Structural analysis of engineered Bb fragment of complement factor B: Insights into the activation mechanism of the alternative pathway C3-convertase

Molecular Cell

Volumn 14, Issue 1, 2004, Pages 17-28

  Ponnuraj, Karthe ^a   Xu, Yuanyuan ^b   MacOn, Kevin ^a   Moore, Dwight ^a   Volanakis, John E ^c   Narayana, Sthanam V L ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b The University of Alabama at Birmingham   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; DISULFIDE; PROTEIN; PROTEIN BB; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CHEMICAL BOND; CRYSTAL STRUCTURE; ENZYME ACTIVATION; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

ANIMALS; BINDING SITES; COBRA VENOMS; COMPLEMENT C3 CONVERTASE, ALTERNATIVE PATHWAY; COMPLEMENT C3-C5 CONVERTASES; COMPLEMENT C3B; COMPLEMENT INACTIVATOR PROTEINS; COMPLEMENT PATHWAY, ALTERNATIVE; CRYSTALLOGRAPHY, X-RAY; DISULFIDES; ENZYME ACTIVATION; ENZYME INHIBITORS; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; VON WILLEBRAND FACTOR;

EID: 1842816463     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(04)00160-1     Document Type: Article

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