Cisplatin-induced apoptosis is enhanced by hypoxia and by inhibition of mitochondria in renal collecting duct cells

Toxicological Sciences

Volumn 85, Issue 1, 2005, Pages 735-742

  Schwerdt, Gerald ^a   Freudinger, Ruth ^a   Schuster, Claudia ^a   Weber, Florian ^a   Thews, Oliver ^a   Gekle, Michael ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Apoptosis; Cisplatin; Collecting duct; Hypoxia; Mitochondria

Indexed keywords

CASPASE 3; CISPLATIN; CITRININ; DNA; LACTATE DEHYDROGENASE; LACTIC ACID; OLIGOMYCIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; ROTENONE;

ACIDIFICATION; ALKALINIZATION; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL HYPOXIA; CELL PH; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; KIDNEY COLLECTING TUBULE; MITOCHONDRIAL RESPIRATION; NEPHROTOXICITY; NONHUMAN; RESPIRATORY CHAIN;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASES; CELL HYPOXIA; CELL LINE; CELL SURVIVAL; CISPLATIN; DOGS; HYDROGEN-ION CONCENTRATION; KIDNEY TUBULES, COLLECTING; MITOCHONDRIA;

EID: 18144424812     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfi117     Document Type: Article

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