Crystal structure of murine sCEACAM1a[1, 4]: A coronavirus receptor in the CEA family

EMBO Journal

Volumn 21, Issue 9, 2002, Pages 2076-2086

  Tan, Kemin ^a   Zelus, Bruce D ^a   Meijers, Rob ^a   Liu, Jin Huan ^b   Bergelson, Jeffrey M ^c   Duke, Norma ^d   Zhang, Rongguang ^e   Joachimiak, Andrzej ^e   Holmes, Kathryn V ^f   Wang, Jia Huai ^f  

^a DIVISION OF REPRODUCTIVE BIOLOGY   (United States)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c RESEARCH AND DEVELOPMENT   (Australia)

^d College of Chemistry and Molecular Engineering ^*  (China)

^e UNIVERSITY OF SHEFFIELD   (United Kingdom)

^f DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

Bacterial binding; CEA family; Cell adhesion; Coronavirus receptor; Crystal structure

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CELL ADHESION MOLECULE; UNCLASSIFIED DRUG; VIRUS RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIUM ADHERENCE; BINDING SITE; CRYSTAL STRUCTURE; MOUSE; MURINE HEPATITIS CORONAVIRUS; NEISSERIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; CARCINOEMBRYONIC ANTIGEN; CELL ADHESION MOLECULES; CONSERVED SEQUENCE; CORONAVIRUS; CRYSTALLOGRAPHY, X-RAY; GLYCOPROTEINS; MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, VIRUS; SEQUENCE ALIGNMENT;

BACTERIA (MICROORGANISMS); CORONAVIRUS; MURINAE; MURINE HEPATITIS VIRUS; NEISSERIA;

EID: 18344379124     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.9.2076     Document Type: Article

References (56)

1. A predicted three-dimensional structure for the carcinoembryonic antigen (CEA)
2. Redefined nomenclature for members of the carcinoembryonic antigen family
3. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5
4. Homologue scanning mutagenesis reveals CD66 receptor residues required for neisserial Opa protein binding
5. X-PLOR
6. Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface
7. Crystal structure of two CD46 domains reveals an extended measles virus-binding surface
8. Structural determinants in the sequences of immunoglobulin variable domain
9. A hot spot of binding energy in a hormone-receptor interface
10. The CCP4 suite: Programs for protein crystallography
11. Cloning of the mouse hepatitis virus (MHV) receptor: Expression in human and hamster cell lines confers susceptibility to MHV
12. Several members of the mouse carcinoembryonic antigen-related glycoprotein family are functional receptors for the coronavirus mouse hepatitis virus-A59
13. Mouse hepatitis virus strain A59 and blocking antireceptor monoclonal antibody bind to the N-terminal domain of cellular receptor
14. The molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-Å resolution
15. CEA-related cell adhesion molecule 1: A potent angiogenic factor and a major effector of vascular endothelial growth factor
16. A role for naturally occurring variation of the murine coronavirus spike protein in stabilizing association with the cellular receptor
17. Specific carcinoembryonic antigens of the human digestive system
18. The carcinoembryonic antigen (CEA) family: Structure, suggested functions and expression in normal and malignant tissues
19. Many of the immunoglobulin superfamily domains in cell adhesion molecules and surface receptors belong to a new structural set which is close to that containing variable domains
20. A simplified system for generating recombinant adenoviruses
21. The tyrosine comer: A feature of most Greek key β-barrel proteins
22. Essential role of biliary glycoprotein (CD66a) in morphogenesis of the human mammary epithelial cell line MCF10F
23. The carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cells
24. cis-determinants in the cytoplasmic domain of CEACAM1 responsible for its tumor inhibitory function
25. Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2
26. Improved methods for building protein models in electron density maps and location of errors in these models
27. Molecular dissection of the CD2-CD58 counter-receptor interface identifies CD2 Tyr86 and CD58 Lys34 residues as the functional 'hot spot
28. Structural studies of two rhinovirus serotypes complexed with fragments of their cellular receptor
29. MOLSCRIPT: A program to produce both detailed and schematic plots
30. Structure of an HIV gpl20 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
31. 2.0Å crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region
32. Regulation of human intestinal intraepithelial lymphocyte cytolytic function by biliary glycoprotein (CD66a)
33. Carcinoembryonic antigen cell adhesion molecule 1 functions as an inhibitory activation molecule on mouse T lymphocytes
34. Bgp2, a new member of the carcinoembryonic antigen-related gene family, encodes an alternative receptor for mouse hepatitis viruses
35. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
36. Difference in virus-binding activity of two distinct receptor proteins for mouse hepatitis virus
37. Processing of X-ray diffraction data collected in oscillation mode
38. Identification of a contiguous 6-residue determinant in the MHV receptor that controls the level of virion binding to cells
39. Chinese hamster ovary cell mutants with multiple glycosylation defects for production of glycoproteins with minimal carbohydrate heterogeneity
40. A Shannon entropy analysis of immunoglobulin and T cell receptor
41. Recognition at the cell surface: Recent structural insights
42. Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion
43. Antigenic variation among murine coronaviruses: Evidence for polymorphism on the peplomer glycoprotein E2
44. 7 adhesion to epithelial (E)-cadherin
45. Critical determinants of host receptor targeting by Neisseria meningitidis and Neisseria gonorrhoeae: Identification of Opa adhesiotopes on the N-domain of CD66 molecules
46. Carcinoembryonic antigens are targeted by diverse strains of typable and non-typable Haemophilus influenzae
47. Protein recognition by cell surface receptors: Physiologic receptors versus virus interactions
48. Structural specializations of immunoglobulin superfamily members for adhesion to integrins and viruses
49. Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains
50. Structure of a heterophilic adhesion complex between human CD2 and CD58 (LFA-3) counter-receptors
51. Crystal structure of the human CD4 N-terminal two domain fragment complexed to a class II MHC molecule
52. Homophilic adhesion of human CEACAMI involves N-terminal domain interactions: Structural analysis of the binding site
53. Mutational analysis of the virus and monoclonal antibody binding sites in MHVR, the cellular receptor of the murine coronavirus mouse hepatitis virus strain A59
54. Dimeric association and segmental variability in the structure of human CD4
55. Purified, soluble recombinant mouse hepatitis virus receptor, Bgp1(b) and Bgp2 murine coronavirus receptors differ in mouse hepatitis virus binding and neutralizing activities
56. Pregnancy-specific glycoprotein (PSG) in baboon (Papio hamadryas): Family size, domain structure and prediction of a functional region in primate PSGs