Leader-body junction sequence of the viral subgenomic mRNAs of porcine reproductive and respiratory syndrome virus isolated in Taiwan

Journal of Veterinary Medical Science

Volumn 64, Issue 11, 2002, Pages 961-965

  Lin, Yu Chieh ^a   Chang, Ruey Yi ^b   Chueh, Ling Ling ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL DONG HWA UNIVERSITY   (Taiwan)

Author keywords

Junction sequence; Porcine reproductive and respiratory syndrome virus; Subgenomic mRNA; Taiwanese isolate

Indexed keywords

ARTERIVIRUS; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS;

MESSENGER RNA; SPLICED LEADER RNA; VIRUS RNA;

ARTERIVIRUS; ARTICLE; GENETICS; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; SEQUENCE ALIGNMENT; TAIWAN; VIRUS GENOME;

BASE SEQUENCE; CLONING, MOLECULAR; GENOME, VIRAL; OPEN READING FRAMES; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; RNA, MESSENGER; RNA, SPLICED LEADER; RNA, VIRAL; SEQUENCE ALIGNMENT; TAIWAN;

EID: 1842854925     PISSN: 09167250     EISSN: None     Source Type: Journal    
DOI: 10.1292/jvms.64.961     Document Type: Article

References (24)

1. Cavanagh, D. 1997. Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch. Virol. 142: 629-633.
2. Chang, C. C., Chung, W. B., Lin, W. M., Weng, C. N., Yang, P. C., Chiu, Y. T., Chang, W. F. and Chu, R. M. 1993. Porcine reproductive and respiratory syndrome (PRRS) in Taiwan. I. Viral isolation. J. Chin. Soc. Vet. Sci. 19: 268-276.
3. Chen, Z., Kuo, L., Rowland, R. R. R., Even, C., Faaberg, K. S. and Plagemann, P. G. W. 1993. Sequences of 3′ end of genome and 5′ end of open reading frame 1a of lactate dehydrogenase-elevating virus and common junction motifs between 5′ leader and bodies of seven subgenomic mRNAs. J. Gen. Virol. 74: 643-660.
4. Chueh, L. L., Lee, K. H., Wang, F. I., Pang, V. F. and Weng, C. N. 1998. Sequence analysis of the nuclecapsid protein gene of the porcine reproductive and respiratory syndrome virus Taiwan MD-001 strain. Adv. Exp. Med. Biol. 440: 795-799.
5. Chueh, L. L. and Lee, K. H. 2001. Sequence analysis of two membrane associated protein genes of porcine reproductive and respiratory syndrome virus, Taiwan MD-001 strain. J. Chin. Soc. Vet. Sci. 27: 80-88.
6. de Boon, J. A., Kleijnen, M. F., Spaan, W. J. M. and Snijder, E. J. 1996. Equine arterivirus subgenomic mRNA synthesis: analysis of leader-body junctions and replicative-form RNAs. J. Virol. 70: 4291-4298.
7. de Vries, A. A. F., Chirnside, E. D., Bredenbeek, P. J., Gravestein, L. A., Horzinek, M. C. and Spaan, W. J. M. 1990. All subgenomic mRNAs of equine arteritis virus contain a common leader sequence. Nucleic Acids Res. 18: 3241-3247.
8. Faaberg, K. S., Elam, M. R., Nelsen, C. J. and Murtaugh, M. P. 1998. Subgenomic RNA 7 is transcribed with different leader-body junction sites in PRRSV (strain VR 2332) infection of CL2621 cells. Adv. Exp. Med. Biol., 440: 275-279.
9. Godeny, E. K., de Vries, A. A. F., Wang, X. C., Smith, S. L. and de Groot, R. J. 1998. Identification of the leader-body junctions for the viral subgenomic mRNAs and organization of the simian hemorrhagic fever virus genome: evidence for gene duplication during arterivirus evolution. J. Virol. 72: 862-867.
10. Meng, X. J., Paul, P. S., Halbur, P. G. and Lum M. A. 1995. Phylogenetic analysis of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): Implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe. Arch. Virol. 140: 745-755.
11. Meng, X. J., Paul, P. S., Morozov, I. and Halbur, P. G. 1996. A nested set of six or seven subgenomic mRNAs is formed in cells infected with different isolates of porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 77: 1265-1270.
12. Meulenberg, J. J. M., Hulst, M. M., de Meijer, E. J., Moonen, P. L., den Besten, A., de Kluyver, E. P., Wensvoort, G and Moormann, R. J. M. 1993a. Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV. Virology 192: 62-72.
13. Meulenberg, J. J. M., Meijer, E. J. D. and Moormann, R. J. M. 1993b. Subgenomic RNAs of Lelystad virus contain a conserved leader-body junction sequence. J. Gen. Virol. 74: 1697-1701.
14. Nelsen, C. J., Murtaugh, M. P. and Faaberg, K. S. 1999. Porcine reproductive and respiratory syndrome virus comparison: divergent evolution of two continents. J. Virol. 73: 270-280.
15. Oleksiewicz, M. B., Botner, A, Nielsen, J. and Storgaard, T. 1999. Determination of 5′-leader sequences from radically disparate strains of porcine reproductive and respiratory syndrome virus reveals the presence of highly conserved sequence motifs. Arch. Virol. 144: 981-987.
16. Pasternak, A. O., Gultyaev, A. P., Spaan, W. J. and Snijder, E. J. 2000. Genetic manipulation of arterivirus alternative mRNA leader-body junction sites reveals tight regulation of structural protein expression. J. Virol. 74: 11642-11653.
17. Rossow, K. D. 1998. Review article: porcine reproductive and respiratory syndrome. Vet. Pathol. 35: 1-20.
18. Snijder, E. J. and Meulenberg, J. J. M. 1998. The molecular biology of arteriviruses. J. Gen. Virol. 79: 961-979.
19. Saito, A., Kanno, T., Murakami, Y., Muramatsu, M. and Yamaguchi, S. 1996. Characteristics of major structural protein coding gene and leader-body sequence in subgenomic mRNA of porcine reproductive and respiratory syndrome virus isolated in Japan. J. Vet. Med. Sci. 58: 377-380.
20. van Marle, G., Dobbe, J. C., Gultyaev, A. P., Luytjes, W., Spaan, W. J. M. and Snijder, E. J. 1999. Arterivirus discontinuous mRNA transcription is guided by base pairing between sense and antisense transcription-regulating sequences. Proc. Natl. Acad. Sci. 96: 12056-12061.
21. Wensvoort, G., Terpstra, C., Pol, J. M., ter Laak, E. A., Bloemraad, M., de Kluyver, E. P., Kragten, C., van Buiten, L., den Besten, A., Wagenaar, F., Broekhuijsen, J. M., Moonen, P. L. J. M., Zetstra, T., de Boer, E. A., Tibben, H. J., de Jong, M. F., van't Veld, P., Groenland, G. L. R., van Gennep, J. A., Voets, M. T., Verheijden, J. H. M. and Braamskamp, J. 1991. Mystery swine disease in the Netherlands: the isolation of Lelystad virus. Vet. Q. 13: 121-130.
22. Wu, W. H., Fang Y., Farwell, R., Steffen-Bien, M., Rowland, R. R. R., Christopher-Hennings, J. and Nelson, E. A. 2001. A 10-kDa structural protein of porcine reproductive and respiratory syndrome virus encoded by ORF2b. Virology 287: 183-191.
23. Yuan, S., Murtaugh, M. P. and Faaberg K. S. 2000. Heterolite subgenomic RNAs are produced in porcine reproductive and respiratory syndrome virus infection. Virology 275: 158-169.
24. Zeng, L., Godeny, E. K., Methven, S. L. and Brinton, M. A. 1995. Analysis of simian hemorragic fever virus (SHFV) subgenomic RNAs, junction sequences, and 5′ leader. Virology 207: 543-548.