2-Aminothiazole-Derived Opioids. Bioisosteric Replacement of Phenols

Journal of Medicinal Chemistry

Volumn 47, Issue 8, 2004, Pages 1886-1888

  Zhang, Ao ^a   Xiong, Wennan ^a   Hilbert, James E ^b   DeVita, Emily K ^b   Bidlack, Jean M ^b   Neumeyer, John L ^a  

^a MCLEAN HOSPITAL   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOTHIAZOLE DERIVATIVE; 4 (1,2,5,6 TETRAHYDRO 1 PROPYL 3 PYRIDYL) 2 THIAZOLAMINE; OPIATE DERIVATIVE; PHENOL DERIVATIVE; PRAMIPEXOLE; TALIPEXOLE;

AMINATION; ANTINOCICEPTION; ARTICLE; BINDING SITE; BIOAVAILABILITY; CYCLIZATION; DERIVATIZATION; DRUG ABUSE; DRUG EXCRETION; DRUG ISOLATION; DRUG RECEPTOR BINDING; HYDROGEN BOND; RECEPTOR AFFINITY;

ANIMALS; BENZOMORPHANS; CHO CELLS; CRICETINAE; MORPHINANS; MORPHINE DERIVATIVES; NARCOTICS; PHENOLS; RADIOLIGAND ASSAY; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 1842450532     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049978n     Document Type: Article

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