C(8)-Substituted 1-azabicyclo[3.3.1]non-3-enes: A novel scaffold for muscarinic receptor ligands

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 9, 2004, Pages 2357-2367

  Goo Kim, Myoung ^a   Bodor, Erik T ^b   Harden, T Kendall ^b   Kohn, Harold ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

1 Azabicyclo 3.3.1 non 3 enes; Ligands; Muscarinic receptor; Synthesis

Indexed keywords

8 BENZYLOXYMETHYL 3 METHOXYCARBONYL 4 HYDROXY 1 AZABICYCLO[3.3.1]NON 3 ENE; BICYCLO[3.3.1]NONANE DERIVATIVE; LIGAND; MUSCARINIC M1 RECEPTOR; MUSCARINIC M5 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; EVALUATION; NONHUMAN; RECEPTOR AFFINITY; RECEPTOR INTRINSIC ACTIVITY; SUBSTITUTION REACTION;

ANIMALS; AZA COMPOUNDS; BICYCLO COMPOUNDS; COS CELLS; LIGANDS; MUSCARINIC ANTAGONISTS; SPECTRUM ANALYSIS;

EID: 1842767401     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.02.016     Document Type: Article

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