Validation of human physiologically based pharmacokinetic model for vinyl acetate against human nasal dosimetry data

Toxicological Sciences

Volumn 85, Issue 1, 2005, Pages 460-467

  Hinderliter, Paul M ^a   Thrall, K D ^b   Corley, R A ^b   Bloemen, L J ^c   Bogdanffy, M S ^a  

^a DUPONT COMPANY   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^c DOW BENELUX B V   (Netherlands)

Author keywords

Human; Nasal dosimetry; PBPK modeling; Vinyl acetate

Indexed keywords

VINYL ACETATE;

ADULT; ARTICLE; ATMOSPHERE; BREATH ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOSIMETRY; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; ION TRAP MASS SPECTROMETRY; NASOPHARYNX; NORMAL HUMAN; OCCUPATIONAL EXPOSURE; PROSPECTIVE STUDY; RHINOMETRY; RISK ASSESSMENT; SENSITIVITY ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TOXICOKINETICS; VALIDATION PROCESS;

ADOLESCENT; ADULT; FEMALE; HUMANS; INHALATION EXPOSURE; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; NASAL CAVITY; OLFACTORY MUCOSA; RISK ASSESSMENT; SPECIES SPECIFICITY; VINYL COMPOUNDS;

RODENTIA;

EID: 18144425184     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfi091     Document Type: Article

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