Hepatitis B surface antigen (HBsAg) expression in plant cell culture: Kinetics of antigen accumulation in batch culture and its intracellular form

Biotechnology and Bioengineering

Volumn 80, Issue 7, 2002, Pages 812-822

  Smith, Mark L ^a   Mason, Hugh S ^b   Shuler, Michael L ^a,c  

^a Cornell University   (United States)

^b United States Department of Agriculture Agricultural Research Service and Boyce Thompson Institute for Plant Research   (United States)

^c Department of Obstetrics Gynecology   (United States)

Author keywords

HBsAg; Hepatitis B vaccine; Plant cell culture

Indexed keywords

ANTIGENS; ASSAYS; BATCH CELL CULTURE; BILAMINATE MEMBRANES; DIMERS; ELECTRON MICROSCOPY; PLANTS (BOTANY); PROTEINS; VIRUSES; YEAST;

INTRACELLULAR FORMS;

BIOTECHNOLOGY;

HEPATITIS B SURFACE ANTIGEN; ANTIGEN; CELL EXTRACT; HEPATITIS B VACCINE; RECOMBINANT PROTEIN;

ANTIGEN PRESENTATION; ANTIGEN STRUCTURE; ARTICLE; CROSS LINKING; ELECTRON MICROSCOPY; IMMUNOASSAY; IMMUNOGENICITY; IMMUNOLOCALIZATION; KINETICS; NONHUMAN; PLANT CELL CULTURE; PROTEIN EXPRESSION; SOYBEAN; SUCROSE GRADIENT; SUSPENSION CELL CULTURE; TOBACCO; BIOSYNTHESIS; CELL LINE; CLASSIFICATION; COMPARATIVE STUDY; ENDOPLASMIC RETICULUM; GENETICS; INTRACELLULAR FLUID; ISOLATION AND PURIFICATION; METABOLISM; PROTEIN SYNTHESIS; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SPECIES DIFFERENCE; TISSUE DISTRIBUTION; TRANSGENIC PLANT; ULTRASTRUCTURE;

GLYCINE MAX; NICOTIANA TABACUM;

ANTIGENS; CELL EXTRACTS; CELL LINE; ENDOPLASMIC RETICULUM; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; INTRACELLULAR FLUID; KINETICS; PLANTS, GENETICALLY MODIFIED; PROTEIN BIOSYNTHESIS; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOYBEANS; SPECIES SPECIFICITY; TISSUE DISTRIBUTION; TOBACCO;

EID: 1842833950     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10444     Document Type: Article

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