메뉴 건너뛰기




Volumn 11, Issue 1, 2004, Pages 67-75

Neurological Dysfunction Associated with Antiphospholipid Syndrome: Histopathological Brain Findings of Thrombotic Changes in a Mouse Model

Author keywords

Antiphospholipid syndrome; Autoantibodies; Mouse; Neurological manifestations; Thrombosis

Indexed keywords

ADENYLYLSULFATE KINASE; BETA2 GLYCOPROTEIN 1; CARDIOLIPIN ANTIBODY; ENDOTHELIAL CELL ANTIBODY; EOSIN; HEMATOXYLIN; IMMUNOGLOBULIN; MONOCLONAL ANTIBODY; PHOSPHOLIPID ANTIBODY; TRITIUM;

EID: 1842683661     PISSN: 17402522     EISSN: None     Source Type: Journal    
DOI: 10.1080/10446670410001670526     Document Type: Article
Times cited : (32)

References (50)
  • 1
    • 0029074352 scopus 로고
    • Early onset of autoimmunity in MRL/++mice following immunization with β2 glycoprotein
    • Aron, A.L., Cuellar, M.L., Brey, R.L., et al. (1995) "Early onset of autoimmunity in MRL/++mice following immunization with β2 glycoprotein", Clin. Exp. Immunol. 101, 78-81.
    • (1995) Clin. Exp. Immunol. , vol.101 , pp. 78-81
    • Aron, A.L.1    Cuellar, M.L.2    Brey, R.L.3
  • 2
    • 0028000905 scopus 로고
    • "Primary", "Secondary" and other variants of the antiphospholipid syndrome
    • Asherson, A.R. and Cervera, R. (1994) ""Primary", "Secondary" and other variants of the antiphospholipid syndrome", Lupus 3, 293-298.
    • (1994) Lupus , vol.3 , pp. 293-298
    • Asherson, A.R.1    Cervera, R.2
  • 4
    • 0026663398 scopus 로고
    • Induction of primary antiphospholipid syndrome in mice by immunizing with a human monoclonal anticardiolipin antibodies (H3)
    • Bakimer, R., Fishman, P., Blank, M., Srendi, B., Djaldetti, M. and Shoenfeld, Y. (1992) "Induction of primary antiphospholipid syndrome in mice by immunizing with a human monoclonal anticardiolipin antibodies (H3)", J. Clin. Investig. 89, 1558-1563.
    • (1992) J. Clin. Investig. , vol.89 , pp. 1558-1563
    • Bakimer, R.1    Fishman, P.2    Blank, M.3    Srendi, B.4    Djaldetti, M.5    Shoenfeld, Y.6
  • 5
    • 0031662442 scopus 로고    scopus 로고
    • Anti-endothelial cell antibody binding makes negatively charged phospholipids accessible to antiphospholipid antibodies
    • Bordron, A., Dueymes, M., Levy, Y., et al. (1998) "Anti-endothelial cell antibody binding makes negatively charged phospholipids accessible to antiphospholipid antibodies", Arthritis Rheum. 41, 1738-1747.
    • (1998) Arthritis Rheum. , vol.41 , pp. 1738-1747
    • Bordron, A.1    Dueymes, M.2    Levy, Y.3
  • 6
    • 0033826474 scopus 로고    scopus 로고
    • Differential diagnosis of central nervous system manifestations of the antiphospholipid antibody syndrome
    • Brey, R.L. (2000) "Differential diagnosis of central nervous system manifestations of the antiphospholipid antibody syndrome", J. Autoimmun. 15, 133-138.
    • (2000) J. Autoimmun. , vol.15 , pp. 133-138
    • Brey, R.L.1
  • 7
    • 0010324673 scopus 로고
    • Nervous system pathology in MRL/lpr and MRL/++mice
    • Brey, R.L. and Teale, J.M. (1992) "Nervous system pathology in MRL/lpr and MRL/++mice", Clin. Exp. Rheumatol. 10, 641-645.
    • (1992) Clin. Exp. Rheumatol. , vol.10 , pp. 641-645
    • Brey, R.L.1    Teale, J.M.2
  • 8
    • 0027430207 scopus 로고
    • Neurologic complications of antiphospholipid antibodies
    • Brey, R.L., Gharavi, A.E. and Lockshin, M.D. (1993) "Neurologic complications of antiphospholipid antibodies", Rheum. Dis. Clin. N. Am. 19, 833-850.
    • (1993) Rheum. Dis. Clin. N. Am. , vol.19 , pp. 833-850
    • Brey, R.L.1    Gharavi, A.E.2    Lockshin, M.D.3
  • 9
    • 0032908439 scopus 로고    scopus 로고
    • Antiphospholipid antibodies permeabilize and depolarize brain synaptoneurosomes
    • Chapman, J., Cohen-Armon, M., Shoenfeld, Y. and Korczyn, A.D. (1999) "Antiphospholipid antibodies permeabilize and depolarize brain synaptoneurosomes", Lupus 8, 127-133.
    • (1999) Lupus , vol.8 , pp. 127-133
    • Chapman, J.1    Cohen-Armon, M.2    Shoenfeld, Y.3    Korczyn, A.D.4
  • 10
    • 0023553282 scopus 로고
    • Multiple cerebral infarctions and dementia associated with anticardiolipin antibodies
    • Coull, B.M., Bourdette, D.N., Goodnight, S.H., Briley, D.P. and Hart, R. (1987) "Multiple cerebral infarctions and dementia associated with anticardiolipin antibodies", Stroke 18, 1107-1112.
    • (1987) Stroke , vol.18 , pp. 1107-1112
    • Coull, B.M.1    Bourdette, D.N.2    Goodnight, S.H.3    Briley, D.P.4    Hart, R.5
  • 12
    • 15844430231 scopus 로고    scopus 로고
    • Pathogenic role of antiendothelial cell antibodies (AECA) in vasculitis: An idiotypic experimental model
    • Damianovich, M., Guilburd, B., George, J., et al. (1996) "Pathogenic role of antiendothelial cell antibodies (AECA) in vasculitis: an idiotypic experimental model", J. Immunol. 156, 4946-4951.
    • (1996) J. Immunol. , vol.156 , pp. 4946-4951
    • Damianovich, M.1    Guilburd, B.2    George, J.3
  • 13
    • 0028941808 scopus 로고
    • Relationship between anti-phospholipid and anti-endothelial cell antibodies III: β2-glycoprotein-I mediates the antibody binding to endothelial membranes and induces the expression of adhesion molecules
    • Del Papa, N., Guidali, L., Spatola, L., et al. (1995) "Relationship between anti-phospholipid and anti-endothelial cell antibodies III: β2-glycoprotein-I mediates the antibody binding to endothelial membranes and induces the expression of adhesion molecules", Clin. Exp. Rheumatol. 13, 179-185.
    • (1995) Clin. Exp. Rheumatol. , vol.13 , pp. 179-185
    • Del Papa, N.1    Guidali, L.2    Spatola, L.3
  • 15
    • 1842744140 scopus 로고
    • Intramural platelet deposition in cerebral vasculopathy of antiphospholipid syndrome
    • Elison, D., Gatter, K., Heryet, A. and Esiri, M. (1995) "Intramural platelet deposition in cerebral vasculopathy of antiphospholipid syndrome", Semin. Arthritis Rheum. 24, 273-281.
    • (1995) Semin. Arthritis Rheum. , vol.24 , pp. 273-281
    • Elison, D.1    Gatter, K.2    Heryet, A.3    Esiri, M.4
  • 16
    • 0030892844 scopus 로고    scopus 로고
    • Flow cytometric detection of circulating activated platelets in primary antiphospholipid syndrome. Correlation with thrombocytopenia and anticardiolipin antibodies
    • Fanelli, A., Bergamini, C., Rapi, S., et al. (1997) "Flow cytometric detection of circulating activated platelets in primary antiphospholipid syndrome. Correlation with thrombocytopenia and anticardiolipin antibodies", Lupus 6, 261-267.
    • (1997) Lupus , vol.6 , pp. 261-267
    • Fanelli, A.1    Bergamini, C.2    Rapi, S.3
  • 17
    • 0026492990 scopus 로고
    • Anticardiolipin antibodies and the risk for ischemic stroke and venous thrombosis
    • Ginsburg, K.S., Liang, H.M., Newcomer, L., et al. (1992) "Anticardiolipin antibodies and the risk for ischemic stroke and venous thrombosis", Ann. Int. Med. 117, 997-1002.
    • (1992) Ann. Int. Med. , vol.117 , pp. 997-1002
    • Ginsburg, K.S.1    Liang, H.M.2    Newcomer, L.3
  • 18
    • 0028354654 scopus 로고
    • Association between antiphospholipid antibodies and epilepsy in patients with SLE
    • Herranz, M.T., Rivier, G., Khamashta, M.A., Blaser, K.U. and Hughes, G.R.V. (1994) "Association between antiphospholipid antibodies and epilepsy in patients with SLE", Arthritis Rheum. 37, 569-571.
    • (1994) Arthritis Rheum. , vol.37 , pp. 569-571
    • Herranz, M.T.1    Rivier, G.2    Khamashta, M.A.3    Blaser, K.U.4    Hughes, G.R.V.5
  • 19
    • 0027288802 scopus 로고
    • Cognitive and neurologic deficits in the MRL/lpr mouse: Clinicopathologic study
    • Hess, D.C., Taormina, M., Thompson, J., et al. (1993) "Cognitive and neurologic deficits in the MRL/lpr mouse: clinicopathologic study", J. Rheumatol. 20, 610-617.
    • (1993) J. Rheumatol. , vol.20 , pp. 610-617
    • Hess, D.C.1    Taormina, M.2    Thompson, J.3
  • 20
    • 0029919622 scopus 로고    scopus 로고
    • Heart valve involvement (Libman-Sack Endocarditis) in the antiphospholipid syndrome
    • Hojnik, M., George, J., Ziporen, L. and Shoenfeld, Y. (1996) "Heart valve involvement (Libman-Sack Endocarditis) in the antiphospholipid syndrome", Circulation 93, 1579-1587.
    • (1996) Circulation , vol.93 , pp. 1579-1587
    • Hojnik, M.1    George, J.2    Ziporen, L.3    Shoenfeld, Y.4
  • 21
    • 0027292423 scopus 로고
    • The antiphospholipid syndrome: Ten years on
    • Hughes, G.R.V. (1993) "The antiphospholipid syndrome: ten years on", Lancet 342, 341-344.
    • (1993) Lancet , vol.342 , pp. 341-344
    • Hughes, G.R.V.1
  • 22
    • 0027690064 scopus 로고
    • Thrombotic cerebral arteriopathy in patients with the antiphospholipid syndrome
    • Hugston, M.D., McCarry, G.A., Sholer, C. and Brumback, M.D. (1993) "Thrombotic cerebral arteriopathy in patients with the antiphospholipid syndrome", Mod. Pathol. 6, 644-653.
    • (1993) Mod. Pathol. , vol.6 , pp. 644-653
    • Hugston, M.D.1    McCarry, G.A.2    Sholer, C.3    Brumback, M.D.4
  • 23
    • 0024600349 scopus 로고
    • Lupus anticoagulant and late onset seizures
    • Inzelberg, R. and Korczyn, A.D. (1989) "Lupus anticoagulant and late onset seizures", Acta Neurol. Scand. 79, 114-118.
    • (1989) Acta Neurol. Scand. , vol.79 , pp. 114-118
    • Inzelberg, R.1    Korczyn, A.D.2
  • 24
    • 0026708996 scopus 로고
    • The lupus anticoagulant and dementia in non-SLE patients
    • Inzelberg, R., Bornstein, N.M., Reider, I. and Korczyn, A.D. (1992) "The lupus anticoagulant and dementia in non-SLE patients", Dementia 3, 140-145.
    • (1992) Dementia , vol.3 , pp. 140-145
    • Inzelberg, R.1    Bornstein, N.M.2    Reider, I.3    Korczyn, A.D.4
  • 25
    • 0034912513 scopus 로고    scopus 로고
    • Hyperactivity in a mouse model of the antiphospholipid syndrome
    • Katzav, A., Pick, C.G., Korczyn, A.D., Oest, E., Blank, M. and Shoenfeld, Y. (2001) "Hyperactivity in a mouse model of the antiphospholipid syndrome", Lupus 7, 494-499.
    • (2001) Lupus , vol.7 , pp. 494-499
    • Katzav, A.1    Pick, C.G.2    Korczyn, A.D.3    Oest, E.4    Blank, M.5    Shoenfeld, Y.6
  • 26
    • 0030875741 scopus 로고    scopus 로고
    • Monoclonal antiphosphatidylserine antibodies react directly with feline and murine central nervous system
    • Kent, M., Alvarez, F., Vogt, E., Fyffe, R., Ng, A.K. and Rote, N. (1997) "Monoclonal antiphosphatidylserine antibodies react directly with feline and murine central nervous system", J. Rheumatol. 24, 1725-1733.
    • (1997) J. Rheumatol. , vol.24 , pp. 1725-1733
    • Kent, M.1    Alvarez, F.2    Vogt, E.3    Fyffe, R.4    Ng, A.K.5    Rote, N.6
  • 27
    • 0025355573 scopus 로고
    • Clinical neurology and brain histopathology in NZB/NZW F1 lupus mice
    • Kier, A.B. (1990) "Clinical neurology and brain histopathology in NZB/NZW F1 lupus mice", J. Comp. Path. 102, 165-177.
    • (1990) J. Comp. Path. , vol.102 , pp. 165-177
    • Kier, A.B.1
  • 28
    • 0028365677 scopus 로고
    • Induction of tissue factor-like activity in monocytes by anticardiolipin antibodies
    • Kornberg, A., Blank, M., Kaufman, S. and Shoenfeld, Y. (1994) "Induction of tissue factor-like activity in monocytes by anticardiolipin antibodies", J. Immunol. 153, 1328-1332.
    • (1994) J. Immunol. , vol.153 , pp. 1328-1332
    • Kornberg, A.1    Blank, M.2    Kaufman, S.3    Shoenfeld, Y.4
  • 29
    • 0024810724 scopus 로고
    • Antiphospholipid syndrome presenting with complex partial seizures and transient ischemic attacks due to widespread small cerebral arterial thrombosis
    • Leach, I.H., Lennox, G. and Jaspan, T. (1989) "Antiphospholipid syndrome presenting with complex partial seizures and transient ischemic attacks due to widespread small cerebral arterial thrombosis", Neuropathol. Appl. Neurobiol. 15, 579-584.
    • (1989) Neuropathol. Appl. Neurobiol. , vol.15 , pp. 579-584
    • Leach, I.H.1    Lennox, G.2    Jaspan, T.3
  • 30
    • 0025124929 scopus 로고
    • Cerebrovascular and neurologic disease associated with antiphospholipid antibodies: 48 Cases
    • Levine, S.R., Deegan, M.J., Futreu, N. and Welch, K.M.A. (1990) "Cerebrovascular and neurologic disease associated with antiphospholipid antibodies: 48 cases", Neurology 40, 1181-1189.
    • (1990) Neurology , vol.40 , pp. 1181-1189
    • Levine, S.R.1    Deegan, M.J.2    Futreu, N.3    Welch, K.M.A.4
  • 31
    • 0031911809 scopus 로고    scopus 로고
    • Massive proteinuria as a main manifestation of primary antiphospholipid syndrome
    • Levy, Y., George, J., Ziporen, L., et al. (1997) "Massive proteinuria as a main manifestation of primary antiphospholipid syndrome", Pathobiology 66, 49-52.
    • (1997) Pathobiology , vol.66 , pp. 49-52
    • Levy, Y.1    George, J.2    Ziporen, L.3
  • 32
    • 0024679638 scopus 로고
    • Vasculopathy in the antiphospholipid syndrome: Thrombosis of vasculitis, or both?
    • Lie, J.T. (1989) "Vasculopathy in the antiphospholipid syndrome: thrombosis of vasculitis, or both?", J. Rheumatol. 16, 713-715.
    • (1989) J. Rheumatol. , vol.16 , pp. 713-715
    • Lie, J.T.1
  • 33
    • 0028203811 scopus 로고
    • Vasculitis in the antiphospholipid syndrome: Culprit or consort?
    • Lie, J.T. (1994) "Vasculitis in the antiphospholipid syndrome: culprit or consort?", J. Rheumatol. 21, 397.
    • (1994) J. Rheumatol. , vol.21 , pp. 397
    • Lie, J.T.1
  • 34
    • 0028347555 scopus 로고
    • Anticardiolipin antisera from lupus patients with seizure reduce a GABA receptor-mediated chloride current in snail neurons
    • Liou, H.H., Wang, C.R., Chou, H.C., et al. (1994) "Anticardiolipin antisera from lupus patients with seizure reduce a GABA receptor-mediated chloride current in snail neurons", Life Sci. 54, 1119-1125.
    • (1994) Life Sci. , vol.54 , pp. 1119-1125
    • Liou, H.H.1    Wang, C.R.2    Chou, H.C.3
  • 36
    • 0028173807 scopus 로고
    • Effect of human IgG antiphospholipid antibodies on a in vivo thrombosis model in mice
    • Pierangeli, S., Barker, J.H., Stikovac, D., et al. (1995) "Effect of human IgG antiphospholipid antibodies on a in vivo thrombosis model in mice", Thromb. Haemost. 71, 670-674.
    • (1995) Thromb. Haemost. , vol.71 , pp. 670-674
    • Pierangeli, S.1    Barker, J.H.2    Stikovac, D.3
  • 37
    • 0031590568 scopus 로고    scopus 로고
    • From antiphospholipid syndrome to antibody-mediated thrombosis
    • Roubey, R.A.S. and Hoffman, M. (1997) "From antiphospholipid syndrome to antibody-mediated thrombosis", Lancet 350, 1491-1493.
    • (1997) Lancet , vol.350 , pp. 1491-1493
    • Roubey, R.A.S.1    Hoffman, M.2
  • 38
    • 18744400496 scopus 로고    scopus 로고
    • Behavioral and cognitive deficits occur only after prolonged exposure of mice to antiphospholipid antibodies
    • Shrot, S., Katzav, A., Korczyn, A.D., et al. (2002) "Behavioral and cognitive deficits occur only after prolonged exposure of mice to antiphospholipid antibodies", Lupus 11, 736-743.
    • (2002) Lupus , vol.11 , pp. 736-743
    • Shrot, S.1    Katzav, A.2    Korczyn, A.D.3
  • 39
    • 0029117843 scopus 로고
    • Inducible platelets adherence to human umbilical vein endothelium by anticardiolipin antibody-positive sera
    • Silver, R.K., Mullen, T.A., Caplan, M.S., O'Connell, P.D. and Ragin, A. (1995) "Inducible platelets adherence to human umbilical vein endothelium by anticardiolipin antibody-positive sera", Am. J. Obstet. Gynecol. 173, 702-707.
    • (1995) Am. J. Obstet. Gynecol. , vol.173 , pp. 702-707
    • Silver, R.K.1    Mullen, T.A.2    Caplan, M.S.3    O'Connell, P.D.4    Ragin, A.5
  • 40
    • 0028883356 scopus 로고
    • Activation of cultured vascular endothelial cells by antiphospholipid antibodies
    • Simantov, R., La Sala, J.M., Lo, S.K., et al. (1995) "Activation of cultured vascular endothelial cells by antiphospholipid antibodies", J. Clin. Investig. 96, 211-221.
    • (1995) J. Clin. Investig. , vol.96 , pp. 211-221
    • Simantov, R.1    La Sala, J.M.2    Lo, S.K.3
  • 41
    • 0025196076 scopus 로고
    • Autoimmune MRL-lpr/lpr mice are an animal model for the secondary antiphospholipid syndrome
    • Smith, H.R., Hansen, C.L., Rose, R. and Canoso, R.T. (1990) "Autoimmune MRL-lpr/lpr mice are an animal model for the secondary antiphospholipid syndrome", J. Rheumatol. 17, 911-915.
    • (1990) J. Rheumatol. , vol.17 , pp. 911-915
    • Smith, H.R.1    Hansen, C.L.2    Rose, R.3    Canoso, R.T.4
  • 42
    • 0026763468 scopus 로고
    • Inhibition of astrocyte proliferation and binding to brain tissue of anticardiolipin antibodies purified from lupus serum
    • Sun, K.H., Liu, W.T., Tsai, C.Y., Liao, T.S., Lin, W.M. and Yu, C.L. (1992) "Inhibition of astrocyte proliferation and binding to brain tissue of anticardiolipin antibodies purified from lupus serum", Ann. Rheum. Dis. 51, 707-712.
    • (1992) Ann. Rheum. Dis. , vol.51 , pp. 707-712
    • Sun, K.H.1    Liu, W.T.2    Tsai, C.Y.3    Liao, T.S.4    Lin, W.M.5    Yu, C.L.6
  • 43
    • 0024554591 scopus 로고
    • A common anti-cardiolipin antibody idiotype in autoimmune disease: Identification using a mouse monoclonal antibody directed against a naturally-occuring anti-phospholipid antibody
    • Sutjita, M., Hohmann, A.R., Comacchio Boey, M.L. and Bradley, J. (1989) "A common anti-cardiolipin antibody idiotype in autoimmune disease: identification using a mouse monoclonal antibody directed against a naturally-occuring anti-phospholipid antibody", Clin. Exp. Immunol. 75, 211-216.
    • (1989) Clin. Exp. Immunol. , vol.75 , pp. 211-216
    • Sutjita, M.1    Hohmann, A.R.2    Comacchio Boey, M.L.3    Bradley, J.4
  • 44
    • 0029125750 scopus 로고
    • Association of antiphospholipid antibodies with central nervous system disease in systemic lupus erythematosus
    • Toubi, E., Khamashta, M.A., Panarra, A. and Hughes, G.R.V. (1995) "Association of antiphospholipid antibodies with central nervous system disease in systemic lupus erythematosus", Am. J. Med. 99, 397-401.
    • (1995) Am. J. Med. , vol.99 , pp. 397-401
    • Toubi, E.1    Khamashta, M.A.2    Panarra, A.3    Hughes, G.R.V.4
  • 45
    • 0030797383 scopus 로고    scopus 로고
    • Prevalence and signification of antinuclear and anticardiolipin antibodies in patients with epilepsy
    • Verrot, D., san-Marco, M., Dravet, C., et al. (1997) "Prevalence and signification of antinuclear and anticardiolipin antibodies in patients with epilepsy", Am. J. Med. 103, 33-37.
    • (1997) Am. J. Med. , vol.103 , pp. 33-37
    • Verrot, D.1    San-Marco, M.2    Dravet, C.3
  • 46
    • 0025995397 scopus 로고
    • Inflammatory central nervous system disease in lupus-prone MRL/lpr mice: Comparative histologic and immunohistochemical findings
    • Vogelweid, C.M., Johnson, G.C., Besch-Williford, C.L., Basler, J. and Walker, S.E. (1991) "Inflammatory central nervous system disease in lupus-prone MRL/lpr mice: comparative histologic and immunohistochemical findings", J. Neuroimmunol. 35, 89-99.
    • (1991) J. Neuroimmunol. , vol.35 , pp. 89-99
    • Vogelweid, C.M.1    Johnson, G.C.2    Besch-Williford, C.L.3    Basler, J.4    Walker, S.E.5
  • 47
    • 0026788175 scopus 로고
    • Neuropathologic findings in multi-infart dementia associated with anticardiolipin antibody
    • Westerman, E.M., Miles, J.M., Backonja, M. and Sundstrom, W.R. (1992) "Neuropathologic findings in multi-infart dementia associated with anticardiolipin antibody", Arthritis Rheum. 35, 1038-1041.
    • (1992) Arthritis Rheum. , vol.35 , pp. 1038-1041
    • Westerman, E.M.1    Miles, J.M.2    Backonja, M.3    Sundstrom, W.R.4
  • 48
    • 0033512274 scopus 로고    scopus 로고
    • International consensus statement on preliminary classification criteria for definite antiphospholipid syndrom
    • Wilson, A., Gharavi, A.E. and Koike, T. (1999) "International consensus statement on preliminary classification criteria for definite antiphospholipid syndrom", Arthritis Rheum. 42, 1309-1311.
    • (1999) Arthritis Rheum. , vol.42 , pp. 1309-1311
    • Wilson, A.1    Gharavi, A.E.2    Koike, T.3
  • 49
    • 8944227500 scopus 로고    scopus 로고
    • Libman-Sacks endocarditis in the antiphospholipid syndrome: Immunopathological findings in deformed heart valves
    • Ziporen, L., Goldberg, I., Arad, M., et al. (1996) "Libman-Sacks endocarditis in the antiphospholipid syndrome: immunopathological findings in deformed heart valves", Lupus 5, 196-205.
    • (1996) Lupus , vol.5 , pp. 196-205
    • Ziporen, L.1    Goldberg, I.2    Arad, M.3
  • 50
    • 0030818836 scopus 로고    scopus 로고
    • Neurological dysfunction and hyperactive behavior associated with antiphospholipid antibodies: A mouse model
    • Ziporen, L., Shoenfeld, Y., Levy, Y. and Korczyn, A.D. (1997) "Neurological dysfunction and hyperactive behavior associated with antiphospholipid antibodies: a mouse model", J. Clin. Investig. 100(3), 613-619.
    • (1997) J. Clin. Investig. , vol.100 , Issue.3 , pp. 613-619
    • Ziporen, L.1    Shoenfeld, Y.2    Levy, Y.3    Korczyn, A.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.