Anti-endothelial cell antibody binding makes negatively charged phospholipids accessible to antiphospholipid antibodies

Arthritis and Rheumatism

Volumn 41, Issue 10, 1998, Pages 1738-1747

  Bordron, Anne ^a   Dueymes, Maryvonne ^a   Levy, Yair ^b   Jamin, Christophe ^a   Ziporen, Lea ^b   Piette, Jean Charles ^c   Shoenfeld, Yehuda ^b   Youinou, Pierre ^a,d  

^a Inst Synergie des Sci et de la S   (France)

^b SHEBA MEDICAL CENTER   (Israel)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA2 GLYCOPROTEIN 1; CARDIOLIPIN; LIPOCORTIN 5; MONOCLONAL ANTIBODY; PHOSPHATIDYLSERINE; PHOSPHOLIPID ANTIBODY;

ANTIBODY SPECIFICITY; ANTIGEN BINDING; APOPTOSIS; ARTICLE; CELL MEMBRANE; ENDOTHELIUM CELL; FLUORESCENCE; HUMAN; HUMAN CELL; PATHOGENICITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTEMIC SCLEROSIS;

ANIMALS; ANTIBODIES, ANTIPHOSPHOLIPID; ANTIBODY FORMATION; ANTIBODY SPECIFICITY; APOPTOSIS; AUTOANTIBODIES; BINDING SITES, ANTIBODY; ENDOTHELIUM; HUMANS; MICE; PHOSPHATIDYLSERINES;

EID: 0031662442     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(199810)41:10<1738::AID-ART6>3.0.CO;2-7     Document Type: Article

References (48)

1. Hughes GRV. The antiphospholipid syndrome: ten years on. Lancet 1993;342:341-4.
2. Mackworth-Young CG. Antiphospholipid antibodies and disease. Br J Rheumatol 1995;34:1009-30.
3. 2 glycoprotein I (apolipoprotein H). Proc Natl Acad Sci U S A 1990;87: 4120-4.
4. Galli M, Cornfurius P, Maassen C, Hembker HC, de Baets MH, van Breda-Vriesman PJC, et al. Anticardiolipin antibodies directed, not to cardiolipin, but to a plasma protein cofactor. Lancet 1990;335:1544-7.
5. Matsuura E, Igarashi Y, Fujimoto M, Ichikawa K, Koike T. Anticardiolipin cofactor(s) and differential diagnosis of autoimmune disease. Lancet 1990;336:177-8.
6. Roubey RAS. Immunology of the antiphospholipid antibody syndrome. Arthritis Rheum 1996;39:1444-54.
7. 2-glycoprotein I. Thromb Haemost 1992;67:499-502.
8. 2-glycoprotein I (apolipoprotein H). J Clin Invest 1992;90:1105-9.
9. Meroni PL, Youinou P. Endothelial cell antibodies. In: Peter JB, Shoenfeld Y, editors. Autoantibodies. Amsterdam: Elsevier Science; 1996. p. 245-52.
10. Youinou P, Meroni PL, Khamashta MA, Shoenfeld Y. A need for standardization of the antiendothelial cell antibody test. Immunol Today 1995;16:363-4.
11. Salojin KV, Le Tonquèze M, Nassonov EL, Blouch MT, Baronov AA, Saraux A, et al. Antiendothelial cell antibodies in patients with various forms of vasculitis. Clin Exp Rheumatol 1996;14: 163-9.
12. Meroni PL. What is going to happen tomorrow in the field of antiendothelial cell autoantibodies related to vasculitis? Ann Med Interne (Paris) 1994;145:467-8.
13. Bretscher MS. Asymmetrical lipid bilayer structure for biological membranes. Nature 1972;236:11-2.
14. Hasegawa I, Suzuki T, Ishii S, Takakuwa R, Tanaka K. Establishment of two distinct anticardiolipin antibody-producing cell lines from the same individual by Epstein-Barr virus transformation. Thromb Res 1994;74:77-84.
15. 2-glycoprotein I in the antiphospholipid antibody binding to endothelial cells. Lupus 1995;4:179-86.
16. 2-glycoprotein I mediates the antibody binding to endothelial membranes and induces the expression of adhesion molecules. Clin Exp Rheumatol 1995;13:179-85.
17. Simantov R, Lasala JM, Lo SK, Gharavi AE, Sammaritano LR, Salmon JE, et al. Activation of cultured vascular endothelial cell by antiphospholipid antibodies. J Clin Invest 1995;96:2211-9.
18. Hasselaar P, Derksen RHWM, Blokijl L, de Groot PG. Cross-reactivity of antibodies against cardiolipin, DNA, endothelial cells and blood platelets. Thromb Haemost 1990;63:169-73.
19. Hess DC, Shepard JC, Adams RJ. Increased immunoglobulin binding to cerebral endothelium in patients with antiphospholipid antibodies. Stroke 1993;24:994-9.
20. 2-glycoprotein I and, through it, that of IgG antiphospholipid antibodies: studies in platelets of patients with antiphospholipid syndrome and normal subjects. J Autoimmun 1994;7:335-48.
21. Alarcón-Segovia D. Pathogenic potential of antiphospholipid antibodies. J Rheumatol 1988;15:890-3.
22. Bordron A, Dueymes M, Levy Y, Leroy JP, Jamin C, Piette JC, et al. The binding of some human antiendothelial cell antibodies induces endothelial cell apoptosis. J Clin Invest 1998;101:2029-35.
23. Fadok VA, Voelker DR, Campbell PA, Cohen JJ, Bratton DL, Henson PM. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 1992;148:2207-15.
24. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7.
25. McNeil HP, Krilis SA, Chesterman CN. Purification of antiphospholipid antibody using a new affinity method. Thromb Res 1988;52:641-8.
26. Damianovich M, Gilburd B, George J, Del Papa N, Afek A, Goldberg I, et al. Pathogenic role of antiendothelial cell antibodies in vasculitis: an idiotypic experimental model. J Immunol 1996; 156:4946-51.
27. Levy Y, Gilburd B, George J, Del Papa N, Mallone R, Damianovich M, et al. Characterization of murine monoclonal antiendothelial cell antibodies (AECA) produced by idiotypic manipulation with human AECA. Int Immunol. In press.
28. Gilburd B, George J, Damianovich M, Blank M, Del Papa N, Meroni PL, et al. Monoclonal murine anti-endothelial cell antibodies (AECA) produced by idiotypic manipulation with human AECA. Hybridoma. In press.
29. Andree HAM, Reutelingsperger CPM, Haupman R, Hembker HC, Hermens WT, Willems GM. Binding of vascular anticoagulant α to plasma phospholipid bilayers. J Biol Chem 1990;265: 4923-9.
30. 2-glycoprotein I in the rat: isolation from serum and demonstration in lipoprotein density fractions. Int J Biochem 1980;11:265-70.
31. Jaffe EA, Nachman RI, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins: identification by morphologic and immunologic criteria. J Clin Invest 1973;52: 2745-56.
32. Winzler C, Rovere P, Rescigno M, Granucci F, Penna G, Adorini L, et al. Maturation stages of mouse dendritic cells in growth-factor-dependent long-term cultures. J Exp Med 1997;185:317-28.
33. 2-glycoprotein I and clinical manifestations in patients with systemic lupus erythematosus. Arthritis Rheum 1996;39:1466-74.
34. Meroni PL, Del Papa N, Gambini D, Tincani A, Balestrieri G. Antiphospholipid antibodies and endothelial cells. Lupus 1994;3: 267-9.
35. McCrae KR, DeMichele A, Samuels P, Roth D, Kuo A, Meng QH, et al. Detection of endothelial cell-reactive immunoglobulin in patients with antiphospholipid antibodies. Br J Haematol 1991;79:595-605.
36. 2-glycoprotein I and anticardiolipin antibody binding to resting and activated cultured human endothelial cells. J Rheumatol 1996;23:1543-9.
37. 2-glycoprotein I with phospholipid membranes [abstract]. Arthritis Rheum 1995;38 Suppl 9:S211.
38. Cines DB, Lyss AP, Bina M, Corkey R, Kefalides NA, Friedman HM. Fc and C3 receptors induced by Herpes simplex virus on cultured endothelial cells. J Clin Invest 1992;69:123-8.
39. Lindsey NJ, Dawson RA, Henderson FI, Greaves M, Hughes P. Stimulation of von Willebrand factor antigen release by immunoglobulin from thrombosis prone patients with systemic lupus erythematosus and the antiphospholipid syndrome. Br J Rheumatol 1993;32:123-6.
40. Boehme MWJ, Schmitt WH, Youinou P, Stremmel W, Gross WL. Clinical relevance of elevated thrombomodulin and soluble E-selectin in patients with Wegener's granulomatosis and other systemic vasculitis. Am J Med 1996;101:387-94.
41. Manfredi AA, Rovere P, Galati G, Heltai S, Bozzolo E, Soldini L, et al. Apoptotic cell clearance in systemic lupus erythematosus. I. Opsonization by antiphospholipid antibodies. Arthritis Rheum 1998;41:205-14.
42. 2-glycoprotein I. Arthritis Rheum 1998;41:215-23.
43. Nakamura N, Shidara Y, Kawagushi N, Azuma C, Mitsuda N, Onishi S, et al. Lupus anticoagulant autoantibody induces apoptosis in umbilical vein endothelial cells: involvement of annexin V. Biochem Biophys Res Commun 1994;205:1488-93.
44. Dubois T, Bisagni-Faure A, Coste J, Mavoungou E, Menkès CJ, Russo-Marie F, et al. High levels of antibodies to annexins V and VI in patients with rheumatoid arthritis. J Rheumatol 1995;22: 1230-4.
45. Verhoven B, Schlegel RA, Williamson P. Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal on apoptotic cells. J Exp Med 1995;182:1557-601.
46. Goldman D, Phillips G, Baek K, Petri M. Binding of SLE antibodies to apoptotic endothelial cells [abstract]. Arthritis Rheum 1995;38 Suppl 9:S214.
47. Rosen A, Schlissel M, Petri M, Casciola-Rosen L. Antiphospholipid antibodies bind to the surface of apoptotic cells and abolish their procoagulant activity [abstract]. Arthritis Rheum 1995;38 Suppl 9:S267.
48. Page C, Rose M, Yacoub M, Pigott R. Antigenic heterogeneity of vascular endothelium 1992;141:673-83.