Differential expression of the cyclic GMP-stimulated phosphodiesterase PDE2A in human venous and capillary endothelial cells

Journal of Histochemistry and Cytochemistry

Volumn 47, Issue 7, 1999, Pages 895-905

  Sadhu, Krishna ^a   Hensley, Kelly ^a   Florio, Vince A ^a   Wolda, Sharon L ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Capillaries; cGMP stimulated; Endothelial cells; Immunocytochemistry; Microvessels; Phosphodiesterase; Veins

Indexed keywords

PHOSPHODIESTERASE; PROTEIN PDE2A; UNCLASSIFIED DRUG;

ARTICLE; CAPILLARY ENDOTHELIUM; CELLULAR DISTRIBUTION; ENDOTHELIUM CELL; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM;

GLOMERULUS;

EID: 0033033945     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549904700707     Document Type: Article

References (45)

1. Beavo JA, Hardman JG, Sutherland EW (1970) Hydrolysis of cyclic guanosine and adenosine 3′,5′-monophosphates by rat and bovine tissues. J Biol Chem 245:5649-5655
2. Bolger G, Michaeli T, Martins T, St John T, Steiner B, Rodgers L, Riggs M, Wigler M, Ferguson K (1993) A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs. Mol Cell Biol 13:6558-6571
3. Cines DB, Pollak ES, Buck CA, Loscalzo J, Zimmerman GA, McEver RP, Pober JS, Wick TM, Konkle BA, Schwartz BS, Barnathan ES, McCrae KR, Hug BA, Schmidt AM, Stern DM (1998) Endothelial cells in physiology and in pathophysiology of vascular disorders. Blood 91:3527-3561
4. D'Angelo G, Lee H, Weiner RI (1997) cAMP-dependent protein kinase inhibits the mitogenic action of vascular endothelial growth factor and fibroblast growth factor in capillary endothelial cells by blocking Raf activation. J Cell Biochem 67:353-366
5. De Caterina R, Libby P, Peng H-B, Thannickal VJ, Rajavashisth TB, Gimbrone MA, Shin WS, Liao JK (1995) Nitric oxide decreases cytokine-induced endothelial activation. J Clin Invest 96:60-68
6. Fisher DA, Smith JF, Pillar JS, St. Denis SH, Cheng JB (1998) Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase. J Biol Chem 273:15559-15564
7. Ghersa P, Hooft van Huijsduijnen R, Whelan J, Cambet Y, Pescini R, DeLamarter JF (1994) Inhibition of E-selectin gene transcription through a cAMP-dependent protein kinase pathway. J Biol Chem 269:29129-29137
8. Harlow E, Lane DP (1990) Antibodies: A Laboratory Manual. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press
9. Juilfs DM, Fülle H-J, Zhao A, Houslay MD, Garbers DL, Beavo, JA (1997) A subset of olfactory neurons that selectively express cGMP-stimulated phosphodiesterase (PDE2) and guanylyl cyclase-D define a unique olfactory signal transduction pathway. Proc Natl Acad Sci USA 94:3388-3395
10. Kishi Y, Ashikaga T, Numano F (1992) Phosphodiesterases in vascular endothelial cells. Adv Second Messenger Phosphoprotein Res 25:201-213
11. Kishi Y, Ashikaga T, Wantanabe R, Numano F (1994) Atrial natriuretic peptide reduces cyclic AMP by activating cyclic GMP-stimulated phosphodiesterase in vascular endothelial cells. J Cardiovasc Pharmacol 24:351-357
12. Kurose I, Kubes P, Wolf R, Anderson DC, Paulson J, Miyasaka M, Granger DN (1993) Inhibition of nitric oxide production: mechanisms of vascular albumin leakage. Circ Res 73:164-171
13. LaVallie ER, DiBlasio EA, Kovacic S, Grant KL, Schendel PF, McCoy JM (1993) A thioredoxin gene fusion expression system that circumvents inclusion body formation in the E. coli cytoplasm. Biotechnology 11:187-193
14. Liaw L, Schwartz SM (1993) Comparison of gene expression in bovine aortic endothelium in vivo versus in vitro. Differences in growth regulatory molecules. Arterioscler Thromb 13:985-993
15. Loughney K, Ferguson K (1996) Identification and quantification of PDE isoenzymes and subtypes by molecular biological methods. In Schudt C, Dent G, Rabe KF, eds. Phosphodiesterase Inhibitors. New York, Academic Press, 1-19
16. Loughney K, Hill T, Florio VA, Uher L, Rosman GJ, Wolda SL, Jones BA, Howard ML, McAllister-Lucas LM, Sonnenburg WK, Francis SH, Corbin JD, Beavo JA, Ferguson K (1998) Isolation and characterization of cDNAs encoding PDE5A, a human cGMP-binding, cGMP-specific 3′, 5′-cyclic nucleotide phosphodiesterase. Gene 216:139-147
17. Lugnier C, Schini VB (1990) Characterization of cyclic nucleotide phosphodisterases from cultured bovine aortic endothelial cells. Biochem Pharmacol 39:75-84
18. MacFarland RT, Zelus BD, Beavo JA (1991) High concentrations of a cGMP-stimulated phosphodiesterase mediate ANP-induced decreases in cAMP and steroidogenesis in adrenal glomerulosa cells. J Biol Chem 266:136-142
19. Manganiello VC, Tanaka T, Murshima S (1990) Cyclic GMP-stimulated cyclic nucleotide phosphodiesterases. In Beavo J, Houslay M, eds. Cyclic Nucleotide Phosphodiesterases: Structure, Regulation and Drug Action. New York, Wiley, 61-85
20. Martins TJ, Mumby MC, Beavo JA (1982) Purification and characterization of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from bovine tissues. J Biol Chem 57:1973-1979
21. Meacci E, Taira M, Moos M Jr, Smith CJ, Movsesian MA, Degerman E, Belfrage P, Manganiello VC (1992) Molecular cloning and expression of human myocardial cGMP-inhihited cAMP phosphodiesterase. Proc Nad Acad Sci USA 89:3721-3725
22. Meyer DJ, Huxley VH (1992) Capillary hydraulic conductivity is elevated by cGMP-dependent vasodilators. Circ Res 70:382-391
23. Michaeli T, Bloom TJ, Martins T, Loughney K, Ferguson K, Riggs M, Rodgers L, Beavo JA, Wigler M (1993) Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient Saccharomyces cerevisiae. J Biol Chem 268:12925-12932
24. Miki T, Taira M, Hockman S, Shimada F, Lieman J, Napolitano M, Ward D, Taira M, Makino H, Manganiello VC (1996) Characterization of the cDNA and gene encoding human PDE3B, the cGIP1 isoform of the human cyclic GMP-inhibited cyclic nucleotide phosphodiesterase family. Genomics 36:476-485
25. Miot F, Van Haarstert P, Erneux C (1985) Specificity of cGMP binding to a purified cGMP-stimulated phosphodiesterase from bovine adrenal tissue. Eur J Biochem 149:59-65
26. Morandini R, Ghanem G, Portier-LeMarie A, Robaye B, Renaud A, Boeynaems JM (1996) Action of cAMP on expression and release of adhesion molecules in human endothelial cells. Am J Physiol 270:H807-816
27. Murashima S, Tanaka T, Hockman S, Manganiello V (1990) Characterization of particulate cyclic nucleotide phosphodiesterases from bovine brain: purification of a distinct cGMP-stimulated isoenzyme. Biochemistry 29:5285-5292
28. Pober JS, Slowik MR, DeLuca LG, Ritchie AJ (1993) Elevated cyclic AMP inhibits endothelial cell synthesis and expression of TNF-induced endothelial leukocyte adhesion molecule-1, and vascular cell adhesion molecule-1, but not intercellular adhesion molecule-1. J Immunol 150:5114-5123
29. Podzuweit T, Nennstiel P, Müller A (1995) Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl)adenine. Cell Signal 7:733-738
30. Pyne NJ, Cooper ME, Houslay MD (1986) Identification and characterization of both the cytosolic and particulate forms of cyclic GMP-stimulated cyclic AMP phosphodiesterase from rat liver. Biochem J 235:325-334
31. Repaske DR, Corbin JG, Conti M, Goy MF (1993) A cyclic GMP-stimulated cyclic nucleotide phosphodiesterase gene is highly expressed in the limbic system of the rat brain. Neuroscience 56: 673-686
32. Rivet-Bastide M, Vandecasteele G, Hatem S, Verde I, Benardeau A, Mercadier JJ, Fischmeister R (1997) cGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes. J Clin Invest 99:2710-2718
33. Rosman G, Martins TJ, Sonnenburg WK, Beavo JA, Ferguson K, Loughney K (1997) Isolation and characterization of human cDNA encoding a cGMP-stimulated 3′,5′-cyclic nucleotide phosphodiesterase. Gene 191:89-95
34. Soderling SH, Bayuga SJ, Beavo JA (1998a) Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases. J Biol Chem 273:15553-15558
35. Soderling SH, Bayuga SJ, Beavo JA (1998b) Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase. Proc Natl Acad Sci USA 95:8991-8996
36. Sonnenburg WK, Mullaney PJ, Beavo JA (1991) Molecular cloning of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase cDNA. J Biol Chem 266:17655-17661
37. Souness JE, Diocee BK, Martin W, Moodie SA (1990) Pig aortic endothelial-cell cyclic nucleotide phosphodiesterases. Use of phosphodiesterase inhibitors to evaluate their roles in regulating cyclic nucleotide levels in intact cells. Biochem J 266:127-132
38. Suttorp N, Ehreiser P, Hippenstiel S, Fuhrmann M, Krull M, Tenor H, Schudt C (1996a) Hyperpermeability of pulmonary endothelial monolayer: protective role of phosphodiesterase isoenzymes 3 and 4. Lung 174:181-194
39. Suttorp N, Hippenstiel S, Fuhrmann M, Krull M, Podzuweit T (1996b) Role of nitric oxide and phosphodiesterase isoenzyme II for reduction of endothelial hyperpermeability. Am J Physiol 270:C778-785
40. Suttorp N, Weber U, Welsch T, Schudt C (1993) Role of phosphodiesterases in the regulation of endothelial permeability in vitro. J Clin Invest 91:1421-1428
41. Westendorp RGJ, Draijer R, Meinders AE, vanHinsbergh VWM (1994) Cyclic-GMP-mediated decrease in permeability of human umbilical and pulmonary artery endothelial cell monolayers. J Vase Res 31:42-51
42. Whalin ME, Strada SJ, Thompson WJ (1988) Purification and partial characterization of membrane-associated type II (cGMP-activatable) cyclic nucleotide phosphodiesterase from rabbit brain. Biochim Biophys Acta 972:79-94
43. Yamamoto T, Manganiello VC, Vaughan M (1983) Purification and characterization of cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from calf liver. Effects of divalent cations on activity. J Biol Chem 258:12526-12533
44. Yang Q, Paskind M, Bolger G, Thompson WJ, Repaske DR, Cutler LS, Epstein PM (1994) A novel cyclic GMP stimulated phosphodiesterase from rat brain. Biochem Biophys Res Commun 205:1850-1858
45. Yu J, Wolda SL, Frazier ALB, Florio VA, Martins TJ, Snyder PB, Harris EAS, McCaw KN, Farrell CA, Steiner B, Bentley JK, Beavo JA, Ferguson K, Gelinas R (1997) Identification and characterisation of a human calmodulin-stimulated phosphodiesterase PDE1B1. Cell Signal 9:519-529