Purified, soluble recombinant mouse hepatitis virus receptor, Bgp1b, and Bgp2 murine coronavirus receptors differ in mouse hepatitis virus binding and neutralizing activities

Journal of Virology

Volumn 72, Issue 9, 1998, Pages 7237-7244

  Zelus, Bruce D ^a   Wessner, David R ^b   Williams, Richard K ^b,d   Pensiero, Michael N ^b,e   Phibbs, Fenna T ^a   Desouza, Mark ^b,f   Dveksler, Gabriela S ^b   Holmes, Kathryn V ^a,b,c  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e NOVARTIS PHARMA AG   (Switzerland)

^f ARMED FORCES RESEARCH INSTITUTE OF MEDICAL SCIENCES   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; RECOMBINANT PROTEIN; VIRUS RECEPTOR;

ARTICLE; BACULOVIRUS; CORONAVIRUS; HEPATITIS VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; VACCINIA VIRUS; VIRUS NEUTRALIZATION; VIRUS RECOMBINANT;

EID: 0031816799     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.9.7237-7244.1998     Document Type: Article

References (71)

1. Asanka, M., and M. M. Lai. 1993. Cell fusion studies identified multiple Cellular factors involved in mouse hepatitis virus entry. Virology 197:732-741
2. Banfield, M. J., D. J. King, A. Mountain, and R. L. Brady. 1997. VL:VH domain rotations in engineered antibodies: crystal structures of the Fab agments from two murine antitumor antibodies and their engineered human constructs. Proteins 29:161-171.
3. Barthold, S.W. 1986. Mouse hepatitis virus: biology and epizootiology, p. 571-601. In P.N. Bhatt, R. O. Jacoby, H. C. Morse III, and A. E. New (ed.), Viral and mycoplasma infections of laboratory rodents. Effects on biomedical research. Academic Press, Orlando, Fla.
4. Barthold, S. W., D. S. Beck, and A. L. Smith. 1986. Mouse hepatitis virus nasoencephalopathy is dependent upon virus strain and host genotype. Arch. Virol. 91:247-256.
5. Bates, P. A., J. Luo, and M. J. Sternberg. 1992. A predicted three-dimensional structure for the carcinoembryonic antigen (CEA). FEBS Lett. 301: 207-214.
6. Boyle, J. F., D. G. Weismiller, and K. V. Holmes. 1987. Genetic resistance to mouse hepatitis virus correlates with absence of virus-binding activity on target tissues. J. Virol. 61:185-189.
7. Brümmendorf, T., and F. G. Rathjen. 1994. Introduction, p. 951-962. In P. Sheterline (ed.), Cell adhesion molecules 1: immunoglobulin superfamily. Academic Press, London, England.
8. Bryn, R. A., I. Sekigawa, S. M. Chamow, J. S. Johnson, T. J. Gregory, D. J. Capon, and J. E. Groopman. 1989. Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4. J. Virol. 63: 4370-4375.
9. Chen, D. S., M. Asanaka, K. Yokomori, F. Wang, S. B. Hwang, H. P. Li, and M. M. Lai. 1995. A pregnancy-specific glycoprotein is expressed in the brain and serves as a receptor for mouse hepatitis virus. Proc. Natl. Acad. Sci. USA 92:12095-12099.
10. Chen, W., V. J. Madden, C. R. Bagnell, Jr., and R. S. Baric. 1997. Hostderived intracellular immunization against mouse hepatitis virus infection. Virology 228:318-332.
11. Collins, A. R., R. L. Knobler, H. Powell, and M. J. Buchmeier. 1982. Monoclonal antibodies to murine hepatitis virus-4 (strain JHM) define the viral glycoprotein responsible for attachment and cell-cell fusion. Virology 119: 358-371.
12. Colston, E., and V. R. Racaniello. 1994. Soluble receptor-resistant poliovirus mutants identify surface and internal capsid residues that control interaction with the cell receptor. EMBO J. 13:5855-5862.
13. Compton, S. R. 1994. Enterotropic strains of mouse coronavirus differ in their use of murine carcinoembryonic antigen-related glycoprotein receptors. Virology 203:197-201.
14. Compton, S. R., S. W. Barthold, and A. L. Smith. 1993. The cellular and molecular pathogenesis of coronaviruses. Lab. Anim. Sci. 43:15-28. (Erratum, 43:203.)
15. Coutelier, J.-P., C. Godfraind, G. S. Dveksler, M. Wysocka, C. B. Cardellichio, H. Nöel, and K. V. Holmes. 1994. B lymphocyte and macrophage expression of carcinoembryonic antigen-related adhesion molecules that serve as receptors for murine coronavirus. Eur. J. Immunol. 24:1383-1390.
16. Delmas, B., and H. Laude. 1990. Assembly of coronavirus spike protein into trimers and its role in epitope expression. J. Virol. 64:5367-5375.
17. Denisova, G., D. Raviv, I. Mondor, Q. J. Sattentau, and J. M. Gershoni. 1997. Conformational transitions in CD4 due to complexation with HIV envelope glycoprotein gp120. J. Immunol, 158:1157-1164.
18. Dindzans, V. J., E. Skamene, and G. A. Levy. 1986. Susceptibility/resistance to mouse hepatitis virus strain 3 and macrophage procoagulant activity are genetically linked and controlled by two non-H2-linked genes. J. Immunol. 137:2355-2360.
19. Dveksler, G. 1998. Unpublished data.
20. Dveksler, G. S., A. A. Basile, C. B. Cardellichio, N. Beauchemin, C. W. Dieffenbach, and K. V. Holmes. 1993. Expression of MHV-A59 receptor glycoproteins in susceptible and resistant strains of mice. Adv. Exp. Med. Biol. 342:267-272.
21. Dveksler, G. S., A. A. Basile, C. B. Cardellichio, and K. V. Holmes. 1995. Mouse hepatitis virus receptor activities of an MHVR/mph chimera and MHVR mutants lacking N-linked glycosylation of the N-terminal domain. J. Virol. 69:543-546.
22. Dveksler, G. S., C. W. Dieffenbach, C. B. Cardellichio, K. McCuaig, M. N. Pensiero, G. S. Jiang, N. Beauchemin, and K. V. Holmes. 1993. Several members of the mouse carcinoembryonic antigen-related glycoprotein family are functional receptors for the coronavirus mouse hepatitis virus-A59. J. Virol. 67:1-8.
23. Dveksler, G. S., S. E. Gagneten, C. A. Scanga, C. B. Cardellichio, and K. V. Holmes. 1996, Expression of the recombinant anchorless N-terminal domain of mouse hepatitis virus (MHV) receptor makes hamster or human cells susceptible to MHV infection. J. Virol. 70:4142-145.
24. Dveksler, G. S., M. N. Pensiero, C. B. Cardellichio, R. K. Williams, G. S. Jiang, K. V. Holmes, and C. W. Dieffenbach. 1991. Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV. J. Virol. 65:6881-6891.
25. Dveksler, G. S., M. N. Pensiero, C. W. Dieffenbach, C. B. Cardellichio, A. A. Basile, P. E. Elia, and K. V. Holmes. 1993. Mouse hepatitis virus strain A59 and blocking antireceptor monoclonal antibody bind to the N-terminal domain of cellular receptor. Proc. Natl. Acad. Sci. USA 90:1716-1720.
26. Edlund, M., I. Blikstad, and B. Obrink. 1996. Calmodulin binds to specific sequences in the cytoplasmic domain of C-CAM and down-regulates C-CAM self-association. J. Biol. Chem. 271:1393-1399.
27. Frana, M. F., J. N. Behnke, L. S. Sturman, and K. V. Holmes. 1985. Proteolytic cleavage of the E2 glycoprotein of murine coronavirus: host-dependent differences in proteolytic cleavage and cell fusion. J. Virol. 56:912-920.
28. Gagneten, S., C. A. Scanga, G. S. Dveksler, N. Beauchemin, D. Percy, and K. V. Holmes. 1996. Attachment glycoproteins and receptor specificity of rat coronaviruscs. Lab. Anim. Sci. 46:159-166.
29. Gallagher, T. M. 1995. Overexpression of the MHV receptor. Effect on progeny virus secretion. Adv. Exp. Med. Biol. 380:331-336.
30. Gallagher, T. M. 1997. A role for naturally occurring variation of the murine coronavirus spike protein in stabilizing association with the cellular receptor. J. Virol. 71:3129-3137.
31. Godfraind, C., S. G. Langreth, C. B. Cardellichio, R. Knobler, J. P. Coutelier, M. Dubois-Dalcq, and K. V. Holmes. 1995. Tissue and cellular distribution of an adhesion molecule in the carcinoembryonic antigen family that serves as a receptor for mouse hepatitis virus. Lab. Invest. 73:615-627.
32. Greve, J. M., C. P. Forte, C. W. Marlor, A. M. Meyer, H. Hoover-Litty, D. Wunderlich, and A. McClelland. 1991. Mechanisms of receptor-mediated rhinovirus neutralization defined by two soluble forms of ICAM-I. J. Virol. 65:6015-6023.
33. Gromeier, M., H. H. Lu, G. Bernhardt, J. J. Harber, J. A. Bibb, and E. Wimmer. 1995. The human poliovirus receptor. Receptor-virus interaction and parameters of disease specificity. Ann. N. Y. Acad. Sci. USA 753:19-36.
34. Hoover-Litty, H., and J. M. Greve. 1993. Formation of rhinovirus-soluble ICAM-1 complexes and conformational changes in the virion. J. Virol. 67: 390-397.
35. James, D. C., M. H. Goldman. M. Hoare, N. Jenkins. R. W. Oliver, B. N. Green, and R. B. Freedman. 1996. Posttranslational processing of recombinant human interferon-gamma in animal expression systems. Protein Sci. 5:331-340.
36. Jarvis, D. L., and E. E. Finn. 1995. Biochemical analysis of the N-glycosylation pathway in baculovirus-infected lepidopteran insect cells. Virology 212:500-511.
37. Kaplan, G., M. S. Freistadt, and V. R. Racaniello. 1990. Neutralization of poliovirus by cell receptors expressed in insect cells. J. Virol. 64:4697-4702.
38. Keck, U., P. Nedéllec, N. Beauchemin, J. A. Thompson, and W. Zimmerman. 1995. The CEA10 gene encodes a secreted member of the murine carcinoembryonic antigen family and is expressed in the placenta, gastrointestinal tract and bone marrow. Eur. J. Biochem. 229:455-464.
39. Knobler, R., L. A. Tunison, and M. B. Oldstone. 1984. Host genetic control of mouse hepatitis virus type 4 (JHM strain) replication. I. Restriction of virus amplification and spread in macrophages from resistant mice. J. Gen. Virol. 65:1543-1548.
40. Lange, G., S. J. Lewis, G. N. Murshudov, G. G. Dodson, P. C. Moody, J. P. Turkenburg, A. N. Barclay, and R. L. Brady. 1994. Crystal structure of an extracellular fragment of the rat CD4 receptor containing domains 3 and 4. Structure 2:469-481.
41. Lin, S., W. Luo, K. Earley, P. Cheung, and D. C. Hixson. 1995. Structure and function of C-CAM1: effects of the cytoplasmic domain on cell aggregation. Biochem. J. 311:239-245.
42. McCuaig, K., M. Rosenberg, P. Nédellec, C. Turbide, and N. Beauchemin. 1993. Expression of the Bgp gene and characterization of mouse colon biliary glycoprotein isoforms. Gene 127:173-183.
43. Moore, J. P., J. A. McKeating, W. A. Norton, and Q. J. Sattentau. 1991. Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virions: gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralization by soluble CD4. J. Virol. 65:1133-1140.
44. Nédellec, P., G. S. Dveksler, E. Daniels, C. Turbide, B. Chow, A. A. Basile, K. V. Holmes, and N. Beauchemin. 1994. Bgp2, a new member of the carcinoembryonic antigen-related gene family, encodes an alternative receptor for mouse hepatitis viruses. J. Virol. 68:4525-537.
45. Norkin, L. C. 1995. Virus receptors: implications for pathogenesis and the design of antiviral agents. Clin. Microbiol. Rev. 8:293-315.
46. Ohlin, A., H. Hoover-Litty, G. Sanderson, A. Paessens, S. L. Johnson, S. T. Holgate, E. Huguenel, and J. M. Greve. 1997. Spectrum of activity of soluble intercellular adhesion molecule-1 against rhinovirus reference strains and field isolates. Antimicrob. Agents Chemother. 38:1413-1415.
47. Ohtsuka, N., and F. Taguchi. 1997. Mouse susceptibility to mouse hepatitis virus infection is linked to viral receptor genotype. J. Virol. 71:8860-8863.
48. Ohtsuka, N., Y. K. Yamada, and F. Taguchi. 1996. Difference in virus-bindina activity of two distinct receptor proteins for mouse hepatitis virus. J. Gen. Virol. 77:1683-1692.
49. Pensiero, M. N., G. S. Dveksler, C. B. Cardellichio, G. Jiang, P. E. Elia, C. W. Dieffenbach, and K. V. Holmes. 1992. Binding of the coronavirus mouse hepatitis virus A59 to its receptor expressed from a recombinant vaccinia virus depends on posttranslational processing of the receptor glycoprotein. J. Virol. 66:4028-39.
50. Racaniello, V. R. 1991. Virus-receptor interaction in poliovirus entry and pathogenesis. Harvey Lect. 87:1-16.
51. Rao, P. V., and T. M. Gallagher. 1997. Identification of a contiguous 6-residue determinant in the MHV receptor that controls the level of virion binding to cells. Virology 229:336-348.
52. Rowe, C. L., S. C. Baker, M. J. Nathan, and J. O. Fleming. 1997. Evolution of mouse hepatitis virus: detection and characterization of spike deletion variants during persistent infection. J. Virol. 71:2959-2969.
53. Rudert, F., A. M. Saunders, S. Rebstock, J. A. Thompson, and W. Zimmerman. 1992. Characterization of murine carcinoembryonic antigen gene family members. Mamm. Genome 3:262-273.
54. Saeki, K., N. Ohtsuka, and F. Taguchi. 1997. Identification of spike protein residues of murine coronavirus responsible for receptor-binding activity by use of soluble receptor-resistant mutants. J. Virol. 71:9024-9031.
55. Signoret, N., P. Poignard, D. Blanc, and Q. J. Sattentau. 1993. Human and simian immunodeficiency viruses: virus-receptor interactions. Trends Microbiol. 1:328-333.
56. Smith, A. L., C. B. Cardellichio, D. F. Winograd, M. S. de Souza, S. W. Barthold, and K. V. Holmes. 1991. Monoclonal antibody to the receptor for murine coronavirus MHV-A59 inhibits viral replication in vivo. J. Infect. Dis. 163:879-882.
57. Smith, M. S., R. E. Click, and P. Plagemann. 1984. Control of mouse hepatitis virus replication in macrophages by a recessive gene on chromosome 7. J. Immunol. 133:428-432.
58. Sridhar, P., A. K. Panda, R. Pal, G. P. Talwar, and S. E. Hasnain. 1993 Temporal nature of the promoter and not relative strength determines the expression of an extensively processed protein in a baculovirus system. FEBS Lett. 315:282-286.
59. Sturman, L. S., K. V. Holmes, and J. Behnke. 1980. Isolation of coronavirus envelope glycoproteins and interaction with the viral nucleocapsid. J. Virol. 33:449-462.
60. Sturman, L. S., C. S. Ricard, and K. V. Holmes. 1990. Conformational change of the coronavirus peplomer glycoprotein at pH 8.0 and 37°C correlates with virus aggregation and -irus-induced cell fusion. J. Virol. 64:3042-3050.
61. Turbide, C., M. Rojas, C. P. Stanners, and N. Beauchemin. 1991. A mouse carcinoembryonic antigen gene family member is a calcium-dependent cell adhesion molecule. J. Biol. Chem. 266:309-315.
62. Wege, H., S. Siddell, and V. ter Meulan. 1982. The biology and pathogenesis of coronaviruses. Curr. Top. Microbiol. Immunol. 99:165-200.
63. Weiser, W., I. Vellisto, and F. B. Bang. 1976. Congenic strains of mice susceptible and resistant to mouse hepatitis virus. Proc. Soc. Exp. Biol. Med. 152:499-502.
64. Wessner, D. R., P. C. Shick, J.-H. Lu, C. B. Cardellichio, S. E. Gagneten, N. Beauchemin, K. V. Holmes, and G. S. Dveksler. 1998. Mutational analysis of the virus and monoclonal antibody binding sites in MHVR, the cellular receptor of the murine coronavirus mouse hepatitis virus strain MHV-A59. J. Virol. 72:1941-1948.
65. Williams, R. K., G. S. Jiang, and K. V. Holmes 1991. Receptor for mouse hepatitis virus is a member of the carcinoembryonic antigen family of glycoproteins. Proc. Natl. Acad. Sci. USA 88:5533-5536.
66. Williams, R. K., G. S. Jiang, S. W. Snyder, M. F. Frana, and K. V. Holmes. 1990. Purification of the 110-kilodalton glycoprotein receptor for mouse hepatitis virus (MHV)-A59 from mouse liver and identification of a non-functional, homologous protein in MHV-resistant SJL/J mice. J. Virol. 64: 3817-3823.
67. Williams, R. K., S. W. Snyder, and K. V. Holmes. 1990. MHV-resistant SJL/J mice express a non-functional homolog to the MHV receptor glycoprotein. Adv. Exp. Med. Biol. 276:45-50.
68. Yafal, A. G., G. Kaplan, V. R. Racaniello, and J. M. Hogle. 1993. Characterization of poliovirus conformational alteration mediated by soluble cell receptors. Virology 197:501-505.
69. Yokomori, K., M. Asanaka, S. A. Stohlman, and M. M. Lai. 1993. A spike protein-dependent cellular factor other than the viral receptor is required for mouse hepatitis virus entry. Virology 196:45-56.
70. Yokomori, K., and M. M. Lai. 1992. Mouse hepatitis virus utilizes two carcinoembryonic antigens as alternative receptors. J. Virol. 66:6194-6199.
71. Yokomori, K., and M. M. Lai. 1992. The receptor for mouse hepatitis virus in the resistant mouse strain SJL is functional: implications for the requirement of a second factor for viral infection. J. Virol. 66:6931-6938.