Effect of testosterone and steroids homologues on indolamines and lipid peroxidation in rat brain

Journal of Steroid Biochemistry and Molecular Biology

Volumn 94, Issue 4, 2005, Pages 369-373

  Guzmán, David Calderón ^a   Mejía, Gerardo Barragán ^a   Vázquez, Ivonne Espitia ^a   García, Ernestina Hernández ^a   Del Angel, Daniel Santamaría ^a   Olguín, Hugo Juárez ^a,b  

^a INSTITUTO NACIONAL DE PEDIATRÍA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Brain; Lipid peroxidation; Serotonin; Steroids; Testosterone

Indexed keywords

3BETA ACETOXY 16ALPHA,17ALPHA EPOXY 4 PREGNEN 20 ONE; 3BETA ACETOXY 5,16 PREGNADIEN 20 ONE; 4 PREGNEN 17 HYDROXY 3 ONE; 5 HYDROXYTRYPTOPHAN; CARBON; FREE RADICAL; INDOLEAMINE; ORTHO CRESOL; SEROTONIN; STEROID; STEROID 5ALPHA REDUCTASE; TESTOSTERONE DERIVATIVE; THIOBARBITURIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN; CONTROLLED STUDY; ENZYME ACTIVITY; HORMONE ACTION; LIPID PEROXIDATION; MALE; MOLECULAR INTERACTION; NONHUMAN; ORGAN WEIGHT; PROSTATE; RAT;

ANIMALIA; RATTUS NORVEGICUS;

EID: 18044392405     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2004.11.006     Document Type: Article

References (34)

1. J.A. Tresguerres, Biosíntesis de las hormonas sexuales en el ovario, in: Fisiología y Patología, Díaz de Santos, Madrid, 1995, pp. 49-58.
2. C. Kubli Acción neuromoduladora de las hormonas esteroides T.A. Zarate Fundamentos de Neuroendocrinología 1993 Fondo de Cultura Económica Mexico D.F. pp. 92-102
3. O. Robel, and E.E. Baulieu Neurosteroids: biosynthesis and function Trends Endocrinol. Metab. 5 1994 1 8
4. J. Hirosumi, O. Nakayama, and T. Fagan FK143 a novel nonsteroidal inhibitor of steroid 5α-reductase: in vitro effects on human and animal prostatic enzymes J. Steroid Biochem. Mol. Biol. 52 1995 357 363
5. E. Baulieu, M. Schumacher, and H. Koening Progesterone as a neurosteroid: actions within the nervous system Cell Mol. Neurobiol. 16 1996 143 154
6. Y. Jung-Testas, M. Schumacher, P. Robel, and E.E. Baulieu The neurosteroid progesterone increases the expression of mielin proteins (MBP and CNPase) in rat oligodendrocytes in primary culture Cell Mol. Neurobiol. 16 1996 439 443
7. R. Rupprecht The neuropsychopharmacological potential of neuroactive steroids J. Psychiat. Res. 31 1997 297 314
8. M.B. Ruíz-Larrea, C. Martin, R. Martínez, R. Navarro, M. Lacort, and N.J. Miller Antioxidant activities of estrogens against aqueous and lipophilic radicals: differences between phenol and catechol estrogens Chem. Phys. Lipids 105 2000 179 188
9. E. Ahlbom, L. Grandison, E. Bonfoco, B. Zhivotovsky, and S. Ceccatelli Androgen treatment of neonatal rats decreases susceptibility of cerebellar granule neurons to oxidative stress in vitro Eur. J. Neurosci. 11 1999 1285 1291
10. J. Lehotssky, P. Kaplan, P. Racay, M. Matejovicova, A. Drgova, and V. Mezesova Membrane ion transport systems during oxidative stress in rodent brain: protective effect of stobadine and other antioxidants Life Sci. 65 1999 1951 1958
11. G. Baydas, R.J. Reiter, V.S. Nedzvetskii, A. Yasar, M. Tscu, and F. Ozveren Melatonin protects the central nervous system of rats against toluene-containing thinner intoxication by reducing reactive gliosis Toxicol. Lett. 137 2003 169 174
12. G.D. Calderón, I.J. Hernández, and S.L. Castilla El ozono como molécula reactiva Concepto actual. Perinatol. Reprod. Hum. 14 2000 115 123
13. J. Baelum, L. Molhave, S.H. Hansen, and M. Vaeth Metabolic interaction between toluene, trichloroethylene and n-hexane in humans Scand. J. Work Environ. Health. 24 1998 30 37
14. W.C. Dennis Glutamate neurotoxicity and diseases of the nervous system Neuron 1 1998 623 634
15. A.V. Juorio, and P.H. Yu Effects of benzene and other organic solvents on the decarboxylation of some brain aromatic l-aminoacids Biochem. Pharmacol. 3 1985 1381 1387
16. +-ATPase related lipid peroxidation in ischemic and reperfused rabbit kidney Gen. Pharmacol. 25 1994 341 344
17. M. Chen, and A.D. Kligerman Evaluation of the genotoxicity of cresols using sister-chromatid exchange (SCE) Mut. Res. 137 1984 51 55
18. M.J. Ellenhorn, S. Schonwald, G. Ordog, and J. Wasserberger Ellenhorńs Medical Toxicology: Diagnosis and Treatment of Human Poisoning 2nd ed. 1997 Williams and Wilkins Baltimore, MD pp. 1211
19. M. Korpela, and H. Tahti The effect of in vitro and in vivo toluene exposure on rat erythrocyte and synaptosome membrane integral enzymes Pharmacol. Toxicol. 63 1988 30 32
20. +-Adenosine triphosphatase and phospholipid methylation J. Pharmacol. Exp. Ther. 253 1990 1189 1197
21. G.D. Calderón, R.N. Labra, and I.J. Hernández Evaluación farmacológica de dos nuevos fármacos esteroidales sintéticos, con posible actividad antiandrogénica (estudio in vivo) Rev. Mex. Cienc. Farm. 28 1997 13 16
22. M.C. Gutteridge, and B. Halliwell The Measurement and Mechanism of Lipid Peroxidation in Biological Systems 1999 Elsevier Science
23. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the folin phenol reagent J. Biol. Chem. 193 1951 265 275
24. G.D. Calderón, I.J. Hernández, V.I. Espítia, M.G. Barragán, G.E. Hernández, A.D. Santamaría, H. Juárez, and Pyridoxine Regardless of serotonin levels increases production of 5-hydroxytryptophan in rat brain Arch. Med. Res. 35 2004 271 274
25. E.T. Bratoeff, R. Flores, E.L. Ramírez, C.O. Flores, G.D. Calderón, and E.G. Hernández Síntesis de nuevos inhibidores de 5α-reductasa Rev. Mex. Cienc. Farm. 28 1997 13 19
26. a Ed., México, D.F., 1999, pp. 200.
27. N.N. Tam, S. Ghatak, and S.M. Ho Sex hormone-induced alterations in the activities of antioxidant enzymes and lipid peroxidation status in the prostate of noble rats Prostate 55 2003 1 8
28. K. Huh, U.S. Shin, J.W. Choi, and S.I. Lee Effect of sex hormones on lipid peroxidation in rat liver Arch. Pharm. Res. 17 1994 109 114
29. E. Ahlbom, G.S. Prins, and S. Ceccatelli Testosterone protects cerebellar granule cells from oxidative stress-induced cell death through a receptor mediated mechanism Brain Res. 892 2001 255 262
30. A.D. Mooradian Antioxidant properties of steroids J. Steroids Biochem. Mol. Biol. 45 1993 509 511
31. W. Klinger, A. Lupp, and E. Karge Estradiol, testosterone, dehydroepiandrosterone and androstenedione: novel derivatives and enantiomers. Interactions with rat liver microsomal cytochrome P450 and antioxidant/radical scavenger activities in vitro Toxicol. Lett. 128 2002 129 144
32. H. Vedder, N. Anthes, G. Stumm, C. Wurz, C. Behl, and J.C. Krieg Estrogen hormones reduce lipid peroxidation in cells and tissues of the central nervous system J. Neurochem. 72 1999 2531 2538
33. J. Liu, and A. Mori Monoamine metabolism provides an antioxidant defense in the brain against oxidant- and free radical-induced damage Arch. Biochem. Biophys. 302 1993 118 127
34. J.B. Hutchison, and M. Schumacher Development of testosterone- metabolizing pathways in the avian brain: enzyme localization and characteristics Dev. Brain Res. 25 1986 33 42