Determination of 5'-leader sequences from radically disparate strains of porcine reproductive and respiratory syndrome virus reveals the presence of highly conserved sequence motifs

Archives of Virology

Volumn 144, Issue 5, 1999, Pages 981-987

  Oleksiewicz, M B ^a   Botner A ^a   Nielsen, J ^a   Storgaard, T ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VIRULENCE; VIRUS INFECTION; VIRUS ISOLATION;

5' UNTRANSLATED REGIONS; ANIMALS; BASE SEQUENCE; CONSERVED SEQUENCE; EUROPE; MOLECULAR SEQUENCE DATA; NORTH AMERICA; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; RNA, MESSENGER; RNA, VIRAL; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; SWINE; VIRUS REPLICATION;

EID: 0032988004     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007050050560     Document Type: Article

References (23)

1. Baker SC, Lai MC (1990) An in vitro system for the leader-primed transcription of coronavirus mRNAs. EMBO J 9: 4 173-4 179
2. Benfield DA, Nelson E, Collings JE, Harris L, Goyal SM, Robison D, Christianson WT, Morrison RB, Gorcyca D (1992) Characterization of swine infertility and respiratory syndrome (SIRS) virus (isolate ATCC VR-2332). J Vet Diagn Invest 4: 127-133
3. Bøtner A, Nielsen J. Bille-Hansen V (1994) Isolation of porcine reproductive and respiratory syndrome (PRRS) virus in a Danish swine herd and experimental infection of pregnant gilts with the virus. Vet Microbiol 40: 351-360
4. Bøtner A, Strandbygaard B, Sørensen KJ, Have P, Madsen KG, Smedegaard Madsen E, Alexandersen S (1997) Appearance of acute PRRS-like symptoms in sow herds after vaccination with a modified live PRRS vaccine. Vet Rec 141: 497-499
5. Evans DMA, Dunn G, Minor PD, Schild GC, Cann AJ, Stanway G, Almond JW, Currey K, Maizel Jr JV (1985) Increased neurovirulence associated with a single nucleotide change in a noncoding region of the Sabin type 3 poliovaccine genome. Nature 314: 548-550
6. Hwang Y-K, Brinton MA (1998) A 68-nucleotide sequence, within the 3′ noncoding region of simian hemorrhagic fever Virus negative-strand RNA binds to four MA 104 cell proteins. J Virol 72: 4 341-4 351
7. Jenkins TD, Opitz OG, Okano J, Rustgi AK (1997) Transactivation of the human keratin 4 and Epstein-Barr virus ED-L2 promoters by gut-enriched Krüppel-like factor. J Biol Chem 273: 10 747-10 754
8. Kinney RM, Chang G-J, Tsuchiya KR, Sneider JM, Roehrig JT, Woodward TM, Trent DW (1993) Attenuation of Venezuelan equine encephalitis virus strain TC -83 is encoded by the 5′-noncoding region and the E2 envelope glycoprotein. J Virol 67; 1 269-1 277
9. Liao C-L, Lai MC (1994) Requirement of the 5′-end genomic sequence as an upstream cis-acting element for coronavirus subgenomic mRNA transcription. J Virol 68: 4 727-4 737
10. Madsen KG, Hansen CM, Madsen ES, Strandbygaard B, Bøtner A, Sørensen KJ (1998) Detection of porcine reproductive and respiratory syndrome virus of the American type in Danish swine herds. Arch Virol 143: 1 683-1 700
11. Makino S, Lai MC (1969) High-frequency leader sequence switching during coronavirus defective interfering RNA replication. J Virol 63: 5 285-5 292
12. Meng XJ, Paul PS, Halbur PG, Lum MA (1995a) Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe. Arch Virol 140: 745-755
13. Meng XJ, Paul PS, Halbur PG, Morozov I (1995b) Sequence comparison of open reading frames 2 to 5 of low and high virulence United States isolates of porcine reproductive and respiratory syndrome virus. J Gen Virol 76: 3 181-3 188
14. Meng XJ, Paul PS, Morozov I, Halbur PG (1996) A nested set of six or seven subgenomic mRNAs is formed in cells infected with different isolates of porcine reproductive and respiratory syndrome virus. J Gen Virol 77: 1 265-1 270
15. Meulenberg JJM, Bos-de Ruijter JNA, Van de Graaf R, Wensvoort G, Moormann RJM (1998) Infectious transcripts from cloned genome-length cDNA of porcine reproductive and respiratory syndrome virus. J Virol 72: 380-387
16. Meulenberg JM, Meijer Ed, Moormann R (1993) Subgenomic RNAs of Lelystad virus contain a conserved leader-body junction sequence. J Gen Virol 74: 1 697-1 701
17. Nielsen J, Bøtner A, Oleksiewicz MB (1998) Experimental inoculation of late-term pregnant sows with a field isolate of PRRS vaccine-like virus. Proc. 15th Int. Pig Vet. Soc. Congr., Birmingham, U.K.
18. Okumura K, Sakaguchi G, Takagi S, Naito K, Mimori T, Tgarashi H (1996) Sp1 family proteins recognize the U5 repressive element of the long terminal repeat of human T cell leukemia virus type 1 through binding to the CACCC core motif. Proc Natl Acad Sci USA 271: 12 944-12 950
19. Saito A, Kanno T, Murakami Y, Muramatsu M, Yamaguchi S (1996) Characteristics of major structural protein coding gene and leader-body sequence in subgenomic mRNA of porcine reproductive and respiratory syndrome virus isolated in Japan. J Vet Med Sci 58: 377-380
20. Snijder EJ, Meulenberg JJM (1998) The molecular biology of arteriviruses. J Gen Virol 79: 961-979
21. Sørensen KJ, Strandbygaard B, Bøtner A, Madsen ES, Nielsen J, Have P (1998) Blocking ELISA's for the distinction between antibodies against European and American strains of porcine reproductive and respiratory syndrome (PRRS) virus. Vet Microbiol 60: 169-177
22. Tahara SM, Dietlin TA, Bergmann CC, Nelson GW, Kyuwa S, Anthony RP, Stohlman SA (1994) Coronavirus translational regulation: leader affects mRNA efficiency. Virology 202: 621-630
23. Zhang X, Liao C-L, Lai MC (1993) Coronavirus leader RNA regulates and initiates subgenomic mRNA transcription both in trans and in cis. J Virol 68: 4 738-4 746