The Drosophila centrosome-associated protein CP190 is essential for viability but not for cell division

Journal of Cell Science

Volumn 117, Issue 7, 2004, Pages 1191-1199

  Butcher, R D J ^a,d   Chodagam, S ^b   Basto, R ^b   Wakefield, J G ^b,e   Henderson, D S ^c   Raff, J W ^b   Whitfield, W G F ^d  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c STONY BROOK UNIVERSITY   (United States)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Centrosome; CP190; CP60; Drosophila; Mitosis

Indexed keywords

DROSOPHILA PROTEIN; PROTEIN CP190; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN; CELL DIVISION; CELL VIABILITY; CENTROSOME; CONTROLLED STUDY; DEATH; DEVELOPMENTAL STAGE; GENE MUTATION; HOMOZYGOSITY; INSECT DEVELOPMENT; LARVA; LETHALITY; MICROTUBULE; MITOSIS; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; TISSUE CULTURE CELL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; CELL DIVISION; CELL LINE; CELL SURVIVAL; CENTROSOME; DNA, COMPLEMENTARY; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENES, INSECT; HOMOZYGOTE; MALE; MEIOSIS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOSIS; MUTATION; NUCLEAR PROTEINS;

ANIMALIA; ARACHNIDA; HEXAPODA; INSECTA;

EID: 1842426958     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00979     Document Type: Article

References (28)

1. Adams, R. R., Maiato, H., Earnshaw, W. C. and Carmena, M. (2001). Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation. J. Cell Biol. 153, 865-880.
2. Ashburner, M. (1989). Drosophila, a Laboratory Handbook. New York: Cold Spring Harbor Laboratory Press.
3. Barbosa, V., Yamamoto, R. R., Henderson, D. S. and Glover, D. M. (2000). Mutation of a Drosophila gamma tubulin ring complex subunit encoded by discs degenerate-4 differentially disrupts centrosomal protein localization. Genes Dev. 14, 3126-3139.
4. Bonaccorsi, S., Giansanti, M. G. and Gatti, M. (2000). Spindle assembly in Drosophila neuroblasts and ganglion mother cells. Nat. Cell Biol. 2, 54-56.
5. Chou, T. B. and Perrimon, N. (1996). The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144, 1673-1679.
6. Clemens, J. C., Worby, C. A., Simonson-Leff, N., Muda, M., Maehama, T., Hemmings, B. A. and Dixon, J. E. (2000). Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc. Natl. Acad. Sci. USA 97, 6499-6503.
7. Cooley, L., Kelley, R. and Spradling, A. (1988). Insertional mutagenesis of the Drosophila genome with single P elements. Science 239, 1121-1128.
8. Donaldson, M. M., Tavares, A. A., Ohkura, H., Deak, P. and Glover, D. M. (2001). Metaphase arrest with centromere separation in polo mutants of Drosophila. J. Cell Biol. 153, 663-676.
9. Frasch, M., Glover, D. M. and Saumweber, H. (1986). Nuclear antigens follow different pathways into daughter nuclei during mitosis in early Drosophila embryos. J. Cell Sci. 82, 155-172.
10. Gergely, F., Kidd, D., Jeffers, K., Wakefield, J. G. and Raff, J. W. (2000). D-TACC: A novel centrosomal protein required for normal spindle function in the early Drosophila embryo. EMBO J. 19, 241-252.
11. Giet, R. and Glover, D. M. (2001). Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis. J. Cell Biol. 152, 669-682.
12. Kellogg, D. R. and Alberts, B. M. (1992). Purification of a multiprotein complex containing centrosomal proteins from the Drosophila embryo by chromatography with low-affinity polyclonal antibodies. Mol. Biol. Cell 3, 1-11.
13. Kellogg, D. R., Field, C. M. and Alberts, B. M. (1989). Identification of microtubule-associated proteins in the centrosome, spindle, and kinetochore of the early Drosophila embryo. J. Cell Biol. 109, 2977-2991.
14. Kellogg, D. R., Oegema, K., Raff, J., Schneider, K. and Alberts, B. M. (1995). Cp60 a microtubule associated protein that is localized to the centrosome in a cell cycle specific manner. Mol. Biol. Cell 6, 1673-1684.
15. Laemmli, U. K. (1970). Cleavage of the structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
16. Lee, M. J., Gergely, F., Jeffers, K., Peak-Chew, S. Y. and Raff, J. W. (2001). Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour. Nat. Cell Biol. 3, 643-649.
17. Li, K. J. and Kaufman, T. C. (1996). The homeotic target gene Centrosomin encodes an essential centrosomal component. Cell 85, 585-596.
18. Megraw, T. L., Kan, L. R. and Kaufman, T. C. (2001). Zygotic development without functional mitotic centrosomes. Curr. Biol. 11, 116-120.
19. Megraw, T. L., Li, K., Kao, L. R. and Kaufman, T. C. (1999). The centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila. Development 126, 2829-2839.
20. Oegema, K., Marshall, W. F., Sedat, J. W. and Alberts, B. M. (1997). Two proteins that cycle asynchronously between centrosomes and nuclear structures: Drosophila CP60 and CP190. J. Cell Sci. 110, 1573-1583.
21. Oegema, K., Whitfield, W. G. F. and Alberts, B. (1995). The cell cycle dependent localization of the Cp190 centrosomal protein is determined by the coordinate action of 2 separable domains. J. Cell Biol. 131, 1261-1273.
22. Preston, C. R., Sved, J. A. and Engels, W. R. (1996). Flanking duplications and deletions associated with P-induced male recombination in Drosophila. Genetics 144, 1623-1638.
23. Raff, J. W., Kellogg, D. R. and Alberts, B. M. (1993). Drosophila gamma-tubulin is part of a complex containing two previously identified centrosomal MAPs. J. Cell Biol. 121, 823-835.
24. Roberts, D. (1986). Drosophila, A Practical Approach. Oxford: IRL Press.
25. Wasser, M. and Chia, W. (2000). The EAST protein of Drosophila controls an expandable nuclear endoskeleton. Nat. Cell Biol. 2, 268-275.
26. Whitfield, W. G., Chaplin, M. A., Oegema, K., Parry, H. and Glover, D. M. (1995). The 190 kDa centrosome-associated protein of Drosophila melanogaster contains four zinc finger motifs and binds to specific sites on polytene chromosomes. J. Cell Sci. 108, 3377-3387.
27. Whitfield, W. G., Millar, S. E., Saumweber, H., Frasch, M. and Glover, D. M. (1988). Cloning of a gene encoding an antigen associated with the centrosome in Drosophila. J. Cell Sci. 89, 467-480.
28. Williams, B. C. and Goldberg, M. L. (1994). Determinants of Drosophila zw10 protein localization and function. J. Cell Sci. 107, 785-798.