODE;

EID: 0031847454     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Beaulieu P, Cardinal R, De Léan A and Lambert C (1996) Direct chronotropic effects of atrial and C-type natriuretic peptides in anesthetized dogs. Br J Pharmacol 118:1790-1796.
2. Beavo JA and Reifsnyder DH (1990) Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors. Trends Pharmacol Sci 11:150-155.
3. Bethke T, Meyer W, Schmitz W, Scholz H, Stein B, Thomas K and Wenzlaff H (1992) Phosphodiesterase inhibition in ventricular cardiomyocytes from guinea-pig hearts. Br J Pharmacol 107:127-133.
4. Bohm M, Morano I, Pieske B and Ruegg JC (1991) Contribution of cAMP-phosphodiesterase inhibition and sensitization of the contractile proteins for calcium to the inotropic effect of pimobendan in the failing human myocardium. Circ Res 68:689-701.
5. Brown LA, Nunez DJR and Wilkins MR (1993) Differential regulation of natriuretic peptide receptor messenger RNAs during the development of cardiac hypertrophy in the rat. J Clin Invest 92:2702-2712.
6. Chiba S (1976) Effects of pentobarbital, verapamil and manganese on the frequency-force relationship of the isolated atrium and ventricle of the dog heart. Eur J Pharmacol 40:225-232.
7. Chiba S, Kimura T and Hashimoto K (1975) Muscarinic suppression of the nicotinic action of acetylcholine on the isolated, blood-perfused atrium of the dog. Naunyn-Schmiedebergs Arch Pharmacol 289:315-325.
8. Chiba S, Kozu TM and Watanabe H (1982) Analysis of cardiac actions of nitroprusside in intact dogs and in isolated atria. Jpn Heart J 23:613-621.
9. Clavell AL, Stingo AJ, Wei, C-M, Heublein DM and Burnett JRJC (1993) C-type natriuretic peptide: a selective cardiovascular peptide. Am J Physiol 264:R590-R594.
10. Cramb G, Banks R, Rugg EL and Aiton JF (1987) Actions of atrial natriuretic peptide (ANP) on cyclic nucleotide concentrations and phosphatidylinositol turnover in ventricular myocytes. Biochem Biophys Res Commun 148:962-970.
11. Diamond J, Ten Eick RE and Trapani AJ (1977) Are increases in cyclic GMP levels responsible for the negative inotropic effects of acetylcholine in the heart ? Biochem Biophys Res Commun 79:912-918.
12. Endoh M and Yamashita S (1981) Differential responses to carbachol, sodium nitroprusside and 8-bromo-guanosine 3′,5′-monophosphatase of canine atrial and ventricular muscle. Br J Pharmacol 73:393-399.
13. Espiner EA (1994) Physiology of natriuretic peptide. J Intern Med 235:527-541.
14. Furukawa Y, Kobayashi M and Chiba S (1980) A pharmacologic analysis of chronotropic and inotropic responses to direct electrical stimulation of the isolated, blood-perfused canine atrium. Jpn Heart J 21:873-882.
15. Furukawa Y, Ogiwara Y, Saegusa K, Akahane K and Chiba S (1989) Differential vagal inhibition of the positive chronotropic and inotropic responses to cardiotonics in the isolated dog atrium. Eur J Pharmacol 161:1-8.
16. Furukawa Y, Saegusa K, Ogiwara Y and Chiba S (1986) Different effectiveness of glucagon on the pacemaker activity and contractility in intact dog hearts and in isolated perfused right atria. Jpn Heart J 27:215-222.
17. Inagami T (1989) Atrial natriuretic factor. J Biol Chem 264:3043-3046.
18. Karasawa Y, Furukawa Y, Ren LM, Takei M, Murakami M, Narita M and Chiba S (1990) Cardiac responses to VIP and VIP-ergic-cholinergic interaction in isolated dog heart preparations. Eur J Pharmacol 187:9-17.
19. Koller KJ, Lowe DG, Bennett GL, Minamino N, Kangawa K, Matsuo H and Goeddel DV (1991) Selective activation of the B-natriuretic peptide receptor by C-type natriuretic peptide (CNP). Science 252:120-123.
20. Koller KJ and Goeddel DV (1992) Molecular biology of the natriuretic peptides and their receptors. Circulation 86:1081-1088.
21. Komatsu Y, Nakao K, Suga S, Ogawa Y, Mukoyama M, Arai H, Shirakami G, Hosoda K, Nakagawa O and Hama N (1991) C-type natriuretic peptide in rats and human. Endocrinology 129:1104-1106.
22. Kumar R, Namiki T and Joyner RW (1997) Effects of cGMP on L-type calcium current of adult and newborn rabbit ventricular cells. Cardiovasc Res 33:573-582.
23. 2+ transport in guinea pig ventricles. J Biol Chem 260:13122-13129.
24. Lohmann SM, Fischmeister R and Walter U (1991) Signal transduction by cGMP in heart. Basic Res Cardiol 86:503-514.
25. Matsuda Y and Morishita Y (1993) HS-142-1: A novel nonpeptide atrial natriuretie peptide antagonist of microbial origin. Cardiovasc Drug Rev 11:45-59.
26. Mukoyama M, Nakao K, Hosoda K, Suga S, Saito Y, Ogawa Y, Shirakami G, Jougasaki M, Obata K, Yasue H, Kambayashi Y, Inouye K and Imura H. (1991) Brain natriuretic peptide (BNP) as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic system, atrial natriuretic peptide and brain natriuretic peptide. J Clin Invest 87:1402-1412.
27. Nakao K, Ogawa Y, Suga S and Imura H (1992) Molecular biology and biochemistry of natriuretic peptide system I: Natriuretic peptides. J Hypertension 10:907-912.
28. Neyses L and Vetter H (1989) Action of atrial natriuretic peptide and angiotensin II on the myocardium: studies in isolated rat ventricular cardiomyocytes. Biochem Biophys Res Commun 163:1435-1443.
29. Nunez DJR, Dickson CM and Brown KJ (1992) Natriuretic peptide receptor mRNA in rat and human heart. J Clin Invest 90:1966-1971.
30. Ogawa Y, Nakao K, Mukoyama M, Hosoda K, Shirakami G, Arai H, Saito Y, Suga S, Jougasaki M and Imura H (1991) Natriuretic peptides as cardiac hormones in normotensive and spontaneously hypertensive rats. The ventricle is a major site of synthesis and secretion of natriuretic peptide. Circ Res 69:491-500.
31. 2+ current in guinea-pig ventricular cells. J Physiol 443:387-404.
32. Rapundalo ST, Solaro J and Kranias EG (1989) Inotropic responses to isoproterenol and phosphodiesterase inhibitors in intact guinea-pig hearts. Comparison of cyclic AMP levels and phosphorylation of sarcoplasmic reticulum and myofibrillar proteins. Circ Res 64:104-111.
33. Shirayama T and Pappano AJ (1996) Biphasic effects of intrapipette cyclic guanosine monophsphate on L-type calcium current and contraction of guinea pig ventricular myocytes. J Pharmacol Exp Ther 279:1274-1281.
34. Song DL, Kohse KP and Murad F (1988) Brain natriuretic factor: Augmentation of cellular cyclic GMP, activation of particulate guanylate cyclase and receptor binding. FEBS Lett 232:125-129.
35. Taniguchi T, Fujiwara J, Lee J and Hidaka H (1979) Effect of acetylcholine on the norepinephrine-induced positive chronotropy and increase in cyclic nucleotides of isolated rabbit sinoatrial node. Circ Res 45:493-504.
36. Vollmar AM, Gerbes AL, Nemer M and Schulz R (1993) Detection of C-type natriuretic peptide (CNP) transcript in the rat heart and immune organs. Endocrinology 132:1872-1874.
37. Wei, C-M, Heublein DM, Perrella MA, Lerman A, Rodeheffer RJ, McGregor CGA, Edwards WD, Schaff HV and Burnett JC (1993) Natriuretic peptide system in human heart failure. Circulation 88:1004-1009.
38. Yonezawa T, Furukawa Y, Lakhe M, Nagashima Y, Hirose M and Chiba S (1996) Pituitary adenylate activating polypeptide (PACAP)-38 activates parasympathetic nerves in isolated, blood-perfused dog atria. Eur J Pharmacol 315:289-296.