DNA vaccines against tuberculosis

Immunology and Cell Biology

Volumn 75, Issue 6, 1997, Pages 591-594

  Lowrie, Douglas B ^a   Silva, Celio L ^b   Tascon, Ricardo E ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antigen presentation; Cytotoxic immunity; Passive transfer of immunity; Recombinant cell mediated immunity; T lymphocytes; Tuberculosis vaccines

Indexed keywords

BCG VACCINE; CD8 ANTIGEN; DNA VACCINE; GAMMA INTERFERON; HEAT SHOCK PROTEIN; HERMES ANTIGEN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CELLULAR IMMUNITY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; IMMUNOLOGICAL MEMORY; INTERFERON PRODUCTION; INTRAMUSCULAR DRUG ADMINISTRATION; LYMPHOCYTE CLONE; MOUSE; NONHUMAN; PASSIVE IMMUNIZATION; SPLEEN CELL; TUBERCULOSIS; VACCINATION;

ANIMALIA; MYCOBACTERIUM BOVIS BCG;

EID: 0031409105     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1038/icb.1997.93     Document Type: Conference Paper

References (8)

1. Silva CL, Lowrie DB. A single mycobacterial protein (hsp65) expressed by a transgenic antigen-presenting cell vaccinates mice against tuberculosis. Immunology 1994; 82: 244-8.
2. Silva CL, Silva MF, Pietro RCLR, Lowrie DB. Protection against tuberculosis by passive transfer with T-cell clones recognizing mycobacterial heat-shock protein 65. Immunology 1994; 83: 341-6.
3. Silva CL, Silva MF, Pietro RCLR, Lowrie DB. Characterization of T cells that confer a high degree of protective immunity against tuberculosis in mice after vaccination with tumor cells expressing mycobacterial hsp65. Infect. Immun. 1996; 64: 2400-7.
4. Ulmer JB, Donnelly JJ, Parker SE et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993; 259: 1745-9.
5. Tascon RE, Colston MJ, Ragno S, Stavropoulos E, Gregory D, Lowrie DB. Vaccination against tuberculosis by DNA injection. Nat. Med. 1996; 2: 888-92.
6. Tascon R, Stavropoulos E, Colston MJ, Lowrie DB. Polynucleotide vaccination induces a significant protective immune response against mycobacteria. In: Brown F, Norrby E, Burton D, Mekalanos J (eds). Vaccines 96: Molecular Approaches to the Control of Infectious Diseases. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 1996; 45-9.
7. Lowrie DB, Silva CL, Colston MJ, Ragno S, Tascon R. Protection against tuberculosis by a plasmid DNA vaccine. Vaccine 1997; 15: 834-8.
8. Lowrie DB, Colston MJ, Tascon RE, Silva CL. DNA encoding individual mycobacterial antigens protects mice against tuberculosis. In: Brown F, Burton D, Doherty P, Mekalanos J, Norrby E (eds). Vaccines 97: Molecular Approaches to the Control of Infectious Diseases. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 1997; 163-6.