Methoxypoly(ethylene glycol)-conjugated carboxypeptidase A for solid tumor targeting: Part I: Synthesis and characterization

Journal of Controlled Release

Volumn 104, Issue 1, 2005, Pages 129-139

  Ton, Giangthy N ^a   Fine, Jason P ^b   Kwon, Glen S ^c  

^a University of Wisconsin Health   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Catalytic efficiency (k cat Km); Half life (t1 2); PEGylation; Turnover number (kcat)

Indexed keywords

ANTIBODIES; BIOSYNTHESIS; CATALYSIS; CHEMOTHERAPY; DRUG PRODUCTS; FRACTIONATION; MOLECULAR WEIGHT; ONCOLOGY; POLYETHYLENE GLYCOLS; SIZE EXCLUSION CHROMATOGRAPHY; TOXICITY; TUMORS;

ANTICANCER AGENTS; CYTOTOXIC AGENTS; CYTOTOXICITY; ENZYME DELIVERY;

ENZYMES;

CARBOXYPEPTIDASE A; ETHYLENE GLYCOL;

ARTICLE; BINDING AFFINITY; DRUG CONJUGATION; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVITY; ENZYME STABILITY; GEL PERMEATION CHROMATOGRAPHY; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN BINDING; TUMOR;

EID: 18144389796     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.01.016     Document Type: Article

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