Status of the DPC4 tumor suppressor gene in sporadic colon adenocarcinoma of Croatian patients: Identification of a novel somatic mutation

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 548, Issue 1-2, 2004, Pages 61-73

  Popović Hadžija, Marijana ^a   Radoševic, Senka ^b   Kovačević, Duje ^c   Lukač, Josip ^c   Hadžija, Mirko ^a   Spaventi, Radan ^b   Pavelić, Krešimir ^a   Kapitanović, Sanja ^a  

^a RUDER BO KOVI INSTITUTE   (Croatia)

^b PLIVA CROATIA LTD   (Croatia)

^c SESTRE MILOSRDNICE UNIVERSITY HOSPITAL   (Croatia)

Author keywords

Colon adenocarcinoma; DPC4; Loss of heterozygosity; Tumor suppressor gene

Indexed keywords

MICROSATELLITE DNA; PRIMER DNA; SMAD4 PROTEIN;

ADULT; AGED; ALLELE; ARTICLE; CARCINOGENESIS; CODON; COLON ADENOCARCINOMA; COLORECTAL CARCINOMA; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CROATIA; DNA FLANKING REGION; DNA SEQUENCE; EXON; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC CODE; GENETIC POLYMORPHISM; HETEROZYGOSITY; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MUTATION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE; TUMOR VOLUME;

ADULT; AGED; AGED, 80 AND OVER; BASE SEQUENCE; CHROMOSOMES, HUMAN, PAIR 18; COLORECTAL NEOPLASMS; CROATIA; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; SMAD4 PROTEIN; TRANS-ACTIVATORS;

EID: 1842562151     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2003.12.018     Document Type: Article

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