Mouse Bestrophin-2 Is a Bona fide Cl- Channel: Identification of a Residue Important in Anion Binding and Conduction

Journal of General Physiology

Volumn 123, Issue 4, 2004, Pages 327-340

  Qu, Zhiqiang ^a   Fischmeister, Rodolphe ^a   Hartzell, Criss ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chloride channels; Electrophysiology; Ion channel; Ion permeation; Mutagenesis

Indexed keywords

2 AMINOETHYL METHANETHIOSULFONATE; BESTROPHIN; BESTROPHIN 2; BROMIDE 2 TRIMETHYLAMMONIOETHYL METHANETHIOSULFONATE; BROMINE; CHLORIDE CHANNEL; CHLORIDE ION; FLUORINE; IODINE; PROTEIN; SODIUM (2 SULFONATOETHYL) METHANETHIOSULFONATE; SULFONIC ACID DERIVATIVE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANION EXCHANGE; ARTICLE; BINDING SITE; BIOTINYLATION; CELL LINE; CELL MEMBRANE; CELL SURFACE; CHANNEL GATING; CHLORIDE CONDUCTANCE; CHLORIDE CURRENT; CONTROLLED STUDY; ELECTRICITY; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; ION CONDUCTANCE; ION PERMEABILITY; MOUSE; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANIONS; ANTIBODIES; BINDING SITES; CALCIUM; CELL MEMBRANE; CHLORIDE CHANNELS; CHLORIDES; EYE PROTEINS; GENE EXPRESSION; HELA CELLS; HUMANS; ISOTHIOCYANATES; KIDNEY; MEMBRANE POTENTIALS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; PIGMENT EPITHELIUM OF EYE; RABBITS; SULFHYDRYL COMPOUNDS;

EID: 1842686247     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200409031     Document Type: Article

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