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Volumn 71, Issue 3, 2004, Pages 123-128

Modulation of multidrug-resistance-associated P-glycoprotein in human U-87 MG and HUV-ECC cells with antisense oligodeoxynucleotides to MDR1 mRNA

Author keywords

Antisense treatment; Endothelial cell line; Glioblastoma; MDR 1 gene; Multidrug resistance; Oligonucleotides; P glycoprotein

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; DOXORUBICIN; GLYCOPROTEIN P; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1;

EID: 1842508241     PISSN: 10152008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000076466     Document Type: Article
Times cited : (14)

References (47)
  • 1
    • 0024292717 scopus 로고
    • An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene
    • Choi KH, Chen CJ, Kriegler M, Roninson IB: An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene. Cell 1988;53:519-529.
    • (1988) Cell , vol.53 , pp. 519-529
    • Choi, K.H.1    Chen, C.J.2    Kriegler, M.3    Roninson, I.B.4
  • 2
    • 0033404139 scopus 로고    scopus 로고
    • Multiple recognition of various amphiphilic molecules by the multidrug resistance P-glycoprotein: Molecular mechanisms and pharmacological consequences coming from functional interactions between various drugs
    • Orlowski S, Garrigos M: Multiple recognition of various amphiphilic molecules by the multidrug resistance P-glycoprotein: Molecular mechanisms and pharmacological consequences coming from functional interactions between various drugs. Anticancer Res 1999;19:3100-3124.
    • (1999) Anticancer Res , vol.19 , pp. 3100-3124
    • Orlowski, S.1    Garrigos, M.2
  • 3
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman MM, Pastan I: Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993;62:385-427.
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 4
    • 0028224534 scopus 로고
    • Cell biological mechanisms of multidrug resistance in tumors
    • Simon SM, Schindler M: Cell biological mechanisms of multidrug resistance in tumors. Proc Natl Acad Sci USA 1994;91:3497-3504.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3497-3504
    • Simon, S.M.1    Schindler, M.2
  • 6
    • 0028234560 scopus 로고
    • Functional expression of P-glycoproteins in secretory vesicles
    • Ruetz S, Gros P: Functional expression of Pglycoproteins in secretory vesicles. J Biol Chem 1994;269:12277-12284.
    • (1994) J Biol Chem , vol.269 , pp. 12277-12284
    • Ruetz, S.1    Gros, P.2
  • 7
    • 0030916246 scopus 로고    scopus 로고
    • Up-regulation of P-glycoprotein expression in rat liver cells by acute doxorubicin treatment
    • Fardel O, Lecureur V, Daval S, Corlu A, Guilouzo A: Up-regulation of P-glycoprotein expression in rat liver cells by acute doxorubicin treatment. Eur J Biochem 1997;246:186-192.
    • (1997) Eur J Biochem , vol.246 , pp. 186-192
    • Fardel, O.1    Lecureur, V.2    Daval, S.3    Corlu, A.4    Guilouzo, A.5
  • 9
    • 0030867812 scopus 로고    scopus 로고
    • Cellular pharmacology of lipophilic anthracyclines in human tumor cells in culture selected for resistance to doxorubicin
    • Bennis S, Faure P, Chapey C, Hu YP, Fourche J, El Yamani J, Robert J: Cellular pharmacology of lipophilic anthracyclines in human tumor cells in culture selected for resistance to doxorubicin. Anticancer Drugs1997;8:610-617.
    • (1997) Anticancer Drugs , vol.8 , pp. 610-617
    • Bennis, S.1    Faure, P.2    Chapey, C.3    Hu, Y.P.4    Fourche, J.5    El Yamani, J.6    Robert, J.7
  • 10
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics Adriamycin and daunorubicin
    • Gewirtz DA: A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics Adriamycin and daunorubicin. Biochem Pharmacol 1999;57:727-741.
    • (1999) Biochem Pharmacol , vol.57 , pp. 727-741
    • Gewirtz, D.A.1
  • 11
    • 0029150003 scopus 로고
    • Chemosensitisation of spontaneous multidrug resistance by a 1,4-dihydropyridine analogue and verapamil in human glioma cell lines overexpressing MRP or MDR1
    • Abe T, Koike K, Ohga T, Kubo T, Wada M, Kohno K, Mori T, Hidaka K, Kuwano M: Chemosensitisation of spontaneous multidrug resistance by a 1,4-dihydropyridine analogue and verapamil in human glioma cell lines overexpressing MRP or MDR1. Br J Cancer 1995;72:418-423.
    • (1995) Br J Cancer , vol.72 , pp. 418-423
    • Abe, T.1    Koike, K.2    Ohga, T.3    Kubo, T.4    Wada, M.5    Kohno, K.6    Mori, T.7    Hidaka, K.8    Kuwano, M.9
  • 12
    • 0028816350 scopus 로고
    • A phase III randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma: A Southwest Oncology Group study
    • Dalton WS, Crowley JJ, Salmon S, Grogan TM, Rodgers Laufman L, Weiss GR, Bonnet JD: A phase III randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma: A Southwest Oncology Group study. Cancer 1995;75:815-820.
    • (1995) Cancer , vol.75 , pp. 815-820
    • Dalton, W.S.1    Crowley, J.J.2    Salmon, S.3    Grogan, T.M.4    Rodgers Laufman, L.5    Weiss, G.R.6    Bonnet, J.D.7
  • 13
    • 0033383637 scopus 로고    scopus 로고
    • Digitoxin is a potential anticancer agent for several types of cancer
    • Haux J: Digitoxin is a potential anticancer agent for several types of cancer. Med Hypotheses 1999;53:543-548.
    • (1999) Med Hypotheses , vol.53 , pp. 543-548
    • Haux, J.1
  • 14
    • 0042526079 scopus 로고    scopus 로고
    • Repetitive doxorubicin treatment of glioblastoma enhances the PGP expression - A special role for endothelial cells
    • in press
    • Rittierodt M, Harada K: Repetitive doxorubicin treatment of glioblastoma enhances the PGP expression - A special role for endothelial cells. Exp Toxicol Pathol 2003, in press.
    • (2003) Exp Toxicol Pathol
    • Rittierodt, M.1    Harada, K.2
  • 16
    • 0032700356 scopus 로고    scopus 로고
    • Importance of nucleotide sequence and chemical modifications of antisense oligonucleotides
    • Agrawal S: Importance of nucleotide sequence and chemical modifications of antisense oligonucleotides. Biochim Biophys Acta 1999;1489:53-68.
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 53-68
    • Agrawal, S.1
  • 17
    • 0032697941 scopus 로고    scopus 로고
    • Two problems in antisense biotechnology: In vitro delivery and the design of antisense experiments
    • Stein CA: Two problems in antisense biotechnology: In vitro delivery and the design of antisense experiments. Biochim Biophys Acta 1999;1489:45-52.
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 45-52
    • Stein, C.A.1
  • 18
    • 0034077645 scopus 로고    scopus 로고
    • Sequence dependence of energy transfer in DNA oligonucleotides
    • Xu DG, Nordlund TM: Sequence dependence of energy transfer in DNA oligonucleotides. Biophys J 2000;78:1042-1058.
    • (2000) Biophys J , vol.78 , pp. 1042-1058
    • Xu, D.G.1    Nordlund, T.M.2
  • 19
    • 0026738906 scopus 로고
    • Genetic aspects of multidrug resistance
    • Biedler LJ: Genetic aspects of multidrug resistance. Cancer 1992;70(suppl):1799-1809.
    • (1992) Cancer , vol.70 , Issue.SUPPL. , pp. 1799-1809
    • Biedler, L.J.1
  • 20
    • 0026073186 scopus 로고
    • Genetic mechanisms of drug resistance. A review
    • Borst P: Genetic mechanisms of drug resistance. A review. Acta Oncol 1991;30:87-105.
    • (1991) Acta Oncol , vol.30 , pp. 87-105
    • Borst, P.1
  • 21
    • 0024414605 scopus 로고
    • Structure and expression of the human MDR (P-glycoprotein) gene family
    • Chin JE, Soffir R, Noonan KE, Choi K, Roninson IB: Structure and expression of the human MDR (P-glycoprotein) gene family. Mol Cell Biol 1989;9:3808-3820.
    • (1989) Mol Cell Biol , vol.9 , pp. 3808-3820
    • Chin, J.E.1    Soffir, R.2    Noonan, K.E.3    Choi, K.4    Roninson, I.B.5
  • 22
    • 0032783884 scopus 로고    scopus 로고
    • Multidrug resistance in human tumors - Molecular diagnosis and clinical significance
    • Ramachandran C, Melnick SJ: Multidrug resistance in human tumors - Molecular diagnosis and clinical significance. Mol Diagn 1999;4:81-94.
    • (1999) Mol Diagn , vol.4 , pp. 81-94
    • Ramachandran, C.1    Melnick, S.J.2
  • 23
    • 0025176784 scopus 로고
    • P-glycoproteins in pathology: The multidrug resistance gene family in humans
    • Weinstein RS, Kuszak JR, Kluskens LF, Coon JS: P-glycoproteins in pathology: The multidrug resistance gene family in humans. Hum Pathol 1990;21:34-48.
    • (1990) Hum Pathol , vol.21 , pp. 34-48
    • Weinstein, R.S.1    Kuszak, J.R.2    Kluskens, L.F.3    Coon, J.S.4
  • 24
    • 0030880937 scopus 로고    scopus 로고
    • Identification of a new P-glycoprotein-like ATP-binding cassette transporter gene that is overexpressed during hepatocarcinogenesis
    • Furuya KN, Bradley G, Sun D, Schuetz EG, Schuetz JD: Identification of a new P-glycoprotein-like ATP-binding cassette transporter gene that is overexpressed during hepatocarcinogenesis. Cancer Res 1997;57:3708-3716.
    • (1997) Cancer Res , vol.57 , pp. 3708-3716
    • Furuya, K.N.1    Bradley, G.2    Sun, D.3    Schuetz, E.G.4    Schuetz, J.D.5
  • 25
    • 0028961304 scopus 로고
    • Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators
    • Tang-Wai DF, Kajiji S, DiCapua F, de Graaf D, Roninson IB, Gros P: Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators. Biochemistry 1995;34:32-39.
    • (1995) Biochemistry , vol.34 , pp. 32-39
    • Tang-Wai, D.F.1    Kajiji, S.2    DiCapua, F.3    De Graaf, D.4    Roninson, I.B.5    Gros, P.6
  • 26
    • 0032321699 scopus 로고    scopus 로고
    • The ABC family of multidrug transporters in microorganisms
    • van Veen HW, Konings WN: The ABC family of multidrug transporters in microorganisms. Biochim Biophys Acta 1998;1365:31-36.
    • (1998) Biochim Biophys Acta , vol.1365 , pp. 31-36
    • Van Veen, H.W.1    Konings, W.N.2
  • 28
    • 0030838009 scopus 로고    scopus 로고
    • The multidrugresistance P-glycoprotein (Pgp, MDR1) is an early marker of blood-brain barrier development in the microvessels of the developing human brain
    • Schumacher U, Mollgard K: The multidrugresistance P-glycoprotein (Pgp, MDR1) is an early marker of blood-brain barrier development in the microvessels of the developing human brain. Histochem Cell Biol 1997;108:179-182.
    • (1997) Histochem Cell Biol , vol.108 , pp. 179-182
    • Schumacher, U.1    Mollgard, K.2
  • 32
    • 0030810103 scopus 로고    scopus 로고
    • Immunohistochemical expression of P-glycoprotein and glutathione S-transferases in cerebral gliomas and response to chemotherapy
    • von Bossanyi P, Diete S, Dietzmann K, Warich-Kirches M, Kirches E: Immunohistochemical expression of P-glycoprotein and glutathione S-transferases in cerebral gliomas and response to chemotherapy. Acta Neuropathol 1997;94:605-611.
    • (1997) Acta Neuropathol , vol.94 , pp. 605-611
    • Von Bossanyi, P.1    Diete, S.2    Dietzmann, K.3    Warich-Kirches, M.4    Kirches, E.5
  • 33
    • 0031819596 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein: Rapid assessment of its implication in blood-brain barrier integrity and drug transport to the brain by an in vitro model of the blood-brain barrier
    • Fenart L, Buee-Scherrer V, Descamps L, Duhem C, Poullain MG, Cecchelli R, Dehouck MP: Inhibition of P-glycoprotein: Rapid assessment of its implication in blood-brain barrier integrity and drug transport to the brain by an in vitro model of the blood-brain barrier. Pharm Res 1998;15:993-1000.
    • (1998) Pharm Res , vol.15 , pp. 993-1000
    • Fenart, L.1    Buee-Scherrer, V.2    Descamps, L.3    Duhem, C.4    Poullain, M.G.5    Cecchelli, R.6    Dehouck, M.P.7
  • 34
    • 0023555850 scopus 로고
    • The blood-brain barrier: Interacters between endothelial cells and astrocytes
    • Goldstein GW: The blood-brain barrier: Interacters between endothelial cells and astrocytes. Mead Johnson Symp Perinat Dev Med 1987;29:15-17.
    • (1987) Mead Johnson Symp Perinat Dev Med , vol.29 , pp. 15-17
    • Goldstein, G.W.1
  • 36
    • 0027092617 scopus 로고
    • Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells
    • Hegmann EJ, Bauer HC, Kerbel RS: Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells. Cancer Res 1992;52:6969-6975.
    • (1992) Cancer Res , vol.52 , pp. 6969-6975
    • Hegmann, E.J.1    Bauer, H.C.2    Kerbel, R.S.3
  • 37
    • 0027373799 scopus 로고
    • Human fetal astrocytes induce the expression of blood-brain barrier specific proteins by autologous endothelial cells
    • Hurwitz AA, Berman JW, Rashbaum WK, Lyman WD: Human fetal astrocytes induce the expression of blood-brain barrier specific proteins by autologous endothelial cells. Brain Res 1993;625:238-243.
    • (1993) Brain Res , vol.625 , pp. 238-243
    • Hurwitz, A.A.1    Berman, J.W.2    Rashbaum, W.K.3    Lyman, W.D.4
  • 38
    • 0032936851 scopus 로고    scopus 로고
    • The cell biology of the blood-brain barrier
    • Rubin LL, Staddon JM: The cell biology of the blood-brain barrier. Annu Rev Neurosci 1999;22:11-28.
    • (1999) Annu Rev Neurosci , vol.22 , pp. 11-28
    • Rubin, L.L.1    Staddon, J.M.2
  • 39
    • 0027998226 scopus 로고
    • In vivo evidence for ATP-dependent and P-glycoprotein-mediated transport of cyclosporin A at the blood-brain barrier
    • Sakata A, Tamai I, Kawazu K, Deguchi Y, Ohnishi T, Saheki A, Tsuji A: In vivo evidence for ATP-dependent and P-glycoprotein-mediated transport of cyclosporin A at the bloodbrain barrier. Biochem Pharmacol 1994;48:1989-1992.
    • (1994) Biochem Pharmacol , vol.48 , pp. 1989-1992
    • Sakata, A.1    Tamai, I.2    Kawazu, K.3    Deguchi, Y.4    Ohnishi, T.5    Saheki, A.6    Tsuji, A.7
  • 40
    • 0027290876 scopus 로고
    • Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein
    • Tsuji A, Tamai I, Sakata A, Tenda Y, Terasaki T: Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein. Biochem Pharmacol 1993;46:1096-1099.
    • (1993) Biochem Pharmacol , vol.46 , pp. 1096-1099
    • Tsuji, A.1    Tamai, I.2    Sakata, A.3    Tenda, Y.4    Terasaki, T.5
  • 41
    • 0032678857 scopus 로고    scopus 로고
    • Expression of the multidrug-resistance P-glycoprotein (Pgp, MDR-1) by endothelial cells of the neovasculature in central nervous system tumors
    • Sawada T, Kato Y, Sakayori N, Takekawa Y, Kobayashi M: Expression of the multidrug-resistance P-glycoprotein (Pgp, MDR-1) by endothelial cells of the neovasculature in central nervous system tumors. Brain Tumor Pathol 1999;16:23-27.
    • (1999) Brain Tumor Pathol , vol.16 , pp. 23-27
    • Sawada, T.1    Kato, Y.2    Sakayori, N.3    Takekawa, Y.4    Kobayashi, M.5
  • 42
    • 0034651955 scopus 로고    scopus 로고
    • Identification, purification and partial characterisation of an oligonucleotide receptor in membranes of HegG2 cells
    • Diesbach P, Berens C, N'Kuli F, Monsigny M, Sonveaux E, Wattiez R, Courtoy PJ: Identification, purification and partial characterisation of an oligonucleotide receptor in membranes of HegG2 cells. Nucleic Acids Res 2000;28:868-874.
    • (2000) Nucleic Acids Res , vol.28 , pp. 868-874
    • Diesbach, P.1    Berens, C.2    N'Kuli, F.3    Monsigny, M.4    Sonveaux, E.5    Wattiez, R.6    Courtoy, P.J.7
  • 43
    • 0026336817 scopus 로고
    • Oligonucleotides as therapeutic agents
    • Cohen JS: Oligonucleotides as therapeutic agents. Pharmacol Ther 1991;52:211-255.
    • (1991) Pharmacol Ther , vol.52 , pp. 211-255
    • Cohen, J.S.1
  • 44
    • 0032700656 scopus 로고    scopus 로고
    • Molecular mechanisms of action of antisense drugs
    • Crooke ST: Molecular mechanisms of action of antisense drugs. Biochim Biophys Acta 1999;1489:31-44.
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 31-44
    • Crooke, S.T.1
  • 45
    • 0033958635 scopus 로고    scopus 로고
    • Antisense therapeutics: Is it as simple as complementary base recognition?
    • Agrawal I, Kandimalla ER: Antisense therapeutics: Is it as simple as complementary base recognition? Mol Med Today 2000;6:72-81.
    • (2000) Mol Med Today , vol.6 , pp. 72-81
    • Agrawal, I.1    Kandimalla, E.R.2
  • 46
    • 0032724911 scopus 로고    scopus 로고
    • Novel mechanisms for antisense-mediated regulation of gene expression
    • Baker BF, Monia BP: Novel mechanisms for antisense-mediated regulation of gene expression. Biochim Biophys Acta 1999;1489:3-18.
    • (1999) Biochim Biophys Acta , vol.1489 , pp. 3-18
    • Baker, B.F.1    Monia, B.P.2


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