Molecular basis for leukocyte integrin α(E)β7 adhesion to epithelial (E)-cadherin

Journal of Experimental Medicine

Volumn 191, Issue 9, 2000, Pages 1555-1567

  Taraszka, Karen S ^a   Higgins, Jonathan M G ^a   Tan, Kemin ^a   Mandelbrot, Didier A ^a,b   Wang, Jia Huai ^a   Brenner, Michael B ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Cadherins; Cell adhesion; Integrins; Protein binding; T lymphocytes

Indexed keywords

CADHERIN; CELL ADHESION MOLECULE; FIBRONECTIN; IMMUNOGLOBULIN G; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 2; INTERCELLULAR ADHESION MOLECULE 3; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; SOLVENT; UVOMORULIN; VASCULAR CELL ADHESION MOLECULE 1;

ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CELL ADHESION; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN LOCALIZATION; T LYMPHOCYTE; TISSUE SPECIFICITY; VASCULAR ENDOTHELIUM;

AMINO ACID SEQUENCE; BINDING SITES; BREAST; CADHERINS; CELL ADHESION; CELL ADHESION MOLECULES; EPITHELIAL CELLS; FEMALE; FIBRONECTINS; HUMANS; IMMUNOGLOBULINS; INTEGRINS; LEUKOCYTES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; SEQUENCE ANALYSIS, PROTEIN; T-LYMPHOCYTES;

EID: 0034194166     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.9.1555     Document Type: Article

References (51)

1. 7 mediates adhesion of T lymphocytes to epithelial cells. J. Immunol. 150:3459-3470.
2. 7 with E-cadherin. J. Cell Biol. 140:197-210.
3. E (CD103)-deficient mice. J. Immunol. 162:6641-6649.
4. E subunit. Unusual structure and restricted RNA distribution. J. Biol. Chem. 269: 6016-6025.
5. 2) integrin. Proc. Natl. Acad. Sci. USA. 92:10277-10281.
6. Lee, J.O., P. Rieu, M.A. Arnaout, and R. Liddington. 1995. Crystal structure of the A domain from the α subunit of integrin CR3 (CD11b/CD18). Cell. 80:631-638.
7. Qu, A., and D.J. Leahy. 1996. The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin. Structure. 4:931-942.
8. 1. J. Biol. Chem. 272:28512-28517.
9. Baldwin, E.T., R.W. Sarver, G.L. Bryant, K.A. Curry, M.B. Fairbanks, B.C. Finzel, R.L. Garlick, R.L. Heinrikson, N.C. Horton, L.L. Kelley, et al. 1998. Cation binding to the integrin CD11b I domain and activation model assessment. Structure. 6:923-935.
10. Tan, K., J.M. Casasnovas, J.H. Liu, M.J. Briskin, T.A. Springer, and J.H. Wang. 1998. The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition. Structure. 6:793-801.
11. Viney, J.L., S. Jones, H.H. Chiu, B. Lagrimac, M.E. Renz, L.G. Presta, D. Jackson, K.J. Hillan, S. Lew, and S. Fong. 1996. Mucosal addressin cell adhesion molecule-1: a structural and functional analysis demarcates the integrin binding motif. J. Immunol. 157:2488-2497.
12. Jones, E.Y., K. Harlos, M.J. Bottomley, R.C. Robinson, P.C. Driscoll, R.M. Edward, J.M. Clements, T.J. Dudgeon, and D.I. Stuart. 1995. Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule 1 at 1.8 Å resolution. Nature. 373:539-544.
13. Vonderheide, R.H., T.F. Tedder, T.A. Springer, and D.E. Staunton. 1994. Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4. J. Cell Biol. 125:215-222.
14. Casasnovas, J.M., T.A. Springer, J.H. Liu, S.C. Harrison, and J.H. Wang. 1997. Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface. Nature. 387:312-315.
15. Staunton, D.E., M.L. Dustin, H.P. Erickson, and T.A. Springer. 1990. The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus. Cell. 61:243-254.
16. Nose, A., K. Tsugi, and M. Takeichi. 1990. Localization of the specificity determining sites in cadherin cell adhesion molecules. Cell, 61:147-155.
17. Overduin, M., T.S. Harvey, S. Bagby, K.I. Tong, P. Yau, M. Takeichi, and M. Ikura. 1995. Solution structure of the epithelial cadherin domain responsible for selective cell adhesion. Science. 267:386-389.
18. Shapiro, L., A.M. Fannon, P.D. Kwong, A. Thompson, M.S. Lehmann, G. Gruebel, J.F. Legrand, J. Als-Nielsen, D.R. Colman, and W. Hendrickson. 1995. Structural basis of cell-cell adhesion by cadherins. Nature. 374:327-337.
19. Nagar, B., M. Overduin, M. Ikura, and J.M. Rini. 1996. Structural basis of calcium-induced E-cadherin rigidification and dimenzation. Nature. 380:360-364.
20. Tamura, K., W.S. Shan, W.A. Hendrickson, D.R. Colman, and L. Shapiro. 1998. Structure-function analysis of cell adhesion by neural (N-) cadherin. Neuron. 20:1152-1163.
21. 2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation. EMBO (Eur. Mol. Biol. Organ.) J. 18:1738-1747.
22. 7 integrin. Eur. J. Immunol. 24:2832-2841.
23. 7 integrin. Nature. 372:190-193.
24. 2+-dependent cell-cell adhesion molecule homologous to mouse placental cadherin: its low expression in human placental tissues. J. Cell Biol. 109:1787-1794.
25. Russell, G.J., C.M. Parker, A. Sood, E. Mizogushi, E.C. Ebert, A.K. Bhan, and M.B. Brenner. 1996. P126 (CDw101), a costimulatory molecule preferentially expressed on mucosal T lymphocytes. J. Immunol. 157:3366-3374.
26. Abitorabi, M.A., R.K. Pachynski, R.E. Ferrando, M. Tidswell, and D.J. Erle. 1997. Presentation of integrins on leukocyte microvilli: a role for the extracellular domain in determining membrane localization. J. Cell Biol. 139:563-371.
27. Ho, S.N., H.D. Hunt, R.M. Horton, J.K. Pullen, and L.R. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene. 77:51-59.
28. 7. Common themes among integrin-Ig family interactions. J. Immunol. 156:719-726.
29. Watabe, J., A. Nagafuchi, S. Tsukita, and M. Takeichi. 1994. Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line. J. Cell Biol. 127:247-256.
30. Tomschy, A., C. Fasuer, and R.E.J. Landwehr. 1996. Homophilic adhesion of E-cadherin occurs by a co-operative two-step interaction of N-terminal domains. EMBO (Eur. Mol. Biol. Organ.) J. 15:3507-3514.
31. Brieher, W.M., A.S. Yap, and B.M. Gumbiner. 1996. Lateral dimenzation is required for the homophilic binding activity of C-cadherin. J. Cell Biol. 135:487-496.
32. 7 in the N-terminal domain of E-cadherin. J. Biol. Chem. 271:30909-30915.
33. 1). J. Cell Biol. 124:6111-608.
34. 4 integrin binding interfaces on VCAM-1 and MAdCAM-1. Integrin binding footprints identity accessory binding sites that play a role in integrin specificity. J. Biol. Chem. 272: 19429-19440.
35. 1. J. Cell Biol. 125:1395-1406.
36. Fisher, K.L., J. Lu, K.J. Kim, L.G. Presta, and S.C. Bodary. 1997. Identification of the binding site in intercellular adhesion molecule 1 for its receptor, leukocyte function-associated antigen 1. Mol. Biol. Cell. 8:501-515.
37. Wang, J., and T.A. Springer. 1998. Structural specializations of immunoglobulin superfamily members for adhesion to integrins and viruses. Immunol. Rev. 163:197-215.
38. Leahy, D.J., I. Aukhil, and H.P. Erickson. 1996. 2.0 Å crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region. Cell. 84:155-164.
39. 4 integrin interaction. Proc. Natl. Acad. Sci. USA. 92:5714-5718.
40. Osborn, L., C. Vassallo, and C.D. Benjamin. 1992. Activated endothelium binds lymphocytes through a novel binding site in the alternately spliced domain of vascular cell adhesion molecule-1. J. Exp. Med. 176:99-107.
41. 7 under different activity states. J. Immunol. 155:5257-5267.
42. Bella, J., P.R. Kolatkar, C.W. Marlor, J.M. Greve, and M.G. Rossman. 1998. The structure of the two amino-terminal domains of human ICAM-1 suggest how it functions as a rhinovirus receptor and as an LFA-1 integrin ligand. Proc. Natl. Acad. Sci. USA. 95:4140-4145.
43. Casasnovas, J.M., T. Stehle, J.H. Lie, J.H. Wang, and T.A. Springer. 1998. A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1. Proc. Natl. Acad. Sci. USA. 95:4134-4139.
44. Bell, E.D., A.P. May, and D.L. Simmons. 1998. The leukocyte function-associated antigen-1 (LFA-1)-binding site on ICAM-3 comprises residues on both faces of the first immunoglobulin domain. J. Immunol. 161:1363-1370.
45. Klickstein, L.B., M.R. York, A.R. de Fougerolles, and T.A. Springer. 1996. Localization of the binding site of intercellular adhesion molecule-3 (ICAM-3) for lymphocyte function-associated antigen-1 (LFA-1). J. Biol. Chem. 271:23920-23927.
46. Holness, C.L., P.A. Bates, A.J. Little, C.D. Buckley, A. McDowall, D. Bossy, N. Hogg, and D.L. Simmons. 1995. Analysis of the binding site on intercellular adhesion molecule 3 for the leukocyte integrin lymphocyte function-associated antigen 1. J. Biol. Chem. 270:877-884.
47. Hynes, R.O. 1992. Integrins: versatility, modulation, and signaling in cell adhesion. Cell. 69:11-25.
48. Blaschuk, O., R. Sullivan, S. David, and Y. Pouliot. 1990. Identification of a cadherin cell adhesion recognition sequence. Dev. Biol. 139:227-229.
49. Smith, T.J., L.A. Ducharme, S.K. Shaw, C.M. Parker, M.B. Brenner, P.J. Kilshaw, and J.H. Weis. 1994. Murine M290 integrin expression modulated by mast cell activation. Immunity. 1:393-403.
50. 7 by a major subpopulation of dendritic cells in mice. Eur. J. Immunol. 23:3365-3368.
51. Kabsch, W., and C. Sandler. 1983. Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers. 22:2577-2637.