Mucosal delivery of microparticle encapsulated ESAT-6 induces robust cell-mediated responses in the lung milieu

Journal of Controlled Release

Volumn 104, Issue 1, 2005, Pages 67-77

  Carpenter, Zoë K ^a   Williamson, E Diane ^a   Eyles, Jim E ^a  

^a DEFENCE SCIENCE AND TECHNOLOGY LABORATORY   (United Kingdom)

Author keywords

ESAT 6; Intranasal; M. tuberculosis; Microspheres; Vaccine

Indexed keywords

BACTERIA; CELLS; DISEASES; FLUORESCENCE; IMMUNOLOGY;

FLUORESCENCE ACTIVATED CELL SORTING (FACS); MICROPARTICLES; MUCOSAL DELIVERY; TUBERCULOSIS INFECTION;

ANTIGENS;

ALUMINUM HYDROXIDE; CD4 ANTIGEN; CD8 ANTIGEN; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; HERMES ANTIGEN; INTERLEUKIN 4; MICROSPHERE; MYCOBACTERIUM VACCINE; POLYLACTIDE; T LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ASSAY; CELL COMPARTMENTALIZATION; CELL COUNT; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG DELIVERY SYSTEM; DRUG MECHANISM; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; IMMUNE SYSTEM; IMMUNIZATION; LUNG; MEDIASTINUM LYMPH NODE; MICROENCAPSULATION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; T LYMPHOCYTE SUBPOPULATION;

EID: 18144368071     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.01.014     Document Type: Article

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